Purpose: The purpose of the present study was to
compare the effect of intramuscular masseter administration of
methylprednisolone using a split-mouth design, as a single 20-mg dose, after
removal of impacted lower third molars. Patients and Methods: A non-blind,
cross-over, comparative, non-randomized, clinical trial was planned. The sample
was composed of 32 patients requiring extraction under local anesthesia of
two lower bony impacted mandibular third molars. The difficulty of extraction
was similar in all cases. The patients received 20 mg of methylprednisolone
injected into the masseter muscle via the intrabuccal approach, immediately
after suturing of the surgical wound on the right side. The left side received
no intramuscular corticoid. Evaluations were made of postoperative pain and
swelling. Results: A total of 32 subjects requiring surgical removal of two
impacted mandibular third molars under local anesthesia were included in the
present study. The patients administered methylprednisolone showed superior
results after surgery in terms of pain and facial swelling parameters using
self-evaluation, with statistically significant differences versus the control-side
(p < 0.05). The results obtained show that 20 mg of methylprednisolone
injected into the masseter muscle in the immediate postoperative period reduces
swelling and pain. Conclusions: Injection of methylprednisolone is an
effective therapeutic strategy to reduce swelling and pain after surgical
removal of impacted lower third molars. It offers a simple, safe, painless,
noninvasive, and cost effective therapeutic option for moderate and severe
Cite this paper
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