Physiopathology of parotid cell energetics
Affiliation(s)
Laboratory of Experimental Hormonology, Université Libre de Bruxelles, Brussels, Belgium.
Laboratory of Experimental Hormonology, Université Libre de Bruxelles, Brussels, Belgium.
ABSTRACT
Attention was recently drawn to the production of D-glucose by salivary glands and its concentration in the saliva of both normal and diabetic subjects. Likewise, the identity and expression of selected transporters involved in the handling of the hexose by salivary glands were recently investigated in both normal and diabetic rats. In consideration of this information, the present report aims at providing an integrated review on the physiopathology of parotid cell energetics.
Attention was recently drawn to the production of D-glucose by salivary glands and its concentration in the saliva of both normal and diabetic subjects. Likewise, the identity and expression of selected transporters involved in the handling of the hexose by salivary glands were recently investigated in both normal and diabetic rats. In consideration of this information, the present report aims at providing an integrated review on the physiopathology of parotid cell energetics.
Cite this paper
Jurysta, C. , Sener, A. and Malaisse, W. (2013) Physiopathology of parotid cell energetics. Advances in Biological Chemistry, 3, 159-163. doi: 10.4236/abc.2013.32020.
Jurysta, C. , Sener, A. and Malaisse, W. (2013) Physiopathology of parotid cell energetics. Advances in Biological Chemistry, 3, 159-163. doi: 10.4236/abc.2013.32020.
References
[1] Jurysta, C., Bulur, N., Oguzhan, B., Satman, I., Yilmaz, T.M., Malaisse, W.J. and Sener, A. (2009) Salivary glucose concentration and excretion in normal and diabetic subjects. Journal of Biomedicine and Biotechnology, 2009, 1-16. [2] Jurysta, C., Nicaise, C., Cetik, S., Louchami, K., Malaisse, W.J. and Sener, A. (2012) Glucose transport by acinar cells in rat parotid glands. Cellular Physiology and Biochemistry, 29, 325-330. doi:10.1159/000338487 [3] Jurysta, C., Nicaise, C., Giroix, M.-H., Cetik, S., Malaisse, W.J. and Sener, A. (2013) Comparison of GLUT1, GLUT2, GLUT4 and SGLT1 mRNA-expression in the salivary glands and six other organs of control, streptozotocin-induced and Goto-Kakizaki diabetic rats. Cellular Physiology and Biochemistry, 31, 34-43. doi:10.1159/000343347 [4] Blocklet, D., Jijakli, H., Sener, A., Schoutens, A. and Malaisse, W.J. (1998) 99mTc-sesta-(2-methoxy-isobutylisonitrile) uptake by pancreatic islets, parotid cells, and mammary carcinoma cells. Endocrine, 9, 113-117. doi:10.1385/ENDO:9:1:113 [5] Ramirez, R., Courtois, P., Ladrière, L., Kadiata, M.M., Sener, A. and Malaisse, W.J. (2001) Uptake of D-mannoheptulose by rat erythrocytes, hepatocytes and parotid cells. International Journal of Molecular Medicine, 8, 37-42. [6] Scruel, O., Vanhoutte, C., Sener, A. and Malaisse, W.J. (1998) Interference of D-mannoheptulose with D-glucose phosphorylation, metabolism and functional effects: Comparison between liver, parotid cells and pancreatic islets. Molecular and Cellular Biochemistry, 187, 113120. doi:10.1023/A:1006812300200 [7] Malaisse, W.J., Kadiata, M.M., Scruel, O. and Sener, A. (1998) Esterification of D-mannoheptulose confers to the heptose inhibitory action on D-glucose metabolism in parotid cells. Biochemistry and Molecular Biology International, 44, 625-633. [8] Sener, A., Scruel, O., Louchami, K., Jijakli, H. and Malaisse, W.J. (1999) Inhibition of glucose-induced insulin release by 3-O-methyl-D-glucose: Enzymatic, metabolic and cationic determinants. Molecular and Cellular Biochemistry, 194, 133-145. doi:10.1023/A:1006955617718 [9] Courtois, P., Sener, A. and Malaisse, W.J. (2001) D-mannoheptulose phosphorylation by hexokinase isoenzymes. International Journal of Molecular Medicine, 7, 359-363. [10] Sener, A., Giroix, M.-H. and Malaisse, W.J. (2002) Underestimation of D-glucose utilization as judged from the conversion of D-[3-3H]glucose to 3HOH. Diabetologia, 45, 1274-1280. doi:10.1007/s00125-002-0907-5 [11] Giroix, M.-H., Jijakli, H., Courtois, P., Zhang, Y., Sener, A. and Malaisse, W.J. (2006) Fructokinase activity in rat liver, ileum, parotid gland, pancreas, pancreatic islet, B and non-B islet cell homogenates. International Journal of Molecular Medicine, 17, 517-522. [12] Scruel, O., Sener, A. and Malaisse, W.J. (1999) Hexose metabolism in pancreatic islets: Effect of D-glucose upon D-fructose metabolism. Molecular and Cellular Biochemistry, 197, 209-216. doi:10.1023/A:1006910201767 [13] Giroix, M.-H., Scruel, O., Ladrière, L., Sener, A., Portha, B. and Malaisse, W.J. (1999) Metabolic and secretory interactions between D-glucose and D-fructose in islets from GK rats. Endocrinology, 140, 5556-5565. doi:10.1210/en.140.12.5556 [14] Ladrière, L., Louchami, K., Laghmich, A., MalaisseLagae, F. and Malaisse, W.J. (2001) Labeling of pancreatic glycogen by D-[U-14C]glucose in hyperglycemic rats. Endocrine, 14, 383-397. doi:10.1385/ENDO:14:3:383 [15] Malaisse, W.J., Damhaut, P., Malaisse-Lagae, F., Ladrière, L., Olivares, E. and Goldman, S. (2000) Fate of 2deoxy-2-[18F]fluoro-D-glucose in control and diabetic rats. International Journal of Molecular Medicine, 5, 525-532. [16] Malaisse, W.J., Damhaut, P., Ladrière, L. and Goldman, S. (2000) Fate of 2-deoxy-2-[18F]fluoro-D-glucose in hyperglycemic rats. International Journal of Molecular Medicine, 6, 549-552. [17] Sener, A., Jijakli, H., Zahedi Asl, S., Courtois, P., Yates, A.P., Meuris, S., Best, L.C. and Malaisse, W.J. (2007) Possible role of carbonic anhydrase in pancreatic islets: Enzymatic, secretory, metabolic, ionic, and electrical aspects. American Journal of Physiology, Endocrinology and Metabolism, 292, E1624-E1630. doi:10.1152/ajpendo.00631.2006 [18] Sener, A., Courtois, P., Meuris, S. and Malaisse, W.J. (2008) Carbonic anhydrase activity in parotid cells and pancreatic islets from Goto-Kakizaki rats. Metabolic and Functional Research on Diabetes, 1, 26-27. [19] Youssef, R., Malaisse, W.J., Courtois, P. and Sener, A. (2003) Alteration of α-amylase secretion from rat parotid cells in the absence of extracellular bicarbonate. International Journal of Molecular Medicine, 12, 199-200. [20] Delporte, C., Malaisse, W.J., Jurysta, C., Portois, L., Sener, A. and Carpentier, Y.A. (2007) Altered fatty acid pattern of phospholipids and triglycerides in the submandibular gland of ϖ-depleted rats. European Journal of Oral Sciences, 115, 103-110. [21] Jurysta, C., Sener, A., Carpentier, Y.A. and Malaisse, W.J. (2006) Phospholipid and triglyceride content and fatty acid pattern in the submandibular gland of rats depleted in long-chain polyunsaturated ϖ3 fatty acids. Acta Physicologica, 187, 2758-2761.
[1] Jurysta, C., Bulur, N., Oguzhan, B., Satman, I., Yilmaz, T.M., Malaisse, W.J. and Sener, A. (2009) Salivary glucose concentration and excretion in normal and diabetic subjects. Journal of Biomedicine and Biotechnology, 2009, 1-16. [2] Jurysta, C., Nicaise, C., Cetik, S., Louchami, K., Malaisse, W.J. and Sener, A. (2012) Glucose transport by acinar cells in rat parotid glands. Cellular Physiology and Biochemistry, 29, 325-330. doi:10.1159/000338487 [3] Jurysta, C., Nicaise, C., Giroix, M.-H., Cetik, S., Malaisse, W.J. and Sener, A. (2013) Comparison of GLUT1, GLUT2, GLUT4 and SGLT1 mRNA-expression in the salivary glands and six other organs of control, streptozotocin-induced and Goto-Kakizaki diabetic rats. Cellular Physiology and Biochemistry, 31, 34-43. doi:10.1159/000343347 [4] Blocklet, D., Jijakli, H., Sener, A., Schoutens, A. and Malaisse, W.J. (1998) 99mTc-sesta-(2-methoxy-isobutylisonitrile) uptake by pancreatic islets, parotid cells, and mammary carcinoma cells. Endocrine, 9, 113-117. doi:10.1385/ENDO:9:1:113 [5] Ramirez, R., Courtois, P., Ladrière, L., Kadiata, M.M., Sener, A. and Malaisse, W.J. (2001) Uptake of D-mannoheptulose by rat erythrocytes, hepatocytes and parotid cells. International Journal of Molecular Medicine, 8, 37-42. [6] Scruel, O., Vanhoutte, C., Sener, A. and Malaisse, W.J. (1998) Interference of D-mannoheptulose with D-glucose phosphorylation, metabolism and functional effects: Comparison between liver, parotid cells and pancreatic islets. Molecular and Cellular Biochemistry, 187, 113120. doi:10.1023/A:1006812300200 [7] Malaisse, W.J., Kadiata, M.M., Scruel, O. and Sener, A. (1998) Esterification of D-mannoheptulose confers to the heptose inhibitory action on D-glucose metabolism in parotid cells. Biochemistry and Molecular Biology International, 44, 625-633. [8] Sener, A., Scruel, O., Louchami, K., Jijakli, H. and Malaisse, W.J. (1999) Inhibition of glucose-induced insulin release by 3-O-methyl-D-glucose: Enzymatic, metabolic and cationic determinants. Molecular and Cellular Biochemistry, 194, 133-145. doi:10.1023/A:1006955617718 [9] Courtois, P., Sener, A. and Malaisse, W.J. (2001) D-mannoheptulose phosphorylation by hexokinase isoenzymes. International Journal of Molecular Medicine, 7, 359-363. [10] Sener, A., Giroix, M.-H. and Malaisse, W.J. (2002) Underestimation of D-glucose utilization as judged from the conversion of D-[3-3H]glucose to 3HOH. Diabetologia, 45, 1274-1280. doi:10.1007/s00125-002-0907-5 [11] Giroix, M.-H., Jijakli, H., Courtois, P., Zhang, Y., Sener, A. and Malaisse, W.J. (2006) Fructokinase activity in rat liver, ileum, parotid gland, pancreas, pancreatic islet, B and non-B islet cell homogenates. International Journal of Molecular Medicine, 17, 517-522. [12] Scruel, O., Sener, A. and Malaisse, W.J. (1999) Hexose metabolism in pancreatic islets: Effect of D-glucose upon D-fructose metabolism. Molecular and Cellular Biochemistry, 197, 209-216. doi:10.1023/A:1006910201767 [13] Giroix, M.-H., Scruel, O., Ladrière, L., Sener, A., Portha, B. and Malaisse, W.J. (1999) Metabolic and secretory interactions between D-glucose and D-fructose in islets from GK rats. Endocrinology, 140, 5556-5565. doi:10.1210/en.140.12.5556 [14] Ladrière, L., Louchami, K., Laghmich, A., MalaisseLagae, F. and Malaisse, W.J. (2001) Labeling of pancreatic glycogen by D-[U-14C]glucose in hyperglycemic rats. Endocrine, 14, 383-397. doi:10.1385/ENDO:14:3:383 [15] Malaisse, W.J., Damhaut, P., Malaisse-Lagae, F., Ladrière, L., Olivares, E. and Goldman, S. (2000) Fate of 2deoxy-2-[18F]fluoro-D-glucose in control and diabetic rats. International Journal of Molecular Medicine, 5, 525-532. [16] Malaisse, W.J., Damhaut, P., Ladrière, L. and Goldman, S. (2000) Fate of 2-deoxy-2-[18F]fluoro-D-glucose in hyperglycemic rats. International Journal of Molecular Medicine, 6, 549-552. [17] Sener, A., Jijakli, H., Zahedi Asl, S., Courtois, P., Yates, A.P., Meuris, S., Best, L.C. and Malaisse, W.J. (2007) Possible role of carbonic anhydrase in pancreatic islets: Enzymatic, secretory, metabolic, ionic, and electrical aspects. American Journal of Physiology, Endocrinology and Metabolism, 292, E1624-E1630. doi:10.1152/ajpendo.00631.2006 [18] Sener, A., Courtois, P., Meuris, S. and Malaisse, W.J. (2008) Carbonic anhydrase activity in parotid cells and pancreatic islets from Goto-Kakizaki rats. Metabolic and Functional Research on Diabetes, 1, 26-27. [19] Youssef, R., Malaisse, W.J., Courtois, P. and Sener, A. (2003) Alteration of α-amylase secretion from rat parotid cells in the absence of extracellular bicarbonate. International Journal of Molecular Medicine, 12, 199-200. [20] Delporte, C., Malaisse, W.J., Jurysta, C., Portois, L., Sener, A. and Carpentier, Y.A. (2007) Altered fatty acid pattern of phospholipids and triglycerides in the submandibular gland of ϖ-depleted rats. European Journal of Oral Sciences, 115, 103-110. [21] Jurysta, C., Sener, A., Carpentier, Y.A. and Malaisse, W.J. (2006) Phospholipid and triglyceride content and fatty acid pattern in the submandibular gland of rats depleted in long-chain polyunsaturated ϖ3 fatty acids. Acta Physicologica, 187, 2758-2761.