Acute leukemia is often associated with oral manifestations. We report an acute promyelocytic leukemia (APL) case with oral manifestations leading to the diagnosis.A 21-year-old femalevisited our hospital with complaints of gingival bleeding and swelling of the left lower wisdom tooth. The patient’s complete blood count revealed a marked increase in white blood cells and a decrease in red blood cells and an abnormal leukocyte differential, andAPL was diagnosed on the basis of bone marrow samplesin theinternal medicine department. The patient was treated with all-trans-retinoic acidcombined with chemotherapy and has maintained clinical and molecular complete remission at 12 months of follow-up.Dental professionalsshould be aware of clinical manifestations and complications associated withthese malign-nant neoplastic diseases to aid in diagnosis and subsequent treatment and management.
Cite this paper
Daisuke Saito, D. , Kobayashi, T. , Oda, Y. , Niimi, K. , Kano, H. and Saito, C. (2013) Oral manifestations of acute promyelocytic leukemia: A case report. Open Journal of Stomatology, 3, 25-27. doi: 10.4236/ojst.2013.31005.
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