OJNeph  Vol.3 No.3 , September 2013
Surgical Complications and Evolution of Grafts in Children with Renal Transplantation at Cayetano Heredia National Hospital
Abstract: Objective: This study aims to determine surgical complications and graft outcome in children undergoing renal transplantation at Cayetano Heredia National Hospital (CHNH). Materials and Methods: A case study series focused on the incidence of surgical complications and graft outcome in pediatric patients with end stage renal disease (ESRD) who underwent renal transplant (RT) between December 2007 and March 2011. Results: The study described 29 pediatric transplant patients whose average age was 13.69 ± 3.38 (6.2-17.9) years. The etiology of end stage renal disease (ESRD) was renal hypoplasia in 12 patients (41.38%), primary glomerulopathy in 10 patients (34.48%), obstructive uropathy in 4 patients (13.79%), vasculitis in 2 patients (6.9%) and hemolytic uremic syndrome (HUS) in 1 (3.45%) patient. There were 11 surgical complications (34.48%): 2 cases of arterial thrombosis, 3 cases of urinary fistula, 3 of lymphocele, 1 of venous thrombosis, urinoma and perineal collection. The follow-up time was 15.84 ± 12.19 months. Graft survival at 12, 24, and 40 months was 89.29%, 77.16% and 77.16%, respectively. Conclusion: Surgical complications and graft survival in pediatric renal transplantation in our series did not differ from other published series.
Cite this paper: R. Sanchez, R. Loza, C. Loza and L. Zegarra, "Surgical Complications and Evolution of Grafts in Children with Renal Transplantation at Cayetano Heredia National Hospital," Open Journal of Nephrology, Vol. 3 No. 3, 2013, pp. 124-127. doi: 10.4236/ojneph.2013.33023.

[1]   T. Kalblea, M. Lucanb, G. Nicitac, R. Sellsd, F. J. Burgos, M. Wieselet, et al., “Eau Guidelines on Renal Transplantation,” European Urology, Vol. 47, No. 2, 2005, pp. 156-166. doi:10.1016/j.eururo.2004.02.009

[2]   S. P. McDonald and J. C. Craig, “Long-Term Survival of Children with End-Stage Renal Disease,” The New England Journal of Medicine, Vol. 350, 2004, pp. 2654-2662. doi:10.1056/NEJMoa031643

[3]   B. A. Warady, D. Herbert, E. K. Sullivan, et al., “The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study,” Pediatric Nephrology, Vol. 11, No. 1, 1997, pp. 49-64. doi:10.1007/s004670050232

[4]   J. M. Palacios, P. Rosati, E. Lagos, P. Hevia, S. Rodríguez, O. Jiménez, I. Turu and K. Cuevas, “Pediatric Renal Transplant: The Experience of a Center,” Chilean Review in Surgery, Vol. 57, 2005, pp. 483-488

[5]   A. Guardiola, F. Sánchez, L. Gimeno, et al., “Urological Complications in the Renal Transplant. Study in 250 Cases,” Actas Urológicas Espanolas, Vol. 25, No. 9, 2001, pp. 628-636. doi:10.1016/S0210-4806(01)72688-5

[6]   M. Medeiros, B. Romero, S. Valverde, R. Delgadillo, G. Varela and R. Munoz, “Pediatric Renal Transplant,” Revista de Investigacion Clinica, Vol. 57, No. 2, 2005, pp. 230-236.

[7]   A. E. Da Silveira, M. de Almeida, W. Cosenza, A. C. Amarante, R. de Menezes and E. Schulz, “Renal Transplant in Children: Analytical Study in 25 Cases,” Revista Cirugia Infantil, Vol. 6, No. 4, 1996, pp. 172-176.

[8]   V. Zúniga and L. álvarez, “Pediatric Renal Transplantation in the South Central Specialty Services Hospital (HC SAE) from PEMEX (México),” Mexican Nephrology, Vol. 22, No. 2, 2001, pp. 75-82.

[9]   F. Cano and P. Rosati, “Pediatric Renal Transplant. A Decade of Multicentric Experience,” Revista Chilena de Pediatria, Vol. 72, No. 6, 2001, pp. 504-515.

[10]   O. Salvatierra, “Pediatric Renal Transplantation,” Transplantation Proceedings, Vol. 31, No. 4, 1999, pp. 1787-1788. doi:10.1016/S0041-1345(99)00168-2

[11]   R. El Atat, A. Derouiche, S. Guellouz, T. Gargah, R. Lakhoua and M. Chebil, “Surgical Complications in Pediatric and Adolescent Renal Transplantation,” Saudi Journal of Kidney Diseases and Transplantation, Vol. 21, 2010, p. 251.

[12]   J. Barba, A. Rincón, E. Tolosa, L. Romero, D. Rosell, J. E. Robles, et al., “Surgical Complications in Renal Transplantations and Its Influence in the Survival of the Graft,” Actas Urológicas Espanolas, Vol. 34, No. 3, 2010, pp. 266-273. doi:10.1016/S2173-5786(10)70059-7

[13]   S. P. Lapointe, M. Charbit, D. Jan, S. Lortat-Jacob, J. L. Michel, D. Beurton, et al., “Urological Complications after Renal Transplantation Using Ureter Ureteral Anastomosis in Children,” Journal of Urology, Vol. 166, No. 3, 2001, pp. 1046-1048. doi:10.1016/S0022-5347(05)65916-2

[14]   Latin American Pediatric Nephrology Association, et al., “Latin American Registry of Pediatric Renal Transplantation 2004-2008,” Pediatric Transplantation, Vol. 14, No. 6, 2010, pp. 701-708. doi:10.1111/j.1399-3046.2010.01331.x

[15]   P. Fentes, B. Parra, T. Caamano, et al., “Post Renal Transplant Surgical Complications. Study in 185 Cases,” Actas Urológicas Espanolas, Vol. 29, No. 6, 2005, pp. 578-586. doi:10.1016/S0210-4806(05)73300-3

[16]   E. Barboza, “Advances in Surgery in the Last 30 Years,” Revista Diagnostico, Vol. 47, No. 3, 2008, pp. 13-16.

[17]   R.M. No 568-2007/MINSA, “The Pilot Program is Created Renal Transplants from the Ministry of Health,” El Peruano, 15 July 2007, 349116.

[18]   S. Irtan, A. Maisin, V. Baudouin, Y. Nivoche, R. Azoulay, E. Jacqz-Aigrain, A. El Ghoneimi and Y. Aigrain, “Renal Transplantation in Children: Critical Analysis of Age Related Surgical Complications,” Pediatric Transplantation, Vol. 14, 2010, pp. 512-519.