IJOC  Vol.3 No.3 , September 2013
Convenient Cleavage Reaction of 1-Acylhydantoin to Amide
ABSTRACT
A cleavage reaction of 1-acylhydantoin by an amine in tetrahydrofuran at elevated temperature provided the corre-sponding amide and hydantoin in high yield. It was found that the addition of diethylaluminum chloride accelerated the cleavage reaction rate. The amide yield depended on the steric hindrance of the amine.

Cite this paper
J. Yamaguchi, K. Abe and T. Narushima, "Convenient Cleavage Reaction of 1-Acylhydantoin to Amide," International Journal of Organic Chemistry, Vol. 3 No. 3, 2013, pp. 194-197. doi: 10.4236/ijoc.2013.33025.
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