OJPed  Vol.3 No.1 , March 2013
National outbreak of Salmonella typhimuriumwith preference for infants
ABSTRACT

Purpose: During a large outbreak of Salmonella typhimurium (S. typhimurium) inDenmarkin 2008, a remarkable high incidence was observed among children below the age of 1 year. Therefore we performed this retrospective study to describe the epidemiology, severity and outcome among a subset of children in this age-group. Methods: Cases were identified for the years 2000-2009 through a register at the Department of Clinical Microbiology atHvidovreHospital, in theCopenhagenarea,Denmark. For hospitalized patients below 1 year with S. typhimurium, the medical record was reviewed. Results: The highest incidence for S. typhimurium was observed in 2008 with 315 cases per 100,000 among children below 1 year. In 2008 significantly more children age <6 months were admitted to the hospital compared to infants 6 - 12 months. The duration of symptoms before admittance was shorter among the infants in 2008, compared to the group consisting of infants in other years 2000- 2009 (p = 0.04). None of the children had bacteremia or meningitis, and none of the children died. Conclusion: During the S. typhimurium outbreak in 2008, the incidence was especially high among infants age under 1 year. The infants in 2008 might have been slightly more affected than other years 2000-2009.


Cite this paper
Jensen, L. , Rosenfeldt, V. and Knudsen, J. (2013) National outbreak of Salmonella typhimuriumwith preference for infants. Open Journal of Pediatrics, 3, 24-27. doi: 10.4236/ojped.2013.31005.
References
[1]   Graham, S.M. Salmonellosis in children in developing and developed countries and populations. Current Opinion in Infectious Diseases, 2002, 15, 507-512. doi:10.1097/00001432-200210000-00009

[2]   Hohmann, E.L. (2001) Nontyphoidal salmonellosis. Clinical Infectious Diseases, 32, 263-269. doi:10.1086/318457

[3]   Ethelberg, S., Wingstrand, A., Jensen, T., et al. (2008) Large outbreaks of Salmonella typhimurium infection in Denmark in 2008. Eurosurveillance, 13, p. 19023.

[4]   Ethelberg, S., Wingstrand, A., Jensen, T., et al. (2008) Large ongoing outbreak of infection with Salmonella typhimurium U292 in Denmark, February-July 2008. Eurosurveillance, 13, p. 18923.

[5]   Ethelberg, S., Molbak, K., Olsen, K.E.P. and Scheutz, F. (2009) Zoonotiske tarminfektioner 2008. Statens Serum Institute.

[6]   Statistics Denmark. http://www statistikbanken dk/statbank5a/default asp?w= 1280 2011

[7]   Cahill, S.M., Wachsmuth, I.K., Costarrica, M.L. and Ben Embarek, P.K. (2008) Powdered infant formula as a source of Salmonella infection in infants. Clinical Infectious Diseases, 46, 268-273. doi:10.1086/524737

[8]   Graham, S.M., Molyneux, E.M., Walsh, A.L., Cheesbrough, J.S., Molyneux, M.E. and Hart, C.A. (2000) Nontyphoidal Salmonella infections of children in tropical Africa. Pediatric Infectious Disease Journal, 19, 1189-1196. doi:10.1097/00006454-200012000-00016

[9]   Huang, I.F., Wagener, M.M., Hsieh, K.S., et al. (2004) Nontyphoid salmonellosis in Taiwan children: Clinical manifestations, outcome and antibiotic resistance. Journal of Pediatric Gastroenterology & Nutrition, 38, 518-523. doi:10.1097/00005176-200405000-00011

[10]   Gaffga, N.H., Barton, B.C., Ettestad, P.J., et al. (2012) Outbreak of salmonellosis linked to live poultry from a mail-order hatchery. The New England Journal of Medicine, 366, 2065-2073. doi:10.1056/NEJMoa1111818

 
 
Top