Laser induced clot formation in blood treated by EDTA

Balsam M.  Mirdan

doi:10.4236/ns.2013.57096

Balsam M. Mirdan

Abstract: Patients under systemic (ethylenediaminetetraacetic acid) EDTA are at risk of hemorrhage for any accidental trauma even the superficial ones. This research is a trial to use 980 nm wavelength laser light to provide coagulation for such patients in a local region without collateral thermal damage. Material and Method: 980 nm Diode laser operating in a continuous mode (CW) was incident on human blood treated with EDTA inDurhamtubes. The used parameters were (2.25, 3, 3.75 and 6.75) W output power for variable exposure times (1, 3, 9 and 27) s. Results: A homogenous clot was performed at 4327.84 J/cm2 deposited energy density with the absence of any thermal stress in the blood. Conclusion: 980 nm laser wavelength provides a local photochemical bond break of the anticoagulant enhancing blood coagulation for medically compromised patients.

Keywords: 980 nm Laser; Blood Clot; Laser Tissue Interaction; Photochemical Interaction

Cite this paper: Mirdan, B. (2013) Laser induced clot formation in blood treated by EDTA. Natural Science, 5, 796-799. doi: 10.4236/ns.2013.57096.

References

[1] Brummel, K.E., Paradis, S.G., Butenas, S. and Mann, K.G. (2002) Thrombin functions during tissue factor-induced blood coagulation. Blood, 100, 148-152. doi:10.1182/blood.V100.1.148

[2] Haslett, C., Chilvers, E.R., Boon, N.A. and Hunter, J.A. (2002) Davidson’s principles and practice of medicine. 19th Edition, Churchill, Livingstone, 200.

[3] Pal, G.K. and Pal, P. (2005) Brainstem auditory evoked potential. In: Text Book of Practical Physiology, 2nd Edition, Orient Longman, Chennai, 8.

[4] Bernhoft, R.A. (2012) Mercury toxicity and treatment: A review of the literature. Journal of Environmental and Public Health, 2012, 460508. doi:10.1155/2012/460508

[5] Spencer, N.C.O., Sunday, J.J., Erifeta, O.K., Georgina, O., Agbor, A.A., Esosa U.S. and Jenevieve, O. (2011) Comparative stabilizing effects of some anticoagulants on fasting blood glucose of diabetics and non-diabetics, determined by spectrophotometry (glucose oxidase). Asian Journal of Medical Sciences, 3, 234-236.

[6] Sharma, R.N. and Pancholi, S.S. (2011) Oral iron chelators: A new avenue for the management of thalassemia major. Journal of Current Pharmaceutical Research, 1, 1-7.

[7] Uhl, H.S.M., Dysko, R.C. and Clair, R.W. St. (1992) EDTA reduces liver cholesterol content in cholesterol-fed rabbits. Atherosclerosis, 96, 181-188.

[8] Baran, E.J., Wagner, C.C. and Torre, M.H. (2002) Synthesis and characterization of EDTA complexes useful for trace elements supplementation. Journal of the Brazilian Chemical Society, 13, 576-582.

[9] Wagner, C.C. and Baran, E.J. (2010) Vibrational spectra of two Fe(III)/EDTA complexes useful for iron supplementation. Spectrochimica Acta Part, 75, 807-810. doi:10.1016/j.saa.2009.11.059

[10] David, L.R. (2006) Handbook of chemistry and physics. Physical constants of organic components. 87th Edition, 244/483.

[11] Mirdan, B.M. (2012) Laser clot formation of the dental sockets after teeth extraction. Iraqi Journal of Laser, 11B, 56-60.

[12] Johansson, A., Conta, A.V., Weick, K., Winter, S. and Sroka, R. (2009) Temperature dynamics in blood during light application at 980 and 1470 nm. Medical Laser Application, 24, 140-141. doi:10.1016/j.mla.2009.02.039

[13] Niemz, M.H. (2007) Laser-tissue interactions fundamentals and applications. 2nd Edition, Springer Verlag, 145 200.