Family tree and population: Distinction and similarity of the analysis on example of hemophilia
ABSTRACT
On the basis of Hardy-Weinberg law the distinction in the philosophy of the description of a family tree and a population is considered. With the help of introduction of the equivalent constant mutagen factor both in a family tree and in a population, the analysis of hemophilia is led. Influence of selection at presence of hemophilia is considered. On the basis of idea of Danforth and Haldane about the balance mutagenesis and selection at presence of hemophilia, the inter-relation of selection parameter and the equivalent constant mutagen factor is found. It is shown, that dynamics of development of hemophilia in a family tree and in population are similar.
Cite this paper
Volobuev, A. , Romanchuk, P. and Malishev, V. (2013) Family tree and population: Distinction and similarity of the analysis on example of hemophilia. Natural Science, 5, 979-986. doi: 10.4236/ns.2013.59119.
Volobuev, A. , Romanchuk, P. and Malishev, V. (2013) Family tree and population: Distinction and similarity of the analysis on example of hemophilia. Natural Science, 5, 979-986. doi: 10.4236/ns.2013.59119.
References
[1] von E. Libbert, H. (1982) Kompendium der allgemeinen biologie. VEB Gustav Ficher Verlag, Jena, 438 p. [2] Vogel, F. and Motulsky, A. (1990) Human genetics. 1, 310 p, 2, 380 p. Springer-Verlag, Berlin. [3] Volobuev, A.N. and Petrov, E.S. (2011) Modelling of the populating development of the genome in the radiation of the environment. Natural Science, 3, 1029-1033. doi:10.4236/ns.2011.312128 [4] Volobuev, A.N., Romanchuk, P.I. and Malishev, V.K. (2013) About one form of writing of the Hardy-Weinberg law. Natural Science, 5, 724-728. doi:10.4236/ns.2013.56089 [5] Ayala, F. and Kiger Jr., J. (1984) Modern genetics. V. 3. The Benjamin/Cummings Publishing Company, Inc. Cali fornia, 335 p. [6] Li, C.C. (1976) First course in population genetics. The Boxwood Press Pacific Grove, California, 556 p.
[1] von E. Libbert, H. (1982) Kompendium der allgemeinen biologie. VEB Gustav Ficher Verlag, Jena, 438 p. [2] Vogel, F. and Motulsky, A. (1990) Human genetics. 1, 310 p, 2, 380 p. Springer-Verlag, Berlin. [3] Volobuev, A.N. and Petrov, E.S. (2011) Modelling of the populating development of the genome in the radiation of the environment. Natural Science, 3, 1029-1033. doi:10.4236/ns.2011.312128 [4] Volobuev, A.N., Romanchuk, P.I. and Malishev, V.K. (2013) About one form of writing of the Hardy-Weinberg law. Natural Science, 5, 724-728. doi:10.4236/ns.2013.56089 [5] Ayala, F. and Kiger Jr., J. (1984) Modern genetics. V. 3. The Benjamin/Cummings Publishing Company, Inc. Cali fornia, 335 p. [6] Li, C.C. (1976) First course in population genetics. The Boxwood Press Pacific Grove, California, 556 p.