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 FNS  Vol.4 No.7 A , July 2013
Acute Toxicity and Genotoxic Evaluation of Metlin® and Metlos® (Organic Agave Fructans)
Abstract: The aim of the study was to contribute to the information on agave soluble fibers since research has been focused on chicory fiber but not in agave products; thus we assess the acute toxicity and genotoxicity of two organic and high purity dietary soluble fibers from agave, Metlin? and Metlos?. We performed an acute toxicity assay in Hsd:ICR mice and Hsd:Wistar rats and an in vivo genotoxic test. Results showed that there are no deaths at any doses or genotoxicity, so it can be concluded that these products are non-toxic, at the administrated doses and none showed a cytotoxic, clastogenic or aneuploidic effect.
Cite this paper: M. Gracia, M. Tinoco, H. Rivera, B. Sanchez, P. Tapia, L. Altamirano, R. Romero and O. García, "Acute Toxicity and Genotoxic Evaluation of Metlin® and Metlos® (Organic Agave Fructans)," Food and Nutrition Sciences, Vol. 4 No. 7, 2013, pp. 106-112. doi: 10.4236/fns.2013.47A013.
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