Dendritic cyclophane tetramer and octamer
were prepared by aminolysis of succinimidyl ester derivative of tetraaza[22.214.171.124]paracyclophane
with the corresponding poly(amidoamine) dendrimers as a scaffold, followed by removal
of the protecting groups. The present cyclophane tetramer and octamer showed
enhanced guest-binding affinities toward fluorescent guests such as 6-p-toluidinonaphthalene-2-sulfonate and
6-anilinonaphthalene-2-sulfonate, in comparison with those of monocyclic
cyclophane, reflecting multivalency effects in macrocycles.
Cite this paper
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 The calculations were carried out by Using Macromodel 7.5 Software.
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