Hair loss is one of the most common complaints among all patients consulting a dermatologist and is usually associated with severe psychological disturbances, distress and symptoms of depression. [1-3]. It can be temporary or long lasting. Diagnosis of hair loss is based on detailed clinical history, physical exam, clinical diagnostic tests, laboratory testing, and scalp biopsy, which may be necessary to confirm some diagnoses. This article presents an overview of the most common clinical causes of hair loss and provides updated information on the current available therapeutic options for these disorders.
 J. V. Schmitt, C. F. Ribeiro, F. H. Souza, E. B. Siqueira and F. R. Bebber, “Hair Loss Perception and Symptoms of Depression in Female Outpatients Attending a General Dermatology Clinic,” Anais Brasileiros de Dermatologia, Vol. 87, No. 3, 2012, pp. 412-417. doi:10.1590/S0365-05962012000300010
 S. B. Shrivastava, “Diffuse Hair Loss in an Adult Female: Approach to Diagnosis and Management,” Indian Journal of Dermatology, Venereology and Leprology, Vol. 75, No. 1, 2009, pp. 20-28. doi:10.4103/0378-6323.45215
 M. B. Chartier, D. M. Hoss and J. M .Grant-Kels, “Approach to the Adult Female Patient with Diffuse Nonscarring Alopecia,” Journal of the American Academy of Dermatology, Vol. 47, No. 6, 2002, pp. 809-818. doi:10.1067/mjd.2002.128771
 H. H. Celik, H. Tore, S. Tunali, I. Tatar and M. M. Aldur, “Light and Scanning Electron Microscopic Examination of Hair in Griscelli Syndrome,” Saudi Medical Journal, Vol. 28, No. 8, 2007, pp. 1275-1277.
 V. V. Smith, G. Anderson, M. Malone and N. J. Sebire “Light Microscopic Examination of Scalp Hair Samples as an Aid in the Diagnosis of Pediatric Disorders: Retrospective Review of More Than 300 Cases from a Single Center,” Journal of Clinical Pathology, Vol. 58, No. 12, 2005, pp. 1294-1298. doi:10.1136/jcp.2005.027581
 K. A Adya, A.C Inamadar, A. Palit, R. Shivanna and N. S Deshmukh, “Light Microscopy of the Hair: A Simple Tool to ‘Untangle’ Hair Disorders,” International Journal of Trichology, Vol. 3, No. 1, 2011, pp. 46-56. doi:10.4103/0974-7753.82124
 M. Kimura-Ueki, Y. Oda, J. Oki, A. Komi-Kuramochi, E. Honda, M. Asada, M. Suzuki and T. Imamura, “Hair Cycle Resting Phase is Regulated by Cyclic Epithelial FGF18 Signaling,” Journal of Investigative Dermatology, Vol. 132, No. 5, 2012, pp. 1338-1345. doi:10.1038/jid.2011.490
 R. Sinclair, M. Patel, T. L. Dawson Jr., A. Yazdabadi, L. Yip, A. Perez and N. W. Rufaut, “Hair Loss in Women: Medical and Cosmetic Approaches to Increase Scalp Hair Fullness,” British Journal of Dermatology, Vol. 165, Suppl. 3, 2011, pp. 12-18. doi:10.1111/j.1365-2133.2011.10630.x
 H. Paterson, J. Clifton, D. Miller, J. Ashton and M. Harrison-Woolrych, “Hair Loss with Use of the Levonor- gestrel Intrauterine Device,” Contraception, Vol. 76, No. 4, 2007, pp. 306-309. doi:10.1016/j.contraception.2007.06.015
 F. M. Delamere, M. J. Sladden, H. M. Dobbins and J. Leonardi-Bee, “Interventions for Alopecia Areata,” Cochrane Database of Systematic Reviews, No. 2, 2008, Article ID: CD004413. doi:10.1002/14651858.CD004413.pub2
 M. J. García-Hernández, S. Ruiz-Doblado, A. RodriguezPichardo and F. Camacho, “Alopecia Areata, Stress and Psychiatric Disorders: A Review,” The Journal of Dermatology, Vol. 26, No. 10, 1999, pp. 625-632.
 S. Ruiz-Doblado, A. Carrizosa and M. J. García-Hernández, “Alopecia Areata: Psychiatric Comorbidity and Adjustment to Illness,” International Journal of Dermatology, Vol. 42, No. 6, 2003, pp. 434-437. doi:10.1046/j.1365-4362.2003.01340.x
 H. Khalaf, H. Negmi, G. Hassan, M. Al-Sebayel, “Postoperative Alopecia Areata: Is Pressure-Induced Ischemia the Only Cause to Blame?” Transplantation Proceedings, Vol. 36, No. 7, 2004, pp. 2158-2159. doi:10.1016/j.transproceed.2004.08.126
 I. R. Kim, J. Cho, E. K. Choi, I. G. Kwon, Y. H. Sung, J. E. Lee, S. J. Nam and J. H. Yang, “Perception, Attitudes, Preparedness and Experience of Chemotherapy-Induced Alopecia among Breast Cancer Patients: A Qualitative Study,” Asian Pacific Journal of Cancer Prevention, Vol. 13, No. 4, 2012, pp. 1383-1388. doi:10.7314/APJCP.2012.13.4.1383
 N. Shoenfeld, O. Rosenberg, M. Kotler and P. N. Dannon, “Tricotillomania: Pathopsychology Theories and Treatment Possibilities,” The Israel Medical Association Journal, Vol. 14, No. 2, 2012, pp. 125-129.
 C. A. Flessner, V. S. Knopik and J. McGeary, “Hair Pulling Disorder (Trichotillomania): Genes, Neurobiology, and a Model for Understanding Impulsivity and Compulsivity,” Psychiatry Research, Vol. 199, No. 3, 2012, pp. 151-158. doi:10.1016/j.psychres.2012.03.039
 M. E. Franklin, C. A. Flessner, D. W. Woods, N. J. Keuthen, J. C. Piacentini, P. Moore, et al., “The Child and Adolescent Trichotillomania Impact Project: Descriptive Psychopathology, Comorbidity, Functional Impairment, and Treatment Utilization,” Journal of Developmental and Behavioral Pediatrics, Vol. 29, No. 6, 2008, pp. 493-500. doi:10.1097/DBP.0b013e31818d4328
 C. D. Labouliere and E. A. Storch, “Pediatric Trichotillomania: Clinical Presentation, Treatment, and Implications for Nursing Professionals,” Journal of Pediatric Nursing, Vol. 27, No. 3, 2012, pp. 225-232. doi:10.1016/j.pedn.2011.01.028
 E. A. Olsen, K. B. Reed, P. B. Cacchio and L. Caudill, “Iron Deficiency in Female Pattern Hair Loss, Chronic Telogen Effluvium, and Control Groups,” Journal of the American Academy of Dermatology, Vol. 63, No. 6, 2010, pp. 991-999. doi:10.1016/j.jaad.2009.12.006
 R. Paus, V. A. Botchkarev, N. V. Botchkareva, L. Mecklenburg, T. Luger and A. Slominski, “The Skin POMC System (SPS). Leads and Lessons from the Hair Follicle,” Annals of the New York Academy of Sciences, Vol. 885, 1999, pp. 350-363. doi:10.1111/j.1749-6632.1999.tb08690.x
 P. C. Arck, B. Handjiski, E. Hagen, R. Joachim, B. F. Klapp and R. Paus, “Indications for a ‘Brain-Hair Follicle Axis (BHA)’: Inhibition of Keratinocyte Proliferation and Up-Regulation of Keratinocyte Apoptosis in Telogen Hair Follicles by Stress and Substance P,” FASEB Journal, Vol. 15, No. 13, 2001, pp. 2536-2538.
 A. Tosi, C. Misciali, B. M. Piraccini, A. M. Peluso and F. Bardazzi, “Drug-Induced Hair Loss and Hair Growth. Incidence, Management and Avoidance,” Drug Safety, Vol. 10, No. 4, 1994, pp. 310-317. doi:10.2165/00002018-199410040-00005
 E. A. Olsen, F. E. Dunlap, T. Funicella, J. A. Koperski, J. M. Swinehart, E. H. Tschen and R. J. Trancik, “A Randomized Clinical Trial of 5% Topical Minoxidil versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men,” Journal of the American Academy of Dermatology, Vol. 47, No. 3, 2002, pp. 377-385. doi:10.1067/mjd.2002.124088
 E. Arca, G. A?ikg?z, H. B. Ta?tan, O. K?se and Z. Kurumlu, “An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia,” Dermatology, Vol. 209, No. 2, 2004, pp. 117-125. doi:10.1159/000079595
 M. Iorizzo, C. Vincenzi, S. Voudouris, B. M. Piraccini and A. Tosti, “Finasteride Treatment of Female Pattern Hair Loss,” Archives of Dermatology, Vol. 142, No. 3, 2006, pp. 298-302. doi:10.1001/archderm.142.3.298
 D. Rathnayake and R. Sinclair, “Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss,” Dermatologic Clinics, Vol. 28, No. 3, 2010, pp. 611-618. doi:10.1016/j.det.2010.03.011
 J. D. Peereboom-Wynia, A. H. Van der Willigen, T. Van Joost and E. Stolz, “The Effect of Cyproterone Acetate on Hair Roots and Hair Shaft Diameter in Androgenetic Alopecia in Females,” Acta Dermato-Venereologica, Vol. 69, No. 5, 1989, pp. 395-398.
 R. Sinclair, M. Wewerinke and D. Jolley, “Treatment of Female Pattern Hair Loss with Oral Antiandrogens,” British Journal of Dermatology, Vol. 152, No. 3, 2005, pp. 466-473. doi:10.1111/j.1365-2133.2005.06218.x
 K. H. Chang, S. Rojhirunsakool and L. J. Goldberg, “Treatment of Severe Alopecia Areata with Intralesional Steroid Injections,” Journal of Drugs in Dermatology, Vol. 8, No. 10, 2009, pp. 909-912.
 A. Tosti, B. M. Piraccini, M. Pazzaglia and C. Vincenzi, “Clobetasol Propionate 0.05% under Occlusion in the Treatment of Alopecia Totalis/Universalis,” Journal of the American Academy of Dermatology, Vol. 49, No. 1, 2003, pp. 96-98. doi:10.1067/mjd.2003.423
 C. J. Van den Hurk, M. Peerbooms, L. V. van de Poll-Franse, J. W. Nortier, J. W. Coebergh and W. P. Breed, “Scalp Cooling for Hair Preservation and Associated Characteristics in 1411 Chemotherapy Patients—Results of the Dutch Scalp Cooling Registry,” Acta Oncologica, Vol. 51, No. 4, 2012, pp. 497-504. doi:10.3109/0284186X.2012.658966
 P. K. Auvinen, U. A. M?h?nen, K. M. Soininen, P. K. Paananen, P. H. Ranta-Koponen, I. E. Saavalainen, R. T. Johansson, M. Duvic, et al., “The Effectiveness of a Scalp Cooling Cap in Preventing Chemotherapy-Induced Alopecia,” Tumori, Vol. 96, No. 2, 2010, pp. 271-275.
 P. J. Hesketh, D. Batchelor, M. Golant, G. H. Lyman, N. Rhodes and D. Yardley, “Chemotherapy-Induced Alopecia: Psychosocial Impact and Therapeutic Approaches,” Supportive Care in Cancer, Vol. 12, No. 8, 2004, pp. 543-549. doi:10.1007/s00520-003-0562-5
 W. E. Minichiello, R. L. O’Sullivan, D. Osgood-Hynes and L. Baer, “Trichotillomania: Clinical Aspects and Treatment Strategies,” Harvard Review of Psychiatry, Vol. 1, No. 6, 1994, pp. 336-344. doi:10.3109/10673229409017100
 M. Moeinvaziri, P. Mansoori, K. Holakooee, Z. S. Naraghi and A. Abbasi, “Iron Status in Diffuse Telogen Hair Loss among Women,” Acta Dermatovenerologica Croatica, Vol. 17, No. 4, 2009, pp. 279-284.
 V. Boccaletti, E. Zendri, G. Giordano, L. Gnetti and G. De Panfilis, “Familial Uncombable Hair Syndrome: Ultrastructural Hair Study and Response to Biotin,” Pediatric Dermatology, Vol. 24, No. 3, 2007, pp. E14-E16. doi:10.1111/j.1525-1470.2007.00385.x
 W. B. Shelley and D. Shelley, “Uncombable Hair Syndrome: Observations on Response to Biotin and Occurrence in Siblings with Ectodermal Dysplasia,” Journal of the American Academy of Dermatology, Vol. 13, No. 1, 1985, pp. 97-102. doi:10.1016/S0190-9622(85)70150-8