Analytical expressions of the concentrations of substrate and product in enzyme inhibition process

Sankaranarayanan  Muthukumar; Lakshmanan  Rajendran

doi:10.4236/ns.2013.59129

Sankaranarayanan Muthukumar, Lakshmanan Rajendran

Abstract: The initial and boundary value problem in enzyme reactions mechanism for inhabitation process is discussed. Approximate analytical expressions for the concentrations of substrate and product are presented. Approximate analytical solutions of non-linear reaction equations containing non-linear terms related to enzymatic reaction mechanism are solved using Homotopy perturbation method. The relevant analytical expression for the substrate and product concentration profiles is discussed in terms of dimensionless reaction diffusion parameters α, β, γE, and γS. Numerical solution is also obtained using Matlab program. Our analytical expression compared with numerical estimation and good agreement is noted.

Keywords: Initial and Boundary Value Problems; Enzyme Kinetics; Non-Linear Reaction Equations; Homotopy Perturbation Method; Michaelis-Menten Kinetics

Cite this paper: Muthukumar, S. and Rajendran, L. (2013) Analytical expressions of the concentrations of substrate and product in enzyme inhibition process. Natural Science, 5, 1047-1055. doi: 10.4236/ns.2013.59129.

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