OJOG  Vol.3 No.2 , March 2013
Ovarian desmoplastic small round cell tumors: Prognosis is poor! Case report
ABSTRACT

The tumor desmoplastic small round cell in women is rare. Ovarian its location is exceptional. We report a patient of 20 years, the originalNorth Africawho consulted for an increase in abdominal volume with impaired general condition. Pelvic ultrasonography and computed tomography were in favor of multiple peritoneal masses with ascites. After surgical exploration, the histological and immunohistochemical data for diagnosis small round cell desmoplastic tumor of ovarian the patient was a candidate for poly chemotherapy but she was died a month later. Diagnosis relies on histological and immunohistochemical data. The demonstration of a nonrandom translocation t (11; 22) (p13; q12) is specific for the disease. The management is multidisciplinary and combining surgery, a poly aggressive chemotherapy and radiotherapy. The prognosis remains poor.


Cite this paper
Saadi, H. , Fatmi, H. , Mamouni, N. , Errarhay, S. , Bouchikhi, C. , Amarti, A. and Banani, A. (2013) Ovarian desmoplastic small round cell tumors: Prognosis is poor! Case report. Open Journal of Obstetrics and Gynecology, 3, 235-238. doi: 10.4236/ojog.2013.32044.
References
[1]   Gerald, W.L. and Rosai, J. (1989) Desmoplastic small cell tumor with divergent differentiation. Pediatric Pathology, 9, 177-183. doi:10.3109/15513818909022347

[2]   Battisti, S., Renaudin, K., Rigaud, J., Hetet, J.F., Braud, G., Kapfer, J., et al. (2005) Tumeurs desmoplastiques à petites cellules rondes paratesticulaires. Progres En Urologie, 15, 333-336.

[3]   Chang, F. (2006) Desmoplastic small round cell tumors. Cytologic, histologic and immunihistochemical features. Archives of Pathology & Laboratory Medicine, 130, 728-732

[4]   Rais, H., El Mansouri, F., Belaabidia, B., Essadki, O., Oussehal, A. and Saif, I. (2010) Tumeur desmoplastique à petites cellules rondes paratesticulaires: A propos d’une observation avec revue de la littérature. Cancer/Radiothérapie, 14, 111-114.

[5]   Gerald W.L., Miller, H.K., Battifora, H., Miettiner, M., Silva, E.G. and Rosai, J. (1999) Intra abdominal desmoplastic Small round cell tumor. Report of 19 cases of distinctive type of high-grade polyphenotypic malignancy affecting young individuals. The American Journal of Surgical Pathology, 15, 499-513.

[6]   Roques, B., Pichon, A., De Laroche, G., Garnier, J.F. and Jacquin, J.P. (2000) Tumeurs desmoplastiques intra abdominales à petites cellules rondes: Une entité parmi les carcinoses péritonéales de l’adulte jeune. Gastroentérologie Clinique et Biologique, 24, 359-360.

[7]   Jellouli, M., Mongi, M., Krichene, I. M., Zakhama, A., Belghith, M., Jouini, R., Sahnoun, L., Rammeh, S., Harbi, A. and Nouri, A. (2003) Tumeur desmoplastique à petite cellules rondes intra abdominal de l’enfant: A propos d’une observation avec revue de la littérature. Bull Cancer, 90, 1063-1066.

[8]   Chouli, M., Viala, J., Dromain, C., Fizazi, K., Duvillard, P. and Vanel, D. (2005) Intra-abdominal desmoplastic small round cell tumors: CT findings and clinicopathological correlations in 13 cases. European Journal of Radiology, 5, 438-442. doi:10.1016/j.ejrad.2004.09.002

[9]   Kallel, R., Ayadi, L., Masmoudi, A., Makni, S., Beyrouti, I., Frikha, M. and Boudawara, T. (2008) Tumeur intraabdominale inhabituelle. Revue Medicale de Bruxelles, 29, 180-183.

[10]   Eaton, S.H. and Cendron, M.A. (2006) Primary desmoplastic small round cell tumor of the kidney in a 7-yearold girl. Journal of Pediatric Urology, 2, 52-54. doi:10.1016/j.jpurol.2005.05.008

[11]   Maliki, M., Mahassini, N., Zouaidia, F., Bernoussi, Z., Mansouri, F. and El Hachimi, A. (2004) Tumeur desmoplastique à petites cellules rondes: A case report. Revue Médicale de Liège, 59, 451-454.

[12]   Afif, H., Benouhoud, N., Aichane, A., Trombati, N. and Bouayad, Z. (2006) Métastases pulmonaires d’une tumeur desmoplastique à petites cellules rondes. Revue de Pneumologie Clinique, 62, 53-55. doi:10.1016/S0761-8417(06)75415-3

[13]   Schwartz, R.E., Gerald, W.L., Kushner, B.H., Coit, D.G., Brennan, M.F. and Laquaglia M.P. (1998) Desmoplastic small round cell tumors: Pronostic indicators and results of surgical management. Annals of Surgical Oncology, 5, 416-422. doi:10.1007/BF02303860

[14]   Kushner, B.H., Laquaglia, M.P. and Wollner, N. (1996) Desmoplastic small round cell tumor: Prolonged progression-free survival with agressive multimodality therapy. Journal of Clinical Oncology, 14, 1526-1531.

[15]   Farha, T.F., Culine, S., Lhomme, C., Duvillard, P., Terrierlacombe, M.J., Michel, G., Soulie, P., Theodore, C., Lotz, J.P. and Droz, J.P. (1996) Desmoplastic small round cell tumor. Result of a four-drug chemotherapy regimen in five adult patients. Cancer, 77, 1363-1366. doi:10.1002/(SICI)1097-0142(19960401)77:7<1363::AID-CNCR21>3.0.CO;2-Z

[16]   Goodman, K.A., Wolden, S.L., La Quaglia, M.P. and Kushner, B.H. (2002) Whole abdominopelvic radiotherapy of desmoplastic small round cell tumor. International Journal of Radiation, Oncology, Biology Physics, 54, 170-176. doi:10.1016/S0360-3016(02)02871-7

 
 
Top