Vaginal adenosis is one of the rare diseases of the vagina, and almost all
patients are asymptomatic. We report a case of spontaneous vaginal adenosis,
which caused vesicovaginal fistula. Case Presentation: Our patient was a
25-year-old Japanese woman. She was admitted to our hospital, and her chief
complaint was continuous urine flow from the vagina. We found a tumor with a
vesicovaginal fistula in her vagina. Subsequent cytological analysis of vaginal
smears showed a normal vaginal mucosa. The patient underwent tumor resection
and a fistula patch. Pathological diagnosis was adenosis of the vagina, even
though the patient had no known history of intrauterine diethylstilbestrol
exposure or Müllerian developmental abnormalities. Conclusion: The clinical
course of our case was a malignant tumor, which invasively bored a hole in the
vaginal wall forming a vesicovaginal fistula, even though it was a benign lesion.
Therefore, overzealous treatment should be avoided in this case.
Cite this paper
Mariya, T. , Suzuki, T. , Habata, S. , Matsuura, M. , Suzuki, M. , Tanaka, R. and Saito, T. (2013) Development of vesicovaginal fistula caused by vaginal adenosis: A case report. Open Journal of Obstetrics and Gynecology, 3, 435-437. doi: 10.4236/ojog.2013.35079.
 Narayanan, P., Nobbenhuis, M., Reynolds, K.M., Sahdev, A., Reznek, R.H. and Rockall, A.G. (2009) Fistulas in malignant gynecologic disease: Etiology, imaging, and management. RadioGraphics, 29, 1073-1083.
 Kranl, C., Zelger, B., Kofler, H., Heim, K., Sepp, N. and Fritsch, P. (1998) Vulvar and vaginal adenosis. British Journal of Dermatology, 139, 128-131.
 Uehara, T., Onda, T., Sasajima, Y., Sawada, M. and Kasamatsu, T. (2010) A case of vaginal clear cell adenocarcinoma complicated with congenital anomalies of the genitourinary tract and metanephric remnant without prenatal diethylstilbestrol exposure. Journal of Obstetrics and Gynaecology Research, 36, 681-685.
 Talia, K.L., Scurry, J., Manolitsas, T. and McCluggage, W.G. (2012) Primary vaginal mucinous adenocarcinoma of gastric type arising in adenosis: A report of 2 cases, 1 associated with uterus didelphys. International Journal of Gynecological Pathology, 31, 184-191.
 Stafl, A., Mattingly, R.F., Foley, D.V. and Fetherston, W.C. (1974) Clinical diagnosis of vaginal adenosis. Obstetrics and Gynecology, 43, 118-128.