Introduction: Laryngeal angioleiomyoma is a rare benign tumor of larynx with vascular
origin. We report a case of laryngeal angioleiomyoma in a 52-year-old female.
Case presentation: A 52- year-old Caucasian female was referred to our
institute with a chief compliant of severe midnight snoring. Her symptoms were
progressive and began from two years ago. There was no history of hoarseness
and laryngeal pain. The patient underwent a laryngoscopic examination and a
large mass was seen on the left aryepiglotic fold. Surface of lesion was
smooth and covered by laryngeal mucosa with no ulcer. There was a rapid
enhancing mass on left aryepiglotic fold with bulging into the left
piriformis sinus in contrast-enhanced
computed tomography. The tumor was
complicated by profuse bleeding after biopsy which was not controlled by
conventional approaches. The patient was then administered a general anesthesia
and the tumor was completely removed via laryngosurgery accompanied by left
superior thyroid artery ligation. The specimen was histopathologically compatible with laryngeal angioleiomyoma. Conclusion: Angioleiomyoma of larynx is of benign nature and rarely recurs.
However, it can be complicated by profuse bleeding on biopsy and
contrast-medium imaging should be considered before
surgical intervention to diagnose the tumor properly and prevent
Cite this paper
Rezaee, A. , Ebrahimi, L. , Sadeghipour, A. , Azimzadeh, B. and Azizian, A. (2013) Laryngeal angioleiomyoma: A case report of 52-year-old female. Case Reports in Clinical Medicine, 2, 20-23. doi: 10.4236/crcm.2013.21006.
 Anderson, T.D. and Weinstein, G.S. (2000) Recurrent angiomyoma (vascular leiomyoma) of the larynx after laser excision. Otolaryngology—Head and Neck Surgery, 123, 646-647. doi:10.1067/mhn.2000.110105
 Jun, F., Li, L., Ning, L., Yan, L., Siquan, T. and Shixi, L. (2009) Giant laryngeal angioleiomyomas: A case report with review of literature. American Journal of Otolaryngology, 30, 219-220. doi:10.1016/j.amjoto.2008.11.001
 Xu, Y., Zhou, S. and Wang, S. (2008) Vascular leiomyoma of the larynx: A rare entity. Three case reports and literature review. Journal for Oto-Rhino-Laryngology and Its Related Specialties, 70, 264-267.
 Hachisuga, T., Hashimoto, H. and Enjoji, M. (1984) Angioleiomyoma. A clinicopathologic reappraisal of 562 cases. Cancer, 54, 126-130.
 Nuutinen, J. and Syrj?nen, K. (1983) Angioleiomyoma of the larynx. Report of a case and review of the literature. Laryngoscope, 93, 941-943.
 Farman, A.G. (1975) Benign smooth muscle tumours. South African Medical Journal, 49, 1333-1340.
 Hirakawa, K., Harada, Y., Tatsukawa, T., Nagasawa, A. and Fujii, M. (1994) A case of vascular leiomyoma of the larynx. The Journal of Laryngology & Otology, 108, 593595. doi:10.1017/S0022215100127537
 Wang, C.P., Chang, Y.L. and Sheen, T.S. (2004) Vascular leiomyoma of the head and neck. Laryngoscope, 114, 661-665. doi:10.1097/00005537-200404000-00012
 Hirshoren, N., Weinberger, J.M., Neuman, T., Ilan, O. and Ben-Yaakov, A. (2010) Recurrent vascular leiomyoma of the larynx: clinical and histopathologic characteristics and treatment. Ear, Nose & Throat Journal, 89, 382-386.
 Yoo, H.J., Choi, J.A., Chung, J.H., Oh, J.H., Lee, G.K., Choi, J.Y., et al. (2009) Angioleiomyoma in soft tissue of extremities: MRI findings. American Journal of Roentgenology, 192, W291-294. doi:10.2214/AJR.07.3952
 Shibata, K. and Komune, S. (1980) Laryngeal angiomyoma (vascular leiomyoma): Clinicopathological findings. Laryngoscope, 90, 1880-1886.
 J?ckel, M.C., Martin, A. and Steiner, W. (2007) Twentyfive years’ experience with laser surgery for head and neck tumors: Report of an international symposium, G?ttingen, Germany, 2005. European Archives of Oto-RhinoLaryngology, 264, 577-585.