CRCM  Vol.2 No.1 , March 2013
Lymphoid interstitial pneumonia—Another consideration for recurrent bacterial pneumonia in an HIV positive patient (A case report)
ABSTRACT

We present a 39-year-old female with HIV, medication non-compliance, and recurrences of bacterial pneumonia. She presented with a two-day bout of worsening shortness of breath, dyspnea and productive cough. A CT of the chest was notable for multi-lobular pneumonia. She underwent flexible bronchoscopy and biopsy which revealed lymphocytic interstitial pneumonitis. Conclusion: Recurrent bacterial pneumonia is a rare complication of lymphoid interstitial pneumonia (LIP) in HIV positive patients, and should be considered in the differential as a possible precipitator of recurrent pneumonia inan HIV positive patient.


Cite this paper
Persaud, K. , Harris, C. and Ramsahai, S. (2013) Lymphoid interstitial pneumonia—Another consideration for recurrent bacterial pneumonia in an HIV positive patient (A case report). Case Reports in Clinical Medicine, 2, 76-80. doi: 10.4236/crcm.2013.21021.
References
[1]   American Thoracic Society/European Respiratory Society (2002) American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. American Journal of Respiratory and Critical Care Medicine, 165, 277-304.

[2]   Swigris, J.J., Berry, G.J., Raffin, T.A. and Kuschner, W.G. (2002) Lymphoid interstitial pneumonia: A narrative review. CHEST, 122, 2150-2164. doi:10.1378/chest.122.6.2150

[3]   Lin, R.Y., Gruber, P.J., Saunders, R. and Perla, E.N. (1988) Lymphocytic interstitial pneumonitis in adult HIV infection. New York State Journal of Medicine, 88, 273-276.

[4]   Harley, W., Horton, J.M. and Corbin, R.P. (1992) Recurrent pneumococcal pneumonia in an HIV-positive patient with lymphoid interstitial pneumonitis. Southern Medical Journal, 85, 1015-1016. doi:10.1097/00007611-199210000-00022

[5]   Carrington, C.B. and Liebow, A.A. (1966). Lymphocytic interstitial pneumonia (abstract). American Journal of Pathology, 48, 36a.

[6]   Das, S. and Miller, R.F. (2003) Lymphocytic interstitial pneumonitis in HIV infected adults. Sexually Transmitted Infections, 79, 88-93. doi:10.1136/sti.79.2.88

[7]   Davies, C.W.H., Juniper, M.C., Gray, W., Gleeson, F.V., Chapel, H. and Davies, R.J.O. (2000) Lymphoid interstitial pneumonitis associated with common variable hypogammaglobulinemia treated with cyclosporin A. Thorax, 55, 88-90. doi:10.1136/thorax.55.1.88

[8]   Travis, W.D., Fox, C.H., Devaney, K.O., Weiss, L.M., O’Leary, T.J., Ognibene, F.P., Suffredini, A.F., Rosen, M.J., Cohen, M.B. and Shelhamer, J. (1992) Lymphoid pneumonitis in 50 adult patients infected with the human immunodeficiency virus: Lymphocytic interstitial pneumonitis versus nonspecific interstitial pneumonitis. Human Pathology, 23, 529-541. doi:10.1016/0046-8177(92)90130-U

[9]   Najjar, N., Gamal, A.E., Halabi, S. and Leyenson, V. (2005) A 38-year-old man with HIV Infection and sub acute onset of cough and dyspnea. CHEST, 128, 4008-4012. doi:10.1378/chest.128.6.4008

[10]   Dean, N.C., Golden, J.A., Evans, L.A., Warnock, M.L., Addison, T.E., Hopewell, P.C. and Levy, P.A. (1988) Human immunodeficiency virus recovery from bronchialveolar lavage fluid in patients with AIDS. CHEST, 93, 1176-1179. doi:10.1378/chest.93.6.1176

[11]   Dufour, V., Wislez, M., Bergot, E., Mayaud, C. and Cadranel, J. (2003) Improvement of symptomatic human immunodeficiency virus-related lymphoid interstitial pneumonia in patients receiving highly active antiretroviral therapy. Clinical Infectious Disease, 36, e127-e130. doi:10.1086/374665

[12]   Kazi, S., Cohen, P.R., Williams, F., Schempp, R. and Reveille, J.D. (1996) The diffuse infiltrative lymphocytosis syndrome: Clinical and immunogenetic features in 35 patients. AIDS, 10, 385-391. doi:10.1097/00002030-199604000-00006

[13]   Ishikawa, N., Awaya, Y., Maeda, H., Miyazaki, M., Fujitaka, K., Yamasaki, M., Kondo, K., Oguri, T., Isobe, T. and kohno, N. (2002) KL-6 as an indicator for lymphocytic interstitial pneumonia (LIP) in a human T-lymphotrophic virus type 1 (HTLV-1) carrier. Annals of Hematology, 81, 474-477. doi:10.1007/s00277-002-0465-4

[14]   Freemer, M.M. and King Jr., T.W. (2003) Lymphoplasmocytic infiltration of the lung. In: Schwarz, M.I. and King Jr., T.W., Eds, Interstitial Lung Disease, B. C. Decker, Hamilton, 827.

[15]   Macfarlane, A. and Davies, D. (1973) Diffuse lymphoid interstitial pneumonia. Thorax, 28, 768-776. doi:10.1136/thx.28.6.768

[16]   Rosewarne, D., Reynolds, J.H., Trotter, S.E. and Burge, P.S. (2008) The idiopathic interstitial pneumonias—A survival guide. Imaging, 20, 289-302.

[17]   Balestro, E., Pastore, U., Dal Farra, F., Rossi, G., Calabro, S., Polverosi, R. and Vassallo, E. (2008) A 40-year-old man with hemolytic anemia, Ig deficiency, and bilateral pulmonary infiltrates. CHEST, 133, 1517-1523.

[18]   Cao, M., Soogoor, M. and Vintch, J. (2005) Lymphocytic Interstitial Pneumonia (LIP) and Human Immunodeficiency Virus (HIV) in the modern era. CHEST, 128, 426S.

[19]   Innes, A.L., Huang, L. and Nishimura, S.L. (2004) Resolution of lymphocytic interstitial pneumonitis in an HIV infected adult after treatment with HAART. Sexually Transmitted Infections, 80, 417-418. doi:10.1136/sti.2004.009886

[20]   Ingiliz, P., Appenrodt, B., Gruenhage, F., Vogel, M., Tschampa, H., Tasci, S. and Rockstroh, J.K. (2006) Lymphoid pneumonitis as an immune reconstitution inflammatory syndrome in a patient with CD4 cell recovery after HAART initiation. HIV Medicine, 7, 411-414. doi:10.1111/j.1468-1293.2006.00389.x

 
 
Top