ABSTRACT Coronary artery disease (CAD) is
a leading cause of mortality and morbidity in developed countries, although
percutaneous coronary intervention and coronary artery bypass grafting have developed
recently. Appropriate diagnosis will improve the prevention, treatment, and
care of all patients. We could diagnose only calcification in the coronary
arteries with the past computed tomography. Recently, multislice computed
tomography has been already accepted as an efficient non-invasive tool for the
detectionof coronary artery stenosis. We get to estimate the
coronary artery stenosis with cardiac computed tomography.We discuss the usefulness of
cardiac computed tomography for the risk stratification ofcoronary artery atherosclerosis.
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R. Wake, H. Iida, H. Ogata, H. Takeshita, T. Kusuyama, H. Kohno, S. Shimodozono, K. Shimada and M. Yoshiyama, "Cardiac Computed Tomography for the Diagnosis of Coronary Artery Atherosclerosis," International Journal of Clinical Medicine, Vol. 4 No. 3, 2013, pp. 183-189. doi: 10.4236/ijcm.2013.43032.
 R. O. Bonow, L. A. Smaha, S. C. Smith Jr., G. A. Mensah and C. Lenfant, “World Heart Day 2002: The International Burden of Cardiovascular Disease: Responding to the Emerging Global Epidemic,” Circulation, Vol. 106, No. 13, 2002, pp. 1602-1605.
 T. M. Bashore, E. R. Bates, P. B. Berger, et al., “American College of Cardiology/Society for Cardiac Angiography and Interventions Clinical Expert Consensus Document on Cardiac Catheterization Laboratory Standards. A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents,” Journal of the American College of Cardiology, Vol. 37, No. 8, 2001, pp. 2170-2214.
 G. N. Hounsfield, “Computerized Transverse Axial Scanning (Tomography). 1. Description of System,” British Journal of Radiology, Vol. 46, No. 552, 1973, pp. 1016-1022. doi:10.1259/0007-1285-46-552-1016
 U. Hoffmann, J. T. Nagurney, F. Moselewski, et al., “Coronary Multidetector Computed Tomography in the Assessment of Patients with Acute Chest Pain,” Circulation, Vol. 114, No. 21, 2006, pp. 2251-2260.
 A. J. Taylor, M. Cerqueira, J. M. Hodgson, et al., “ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 Appropriate Use Criteria for Cardiac Computed Tomography: A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance,” Circulation, Vol. 122, No. 21, 2010, pp. e525-e555.
 S. B. King III, S. C. Smith Jr, J. W. Hirshfeld Jr., A. K. Jacobs, D. A. Page, B. Riegel, L. G. Tarkington, C. W. Y. Hunt, H. M. Krumholz, F. G. Kushner, B. W. Lytle, R. Nishimura, R. L. Christopher, E. Buller, M. A. Creager, S. M. Ettinger, J. L. Halperin, S. A. O. Williams, S. C. Smith Jr., A. K. Jacobs, C. D. Adams, J. L. Anderson III, D. A. Morrison, W. W. O’Neill, H. V. Schaff, P. L. Whitlow, T. E. Feldman, J. W. Hirshfeld Jr, A. K. Jacobs, M. J. Kern, S. B. K. Morrison, D. O. Williams and S. C. Smith (2005 Writing Committee Members), “2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention, Writing on Behalf of the 2005 Writing Committee Evidence and Update the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Association Task Force on Practice Guidelines: 2007 Writing Group to Review New Coronary Intervention : A Report of the American College of Cardiology/American Heart,” Circulation, Vol. 117, No. 2, 2008, pp. 261-295.
 G. A. Diamond and J. S. Forrester, “Analysis of Probability as an Aid in the Clinical Diagnosis of Coronary Artery Diseases,” New England Journal of Medicine, Vol. 300, 1979, pp. 1310-1358.
 G. A. Diamond, J. S. Forrester and M. Hirsch, “Application of Conditional Probability Analysis to the Clinical Diagnosis of Coronary Artery Disease,” Journal of Clinical Investigation, Vol. 65, No. 5, 1980, pp. 1210-1221.
 D. J. Kumbhani, C. P. Ingelmo, P. Schoenhagen, R. J. Curtin, S. D. Flamm and M. Y. Desai, “Meta-Analysis of Diagnostic Efficacy of 64-Slice Computed Tomography in the Evaluation of Coronary In-Stent Restenosis,” can Journal of Cardiology, Vol. 103, No. 12, 2009, pp. 1675-1681. doi:10.1016/j.amjcard.2009.02.024
 S. Leschka, H. Alkadhi, A. Plass, et al., “Accuracy of MSCT Coronary Angiography with 64-Slice Technology: First Experience,” European Heart Journal, Vol. 26, No. 15, 2005, pp. 1482-1487. doi:10.1093/eurheartj/ehi261
 N. R. Mollet, F. Cademartiri, C. A. van Mieghem, et al., “High-Resolution Spiral Computed Tomography Coronary Angiography in Patients Referred for Diagnostic Conventional Coronary Angiography,” Circulation, Vol. 112, No. 15, 2005, pp. 2318-2323.
 G. L. Raff, M. J. Gallagher, W. W. O’Neill and J. A. Goldstein, “Diagnostic Accuracy of Noninvasive Coronary Angiography Using 64-Slice Spiral Computed Tomography,” Journal of the American College of Cardiology, Vol. 46, No. 3, 2005, pp. 552-557.
 J. M. Miller, C. E. Rochitte, M. Dewey, et al., “Diagnostic Performance of Coronary Angiography by 64-Row CT,” New England Journal of Medicine, Vol. 359, No. 22, 2008, pp. 2324-2336. doi:10.1056/NEJMoa0806576
 M. J. Budoff, D. Dowe, J. G. Jollis, et al., “Diagnostic Performance of 64-Multidetector Row Coronary Computed Tomographic Angiography for Evaluation of Coronary Artery Stenosis in Individuals without Known Coronary Artery Disease: Results from the Prospective Multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) Trial,” Journal of the American College of Cardiology, Vol. 52, No. 21, 2008, pp. 1724-1732. doi:10.1016/j.jacc.2008.07.031
 J. Datta, C. S. White, R. C. Gilkeson, et al., “Anomalous Coronary Arteries in Adults: Depiction at Multi-Detector Row CT Angiography,” Radiology, Vol. 235, No. 3, 2005, pp. 812-818. doi:10.1148/radiol.2353040314
 M. Schmid, S. Achenbach, J. Ludwig, et al., “Visualization of Coronary Artery Anomalies by Contrast-Enhanced Multi-Detector Row Spiral Computed Tomography,” International Journal of Cardiology, Vol. 111, No. 3, 2006, pp. 430-435. doi:10.1016/j.ijcard.2005.08.027
 M. J. Budoff, S. Achenbach, R. S. Blumenthal, et al., “Assessment of Coronary Artery Disease by Cardiac Computed Tomography: A Scientific Statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology,” Circulation, Vol. 114, No. 16, 2006, pp. 1761-1791.
 A. P. Burke, R. Virmani, Z. Galis, C. C. Haudenschild and J. E. Muller, “34th Bethesda Conference: Task Force #2—What Is the Pathologic Basis for New Atherosclerosis Imaging Techniques?” Journal of the American College of Cardiology, Vol. 41, No. 11, 2003, pp. 1874-1886.
 K. Pohle, D. Ropers, R. Maffert, et al., “Coronary Calcifications in Young Patients with First, Unheralded Myocardial Infarction: A Risk Factor Matched Analysis by Electron Beam Tomography,” Heart, Vol. 89, No. 6, 2003, pp. 625-658. doi:10.1136/heart.89.6.625
 P. G. O’Malley, A. J. Taylor, J. L. Jackson, T. M. Doherty and R. C. Detrano, “Prognostic Value of Coronary Electron-Beam Computed Tomography for Coronary Heart Disease Events in Asymptomatic Populations,” American Journal of Cardiology, Vol. 85, No. 8, 2000, pp. 945-948. doi:10.1016/S0002-9149(99)00906-6
 S. Achenbach, F. Moselewski, D. Ropers, et al., “Detection of Calcified and Noncalcified Coronary Atherosclerotic Plaque by Contrast-Enhanced, Submillimeter Multidetector Spiral Computed Tomography: A Segment-Based Comparison with Intravascular Ultrasound,” Circulation, Vol. 109, No. 1, 2004, pp. 14-17.
 A. W. Leber, A. Becker, A. Knez, et al., “Accuracy of 64-Slice Computed Tomography to Classify and Quantify Plaque Volumes in the Proximal Coronary System: A Comparative Study Using Intravascular Ultrasound,” Journal of the American College of Cardiology, Vol. 47, No. 3, 2006, pp. 672-677. doi:10.1016/j.jacc.2005.10.058
 A. W. Leber, A. Knez, A. Becker, et al., “Accuracy of Multidetector Spiral Computed Tomography in Identifying and Differentiating the Composition of Coronary Atherosclerotic Plaques: A Comparative Study with Intracoronary Ultrasound,” Journal of the American College of Cardiology, Vol. 43, No. 7, No. 2004, pp. 1241-1247.
 K. Pohle, S. Achenbach, B. Macneill, et al., “Characterization of Non-Calcified Coronary Atherosclerotic Plaque by Multi-Detector Row CT: Comparison to IVUS,” Atherosclerosis, Vol. 190, No. 1, 2007, pp. 174-180.
 U. Hoffmann, F. Moselewski, K. Nieman, et al., “Noninvasive Assessment of Plaque Morphology and Composition in Culprit and Stable Lesions in Acute Coronary Syndrome and Stable Lesions in Stable Angina by Multidetector Computed Tomography,” Journal of the American College of Cardiology, Vol. 47, No. 8, 2006, pp. 1655-1662. doi:10.1016/j.jacc.2006.01.041