WJNST  Vol.3 No.3 , July 2013
The Utilization of Accelerators to Analyze some Human Hard Tissues from Sudan
ABSTRACT

This study deals with an overview of the biomedical projects performed at iThemba LABS, particularly in relation to the spatial distribution of trace metals in hard human tissues from disadvantaged Sudanese communities, such as kidney stone concretions, teeth and hair, undertaken at the iThemba LABS Nuclear Microprobe (NMP) facility. Relevant information about the ion beam techniques used for material characterization was discussed. The Particle Induced X-ray Emission (PIXE) technique was used to investigate the elemental composition of human hard tissues on a microscopic scale with the elemental mapping; complementary ion beam techniques are used to provide information on the major and minor components. Analysis of teeth sections by μ-PIXE showed that the levels of trace elements were enriched and/or depleted, this may associated with leaching and/or erosive processes. On the other hand the characterization of kidney stone concretions by μ-PIXE showed a marked difference of individuals from different region within Sudan.


Cite this paper
M. Eisa, C. Pineda-Vargas, S. Salah, S. Naidoo and J. Conradie, "The Utilization of Accelerators to Analyze some Human Hard Tissues from Sudan," World Journal of Nuclear Science and Technology, Vol. 3 No. 3, 2013, pp. 87-90. doi: 10.4236/wjnst.2013.33015.
References
[1]   R. Pankhurst, “The Ethiopian Borderlands,” Red Sea Press, Lawrenceville, 1997.

[2]   C. M. Hogan, “Painted Hunting Dog: Lycaon Pictus,” GlobalTwitcher.com, 2009.

[3]   C. A. Pineda and M. Peisach, “Micro-Analysis of Kidney Stones Sequentially Excreted from a Single Patient,” Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 85, No. 1-4, 1994, pp. 896-900. doi:10.1016/0168-583X(94)95945-5

[4]   C. A. Pineda, A. L. Rodgers, V. M. Prozesky and W. J. Prybylowicz, “Microanalysis of Calcium-Rich Human Kidney Stones at the NAC Nuclear Microprobe,” Cell and Molecular Biology, Vol. 42, No. 1, 1996, pp. 119-126.

[5]   C. A. Pineda-Vargas, A. L. Rodger and M. E. Eisa, “Nuclear Microscopy of Human Kidney Stones, Comparison between Two Population Groups,” Radiation Physics and Chemistry, Vol. 30, No. 3, 2004, pp. 947-950. doi:10.1016/j.radphyschem.2004.04.125

[6]   D. Ronald, “The Proton Microprobe Applications in the Biomedical Fields,” CRC Press, Boca Raton, 2000.

[7]   W. J. Przybylowicz, J. Mesjasz-Przybylowicz, C. A. Pineda, C. L.Churms, C. G. Ryan, V. M. Prozesky, R. Frei, J. P. Slabbert, J. Padayachee and W. U. Reimold, “Elemental Mapping Using Proton-Induced X-rays,” X-ray Spectrometry, Vol. 30, No. 3, 2001, p. 156. doi:10.1002/xrs.474

[8]   V. M. Prozesky, C. A. Pineda, J. Mesjasz-Przybylowicz, W. J. Przybylowicz, C. L. Churms, K. A. Springhorn, Ph. Moretto, C. Michelet, U. Chikte and P. Wenzel, “The Biological Research Programme of the Nuclear Microprobe at the National Accelerator Centre, Faure,” Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 161-163, 2000, pp. 852-859. doi:10.1016/S0168-583X(99)00895-2

[9]   C. A. Pineda-Vargas, S. Naidoo and M. E. M. Eisa, “Nuclear Microanalysis of Tooth Enamel from a Community in the Western Cape, South Africa,” Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 260, No. 1, 2007, pp. 190-193. doi:10.1016/j.nimb.2007.02.023

[10]   C. G. Ryan, E. Van Achterbergh and C. J. Yeats, T. T. Win and G. Cripps, “Quantitative PIXE Trace Element Imaging of Minerals Using the New CSIRO-GEMOC Nuclear Microprobe,” Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 189, No. 1-4, 2002, pp. 400-407. doi:10.1016/S0168-583X(01)01098-9

[11]   C. G. Ryan, “Quantitative Trace Element Imaging Using PIXE and the Nuclear Microprobe,” International Journal of Imaging Systems and Technology, Vol. 11, No. 4, 2000, pp. 219-230. doi:10.1002/ima.1007

[12]   C. G. Ryan, E. van Achterbergh, C. J. Yeats, S. L. Drieberg, G. Mark, B. M. McInnes, T. T. Win, G. Cripps and G. F. Suter, “Quantitative, High Sensitivity, High Resolution, Nuclear Microprobe Imaging of Fluids, Melts and Minerals,” Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 188, No. 1-4, 2002, pp. 18-27. doi:10.1016/S0168-583X(01)01003-5

[13]   C. A. Pineda-Vargas and M. E. M. Eisa, “Analysis of Human Hair Cross Sections from Two Different Population Groups by Nuclear Microscopy,” Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 268, No. 11-12, 2010, pp. 2164-2167. doi:10.1016/j.nimb.2010.02.041

[14]   C. G. Ryan and D. R. Cousens, “Geo-PIXE II Quantitative PIXE Trace Element Imaging and Analysis,” CSIRO Exploration and Mining, North Ryde, 2002

[15]   SPSS, “Data Analysis Software System, Version 15,” 2006. www.spss.com.

[16]   FAO, “Sudan Nutrition Profile—Food and Nutrition Division,” 2005.

 
 
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