The duodenal leiomyosarcoma is a rare tumor. Its location in the duodenum makes diagnosis difficult and often delayed. Surgical treatment is not consensual because it must take into account anatomical imperatives which vary depending on the duodenal portion and oncological requirements that are not currently well known especially with regard to the utility of lymphadenectomy. We report 2 cases of leiomyosarcomas located at the angle of Treitz. This location is exceptional and only few cases were reported in the literature. From these 2 new cases and a review of the literature, we analyze the clinical features, diagnosis and treatment of duodenal leiomyosarcoma.
 M. Elabsi, M. Amraoui, M. Elouannani, M. Echarrab, et al., “Duodenal Leiomyosarcoma Revealed by Gastrointestinal Hemorrhage,” La Presse Médicale, Vol. 36, No. 11, 2007, pp. 1585-1588. doi:10.1016/j.lpm.2007.03.039
 M. Pitcher, A. Colfor, E. Moskovic and J. M. Thomas, “Duodenal Leiomyosarcoma as a Cause of Retroperitoneal Sepsis,” European Journal of Surgical Oncology, Vol. 21, No. 1, 1995, pp. 85-86. doi:10.1016/S0748-7983(05)80075-7
 A. Watanabe, D. Korenaga, H. Baba, et al., “Long Survival of a Woman with a Huge Leiomyosarcoma of the Duodenum after Pancreaticoduodenectomy and Transverse Colectomy: A Case Report,” Surgery, Vol. 108, No. 1, 1990, pp. 110-113.
 S. Pedrazzoli, C. Sperti, C. Militello, A. Chiappetta, et al., “Duodenal Leiomyosarcoma and Its Multiple Recurrences: Good Surgical Result after Three Years of FollowUp,” The Italian Journal of Surgical Sciences, Vol. 14, No. 4, 1984, pp. 321-326.
 M. Fleet, A. F. Mellon, J. A. Lee, et al., “Duodenal Leiomyosarcoma Presenting with Iron Deficiency Anemia,” Journal of Pediatric Surgery, Vol. 29, No. 12, 1994, pp. 1601-1603. doi:10.1016/0022-3468(94)90233-X
 S. H. uzuki and A. Yasui, “Pancreas-Sparing Duodenectomy for a Huge Leiomyosarcoma in the Third Portion of the Duodenum,” Journal of Hepato-Biliary Pancreatic Surgery, Vol. 6, No. 4, 1999, pp. 414-417. doi:10.1007/s005340050142
 N. Kawano, M. Ryu, T. Kinoshita, M. Konishi, et al., “Segmental Resection of the Duodenum for Treating Leiomyosarcoma Associated with von Recklinghausen’s Disease: A Case Report,” Japanese Journal of Clinical Oncology, Vol. 25, No. 3, 1995, pp. 109-112.
 Y. N. Ho, Y. P. Leong, A. S. Sakijan, M. Swaminathan and K. Sarvananthan, “Duodenal Leiomyosarcoma: A Report of a Rare and Aggressive Tumour,” Singapore Medical Journal, Vol. 33, No. 3, 1992, pp. 297-298.