OJIM  Vol.3 No.2 , June 2013
Diagnostic dilemma: metastatic bone malignancy or primary hyperparathyroidism with brown tumor
Abstract: Multiple osteolytic lesions are usually associated with metastatic involvement of the bone. However metabolic bone diseases should also take their place in differential diagnosis. Here, we describe a primary hyperparathyroidism case with full-blown osteolytic lesions wich was diagnosed at first sight with having metastatic bone involvement. PET CT scan and laboratory results excluded a metastatic bone malignancy. Elevated serum calcium of 13.16 mg/dl, decreased serum phoshorus of 1.4 mg/dl and high intact-PTH level of 1054.7 pg/ml pointed out primary hyperparathyroidism. Sonographic examination revealed two adenomas of 2.9 × 3.3 mmand 3.3 ×2.7 mmin the left superior and right inferior parathyroid glands, respectively. Scintigraphy confirmed the presence of adenoma on the left.
Cite this paper: Hatipoglu, E. , Eskazan, A. , Celik, O. , Kantarci, F. and Kadioglu, P. (2013) Diagnostic dilemma: metastatic bone malignancy or primary hyperparathyroidism with brown tumor. Open Journal of Internal Medicine, 3, 60-62. doi: 10.4236/ojim.2013.32015.

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