CRCM  Vol.2 No.2 , May 2013
Renal cell carcionoma with synchronous metastases to the bladder and lung
ABSTRACT

Renal cell carcinoma can metastasize to virtually any organ, yet synchronous metastasis to the bladder is extremely rare. A 77-year-old woman presented with gross hematuria. Abdominal and chest computed tomography showed a bilateral renal masses, bladder dome mass, and multiple lung metastasis. Transurethral resection of the bladder tumor and sonography guided renal biopsy were performed. Both pathology diagnoses were clear cell renal cell carcinoma. Targeted therapy using pazopanib was administered to the patient without surgical resection of primary tumors and metastatic lung lesions. Herein, we report the synchronous metastasis of renal cell carcinoma to the bladder and lung.


Cite this paper
Jang, W. , Hwang, I. , Hwang, E. , Jung, S. , Kwon, D. and Choi, C. (2013) Renal cell carcionoma with synchronous metastases to the bladder and lung. Case Reports in Clinical Medicine, 2, 97-99. doi: 10.4236/crcm.2013.22026.
References
[1]   Marshall, F.F., Stewart, A.K. and Menck, H.R. (1997) The national cancer database: Report on kidney cancers. Cancer, 80, 2167-2174. doi:10.1002/(SICI)1097-0142(19971201)80:11<2167::AID-CNCR18>3.0.CO;2-X

[2]   Uygur, M.C., Özen, H.A., Sungur, A. and Remzi, D. (1994) A solitary and synchronous metastasis of renal cell carcinoma to the bladder. International Urology and Nephrology, 26, 529-533. doi:10.1007/BF02767654

[3]   Shiraishi K., Mohri J., Inoue R., et al. (2003) Metastatic renal cell carcinoma to the bladder 12 years after radical nephrectomy. International Journal of Urology, 10, 453-455. doi:10.1046/j.1442-2042.2003.00652.x

[4]   Boorjian, S.A., Crispen, P.L., Lohse, C.M., et al. (2008) The impact of temporal presentation on clinical and pathological outcomes for patients with sporadic bilateral renal masses. European Urology, 54, 855-863. doi:10.1016/j.eururo.2008.04.079

[5]   Dogra, P., Kumar, A. and Singh, A. (2007) An unusual case of Von Hipple Lindau (VHL) syndrome with bilateral multicentric renal cell carcinoma with synchronous solitary urinary bladder metastasis. International Urology and Nephrology, 39, 11-14. doi:10.1007/s11255-006-6656-5

[6]   Abeshouse, B.S. (1956) Metastasis to ureters and urinary bladder from renal carcinoma: Report of two cases. Journal of the International College, 25, 117-126.

[7]   Négrier, S., Escudier, B., Gomez, F., et al. (2002) Prognostic factors of survival and rapid progression in 782 patients with metastatic renal carcinomas treated by cytokines: A report from the Groupe Francais d’Immunothérapie. Annals of Oncology, 13, 1460-1468. doi:10.1093/annonc/mdf257

[8]   Raviv, S., Eggener, S.E., Williams, D.H., et al. (2002) Long-term survival after “drop metastases” of renal cell carcinoma to the bladder. Urology, 60, 697. doi:10.1016/S0090-4295(02)01846-0

[9]   Dogra, P., Kumar, A. and Singh, A. (2007) An unusual case of Von Hipple Lindau (VHL) syndrome with bilateral multicentric renal cell carcinoma with synchronous solitary urinary bladder metastasis. International Urology and Nephrology, 39, 11-14. doi:10.1007/s11255-006-6656-5

[10]   Swanson, D.A. and Liles, A. (1982) Bladder metastasis: A rare cause of hematuria in renal cell carcinoma. Journal of Surgical Oncology, 20, 80-82. doi:10.1002/jso.2930200204

 
 
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