last few years, condensed thienopyrimidine derivatives have received
considerable attention. The therapeutic importance of thienopyrimidines
prompted us to synthesize some of spiro(benzothieno[2,3-d]pyrimidine-4-one) derivatives. Some of the novel benzothino-pyrimidine
derivatives 3a, 9b,
10b, 11a, 11b, and 11c showed considerable potent
anti-inflammatory and analgesic activity of superior G.I.T. safety profile in
experimental rats in comparing to indomethacin and tramadol as reference drugs.
Cite this paper
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