M. Fujisawa, R. Haramaki, H. Miyazaki, T. Imaizumi and S. Okuda, “Role of Lipoprotein (a) and TGF-β1 in Atherosclerosis of Hemodialysis Patients,” Journal of the American Society of Nephrology, Vol. 11, No. 10, 2000, pp. 1889-1895.
 A. Ito, P. S. Tsao, S. Adimoolam, M. Kimoto, T. Ogawa and J. P. Cooke, “Novel Mechanism for Endothelial Dysfunction: Dysregulation of Dimethylarginine Dimethylaminohydrolase,” Circulation, Vol. 99, No. 24, 1999, pp. 3092-3095.
 R. M. J. Palmer, A. G. Ferrige and S. Moncada, “Nitric Oxide Release Accounts for the Biological Activity of Endothelium-Derived Relaxing Factor,” Nature, Vol. 327, 1987, pp. 524-526. doi:10.1038/327524a0
 A. J. Pope, K. Karrupiah, P. N. Kearns, Y. Xia and A. J. Cardounel, “Role of Dimethylarginine Dimethylaminohydrolases in the Regulation of Endothelial Nitric Oxide Production,” Journal of Biological Chemistry, Vol. 284, No. 51, 2009, pp. 35338-35347.
 C. Antoniades, C. Shirodaria, P. Leeson, A. Antonopoulos, N. Warrick, T. Van-Assche, et al., “Association of Plasma Asymmetrical Dimethylarginine (ADMA) with Elevated Vascular Superoxide Production and Endothelial Nitric Oxide Synthase Uncoupling: Implications for Endothelial Function in Human Atherosclerosis,” European Heart Journal, Vol. 30, No. 9, 2009, pp. 1142-1150.
 R. Maas, K. Quitzau, E. Schwedhelm, L. Spieker, W. Rafflenbeul, A. Steenpass, et al., “Asymmetrical Dimethylarginine (ADMA) and Coronary Endothelial Function in Patients with Coronary Artery Disease and Mild Hypercholesterolemia,” Atherosclerosis, Vol. 191, No. 1, 2007, pp. 211-219.
 F. Palm, M. L. Onozato, Z. Luo and C. S. Wilcox, “Dimethylarginine Dimethylaminohydrolase (DDAH): Ex- pression, Regulation, and Function in the Cardiovascular and Renal Systems,” Heart and Circulatory Physiology: American Journal of Physiology, Vol. 293, No. 6, 2007, pp. H3227-H3245.
 R. Ryan, J. Thornton, E. Duggan, E. McGovern, M. J. O’Dwyer, A. W. Ryan, et al., “Gene Polymorphism and Requirement for Vasopressor Infusion after Cardiac Surgery,” Annals of Thoracic Surgery, Vol. 82, No. 3, 2006, pp. 895-901.
 M. O’Dwyer, F. Dempsey, V. Crowley, D. Kelleher, R. McManus and T. Ryan, “Septic Shock Is Correlated with Asymmetrical Dimethyl Arginine Levels, Which May Be Influenced by a Polymorphism in the Dimethylarginine Dimethylaminohydrolase II Gene: A Prospective Observational Study,” Critical Care, Vol. 10, No. 5, 2006, p. R139.
 M. Thaha, Widodo, M. Yogiantoro and Y. Tomino, “Intravenous N-Acetylcysteine during Hemodialysis Reduces Asymmetric Dimethylarginine Levels in End-Stage Renal Disease Patients,” Clinical Nephrology, Vol. 69, No. 1, 2008, pp. 24-32.
 M. Thaha, M. Yogiantoro and Y. Tomino, “Intravenous N-Acetylcysteine during Haemodialysis Reduces the Plasma Concentration of Homocysteine in Patients with End-Stage Renal Disease,” Clinical Drug Investigation, Vol. 26, 2006, pp. 195-202.
 L. Jones, C. Tran, J. Leiper, A. Hingorani and P. Vallance, “Common Genetic Variation in a Basal Promoter Element Alters DDAH 2 Expression in Endothelial Cells,” Biochemical and Biophysical Research Communications, Vol. 310, No. 3, 2003, pp. 836-843.
 R. Maas, J. Erdmann, N. Luneburg, J. Stritzke, E. Schwedhelm, C. Meisinger, et al., “Polymorphisms in the Promoter Region of the Dimethylarginine Dimethylaminohydrolase 2 Gene Are Associated with Prevalence of Hypertension,” Pharmacological Research, Vol. 60, No. 6, 2009, pp. 488-493.
 J. Wang, A. Sim, X. Wang, C. Salonikas, D. Naidoo and D. Wilcken, “Relations between Plasma Asymmetric Dimethylarginine (ADMA) and Risk Factors for Coronary Disease,” Atherosclerosis, Vol. 184, No. 2, 2006, pp. 383-388.
 J. T. Kielstein, S. R. Salpeter, S. M. Bode-Boeger, J. P. Cooke and D. Fliser, “Symmetric Dimethylarginine (SDMA) as Endogenous Marker of Renal Function—A Meta-Analysis,” Nephrology Dialysis Transplantation, Vol. 21, No. 9, 2006, pp. 2446-2451.
 V. Achan, M. Broadhead, M. Malaki, G. Whitley, J. Leiper, R. MacAllister, et al., “Asymmetric Dimethylarginine Causes Hypertension and Cardiac Dysfunction in Humans and Is Actively Metabolized by Dimethylarginine Dimethylaminohydrolase,” Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 23, No. 8, 2003, pp. 1455-1459.
 M. Feng, L. Liu, Z. Guo and Y. Xiong, “Gene Transfer of Dimethylarginine Dimethylaminohydrolase-2 Improves the Impairments of DDAH/ADMA/NOS/NO Pathway in Endothelial Cells Induced by Lysophosphatidylcholine,” European Journal of Pharmacology, Vol. 584, No. 1, 2008, pp. 49-56.
 H. Dayoub, V. Achan, S. Adimoolam, J. Jacobi, M. C. Stuehlinger, B.-Y. Wang, et al., “Dimethylarginine Dimethylaminohydrolase Regulates Nitric Oxide Synthesis,” Circulation, Vol. 108, No. 24, 2003, pp. 3042-3047.
 J. Leiper, J. Santa Maria, A. Chubb, R. MacAllister, I. Charles, G. Whitley, et al., “Identification of Two Human Dimethylarginine Dimethylaminohydrolases with Distinct Tissue Distributions and Homology with Microbial Arginine Deiminases,” Biochemical Journal, Vol. 341, 1999, pp. 209-214. doi:10.1042/0264-6021:3430209
 A. Tojo, W. Welch, V. Bremer, M. Kimoto, K. Kimura, M. Omata, et al., “Colocalization of Demethylating Enzymes and NOS and Functional Effects of Methylarginines in Rat Kidney,” Kidney International, Vol. 52, No. 6, 1997, pp. 1593-1601.
 M. E. Widlansky, N. Gokce, J. F. Keaney Jr. and J. A. Vita, “The Clinical Implications of Endothelial Dysfunction,” Journal of the American College of Cardiology, Vol. 42, No. 7, 2003, pp. 1149-1160.
 C. Tran, M. Fox, P. Vallance and J. Leiper, “Chromosomal Localization, Gene Structure, and Expression Pattern of DDAH 1: Comparison with DDAH 2 and Implications for Evolutionary Origins,” Genomics, Vol. 68, No. 1, 2000, pp. 101-105.
 A. Ito, K. Egashira, T. Narishige, K. Muramatsu and A. Takeshita, “Renin-Angiotensin System Is Involved in the Mechanism of Increased Serum Asymmetric Dimethylarginine in Essential Hypertension,” Japanese Circulation Journal, Vol. 65, No. 9, 2001, pp. 775-778.
 F. Perticone, A. Sciacqua, R. Maio, M. Perticone, R. Maas, R. H. Boger, et al., “Asymmetric Dimethylarginine, L-Arginine, and Endothelial Dysfunction in Essential Hypertension,” Journal of the American College of Cardiology, Vol. 46, No. 3, 2005, pp. 518-523.
 J. Leiper and P. Vallance, “New Tricks from an Old Dog : Nitric Oxide-Independent Effects of Dimethylarginine Dimethylaminohydrolase,” Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 26, No. 7, 2006, pp. 1419-1420.
 T. Ogawa, M. Kimoto and K. Sasaoka, “Purification and Properties of a New Enzyme, NG,NG-Dimethylarginine Dimethylaminohydrolase, from Rat Kidney,” Journal of Biological Chemistry, Vol. 264, No. 17, 1989, pp. 10205-10209.
 J. Jacobi, K. Sydow, G. von Degenfeld, Y. Zhang, H. Dayoub, B. Wang, et al., “Overexpression of Dimethylarginine Dimethylaminohydrolase Reduces Tissue Asymmetric Dimethylarginine Levels and Enhances Angiogenesis,” Circulation, Vol. 111, No. 11, 2005, pp. 1431- 1438.
 C. Smith, G. Birdsey, S. Anthony, F. Arrigoni, J. Leiper and P. Vallance, “Dimethylarginine Dimethylaminohydrolase Activity Modulates ADMA Levels, VEGF Expression, and Cell Phenotype,” Biochemical and Biophysical Research Communications, Vol. 308, No. 4, 2003, pp. 984-989.
 V. Achan, C. T. L. Tran, F. Arrigoni, G. S. J. Whitley, J. M. Leiper and P. Vallance, “All-Trans-Retinoic Acid Increases Nitric Oxide Synthesis by Endothelial Cells,” Circulation Research, Vol. 90, No. 7, 2002, pp. 764-769.
 R. H. BÖger, S. M. Bode-BÖger, K. Sydow, D. D. Heistad and S. R. Lentz, “Plasma Concentration of Asymmetric Dimethylarginine, an Endogenous Inhibitor of Nitric Oxide Synthase, Is Elevated in Monkeys with Hyperhomocyst(e)inemia or Hypercholesterolemia,” Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 20, No. 6, 2000, pp. 1557-1564.