OJBIPHY  Vol.3 No.1 A , February 2013
Methods to Be Developed for Some First Applications of Mitochondrial Filamentation

The new field of mitochondrial filamentation and its first potential applications are just getting underway (1-7), following a series of pilot experiments in our laboratory over the past few decades (8-14). I should like to give a brief overview of the role that some new methods are playing in this emerging area of physiological bioenergetics, supported by a few references to our contributions as I scarcely have the faculties now to understand other specific contributions. This new field is brimming with promises for medicine, science and society, in general. I cannot and must not be concrete or comprehensive, because I honestly feel that it is now that matters are really beginning to take off, assisted by the most appropriate international capabilities.

Cite this paper: M. Gosalvez, "Methods to Be Developed for Some First Applications of Mitochondrial Filamentation," Open Journal of Biophysics, Vol. 3 No. 1, 2013, pp. 51-53. doi: 10.4236/ojbiphy.2013.31A006.

[1]   M. Gosalvez, “Mitochondrial Filamentation: Some Methods of Isolation and Assay,” IOSR Journal of Pharmacy and Biological Sciences, Vol. 4, No. 4, 2012, pp. 37-39. doi:10.9790/3008-0443739

[2]   M. Gosalvez, “Metabolic Control of Respiration and Glycolysis of Tumoral Cells,” Advances in Biological Chemistry, 2012, In Press.

[3]   M. Gosalvez, “Cancer as a Therapeutic Agent?” Unpublished.

[4]   M. Gosalvez, “Reversal of Cancer by Dual Strategy,” Unpublished.

[5]   M. Gosalvez, “Mitochondrial Filamentation Future Possibilities Especially in Cancer,” Unpublished.

[6]   M. Gosalvez, “The Great Planetary Oxygen Cycle?” Unpublished.

[7]   M. Gosalvez, “Extension of Metabolic Life?” Unpublished.

[8]   M. Gosalvez, “Cancer Reversal by Dual Strategy,” National Center of Medical Research, Madrid, 1992.

[9]   M. Gosalvez, “Oxygen Production by Filament Mitochondria. Importance in Cancer and Neurodegeneration,” Anales de la Real Nacional Academia de Medicina, Madrid, Vol. 115, No. 3, 1998, pp. 747-756.

[10]   M. Gosalvez, “Reversion of Cancer and Mitochondrial Filamentation,” Anales de la Real Nacional Academia de Medicina, Madrid, Vol. 117, No. 4, 2000, pp. 825-834.

[11]   M. Gosalvez, M. Blanco, P. S. Testillano and M. C. Risueno, “Warm Low Stress Isolated Filamented Mitochondria,” 2nd World Congress of CMB. Cellular and Molecular Biology, Paris, 1996.

[12]   M. Gosalvez and M. Blanco, “Oxygen Production by Filamentous Mitochondria,” Proceedings of the 26th Annual Meeting of ISOTT, Budapest, 23-28 August 1998.

[13]   M. Gosalvez, “Mitochondrial Filamentation,” Proceeding of the AACR 101st Meeting, Washington DC, April, p. 20.

[14]   M. Gosalvez, “Reversal of Cancer by Dual Strategy: A New Molecular Target?” Proceedings of the AACR 103rd Meeting, Chicago, 31 March-4 April 2012, p. 1118.

[15]   J. M. Gobernado, M. Gosalvez, C. Cortina, M. Lousa, C. Riva, A. Gimeno, “Mitochondrial Functions in Chronic Muscular Atrophy,” Journal of Neurology, Neurosurgery & Psychiatry, Vol. 43, No. 6, 1980, pp. 546-549.

[16]   F. O’Connor, J. L. Castillo-Olivares, M. G. Eguaras, A. Juffe, M. Gosalvez and D. Figera, “Anoxic Cardiac Arrest: Its Effect on Myocardial Mitochondrial Metabolism,” The Journal of Cardiovascular Surgery, Vol. 16, No. 5, 1975, pp. 493-499.

[17]   A. Bootello, E. Fernandez-Cruz, P. Escartin, M. F. Blanco, M. Gosalvez and J. M. S. De Arana, “Injurious Effect on Rat Liver Mitochondria by Lymphocytes from Patients with Primary Biliary Cirrhosis,” Clinical & Experimental Immunology, Vol. 24, No. 2, 1976, pp. 374-377.

[18]   J. Diaz Gil, I. Rossi, P. Escartin, J. M. Segovia and M. Gosalvez, “Mitochondrial Functions and Content of Microsomal and Mitochondrial Cytochromes in Human Cirrhosis,” Clinical Science & Molecular Medicine, Vol. 52, No. 6, 1977, pp. 599-606.