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 SS  Vol.4 No.1 , January 2013
Solid-Pseudopapillary Tumor of the Pancreas in Adults: A Case Report
Abstract: Solid-pseudopapillary tumor of the pancreas (SPTP) is an uncommon low grade exocrine pancreatic malignancy. We represented a 22 years old female with an abdominal mass of 4 years history and symptoms of weakness, loss of appetite, 7 kilograms weight loss and swelling for almost 2 months. She was suspected of pancreatic malignancy due her abdominal ultrasound and CT reports and therefore underwent explorative surgery that revealed a huge pancreatic tumor .The tumor was resected totally and hystopathological examination reported significant components of pancreatic solid pseudopapiller tumor features which was also the final diagnosis.
Cite this paper: Gulpinar, K. , Ozdemir, S. , Ozis, E. and Ersoz, S. (2013) Solid-Pseudopapillary Tumor of the Pancreas in Adults: A Case Report. Surgical Science, 4, 77-82. doi: 10.4236/ss.2013.41014.
References

[1]   M. H. Pascual and E. F. Herrero, “Solid-Cystic Papillary Epithelial Neoplasm of the Pancreas. A Diagnostic and Therapeutic Challenge,” Revista Espanola de Enfermedades Digestivas, Vol. 98, No. 11, 2006, pp. 801-808. doi:10.4321/S1130-01082006001100001

[2]   V. K. Frantz, “Tumors of the Pancreas,” Armed Forces Institute of Pathology, Washington DC, 1959, pp. 32-33.

[3]   W. Rebhandl, F. X. Felberbauer, S. Puig, K. Paya, S. Hochschorner, M. Barlan and E. Horcher, “Solid-Pseudopapillary Tumor of the Pancreas (Frantz Tumor) in Children: Report of Four Cases and Review of the Literature,” Journal of Surgical Oncology, Vol. 76, No. 4, 2001, pp. 289-296. doi:10.1002/jso.1048

[4]   K. Y. Lam, C. Y. Lo and S. T. Fan, ‘Pancreatic Solid-Cystic-Papillary Tumor: Clinicopathologic Features in Eight Patients from Hong Kong and Review of the Literature,” World Journal of Surgery, Vol. 23, No. 10, 1999, pp. 1045-1050. doi:10.1007/s002689900621

[5]   T. Papavramidis and S. Papavramidis, “Solid Pseudopapillary Tumors of the Pancreas: Review of 718 Patients Reported in English Literature,” Journal of the American College of Surgeons, Vol. 200, No. 6, 2005, pp. 965-972. doi:10.1016/j.jamcollsurg.2005.02.011

[6]   D. C. Schwartz and M. A. Campos, “A Woman with Recurrent Abdominal Pain,” American Journal of the Medical Sciences, Vol. 321, No. 5, 2001, pp. 352-354. doi:10.1097/00000441-200105000-00009

[7]   D. S. Klimstra, B. M. Wenig and C. S. Heffess, “Solid-Pseudopapillary Tumor of the Pancreas: A Typically Cystic Carcinoma of Low Malignant Potential,” Seminars in Diagnostic Pathology, Vol. 17, No. 1, 2000, pp. 66-80.

[8]   T. Tornoczky, E. Kalman, P. Jakso, G. Mehes, L. Pajor, G. G. Kajtar, I. Battyany, S. Davidovics, M. Sohail and T. Krausz, “Solid and Papillary Epithelial Neoplasm Arising in Heterotopic Pancreatic Tissue of the Mesocolon,” Journal of Clinical Pathology, Vol. 54, No. 3, 2001, pp. 241-245. doi:10.1136/jcp.54.3.241

[9]   G. Balercia, G. Zamboni, G. Bogina and G. M. Mariuzzi, “Solid-Cystic Tumor of the Pancreas. An Extensive Ultrastructural Study of Fourteen Cases,” Journal of Submicroscopic Cytology and Pathology, Vol. 27, No. 3, 1995, pp. 331-340.

[10]   K. Notohara, S. Hamazaki, C. Tsukayama, S. Nakamoto, K. Kawabata, K. Mizobuchi, K. Sakamoto and S. Okada, “Solid-Pseudopapillary Tumor of the Pancreas: Immunohistochemical Localization of Neuroendocrine Markers and CD10,” American Journal of Surgical Pathology, Vol. 24, No. 10, 2000, pp. 1361-1371. doi:10.1097/00000478-200010000-00005

[11]   A. L. Adams, G. P. Siegal and N. C. Jhala, “Solid Pseudopapillary Tumor of the Pancreas: A Review of Salient Clinical and Pathologic Features,” Advances in Anatomic Pathology, Vol. 15, No. 1, 2008, pp. 39-45. doi:10.1097/PAP.0b013e31815e5237

[12]   E. Karagulle, E. Yildirim, E. Turk, H. Kiyici and H. Karakayali, “Solid Pseudopapillary Tumor of the Pancreas: A Case Report,” Turkish Journal of Gastroenterology, Vol. 17, No. 4, 2006, pp. 316-319.

[13]   J. Sakagami, K. Kataoka, Y. Sogame, A. Taii, T. Ojima, D. Kanemitsu, R. Takada, R. Ito, T. Motoyoshi, H. Yasuda, et al., “Solid Pseudopapillary Tumor as a Possible Cause of Acute Pancreatitis,” Journal of the Pancreas, Vol. 5, No. 5, 2004, pp. 348-352.

[14]   H. Omori, H. Asahi, Y. Inoue, T. Irinoda and K. Saito, “Solid and Cystic Tumor of the Pancreas with Massive Hemoperitoneum,” Hepatogastroenterology, Vol. 52, No. 63, 2005, pp. 936-939.

[15]   M. D’Onofrio, R. Malago, F. Vecchiato, G. Zamboni, M. Testoni, M. Falconi, P. Capelli and R. P. Mucelli, “Contrast-Enhanced Ultrasonography of Small Solid Pseudopapillary Tumors of the Pancreas: Enhancement Pattern and Pathologic Correlation of 2 Cases,” Journal of Ultrasound in Medicine, Vol. 24, No. 6, 2005, pp. 849-854.

[16]   F. Miao, Y. Zhan, X. Y. Wang, D. B. Wang, K. M. Chen, A. R. Tang and H. Jiang, “CT Manifestations and Features of Solid Cystic Tumors of the Pancreas,” Hepatobiliary & Pancreatic Diseases International, Vol. 1, No. 3, 2002, pp. 465-468.

[17]   V. Cantisani, K. J. Mortele, A. Levy, J. N. Glickman, P. Ricci, R. Passariello, P. R. Ros and S. G. Silverman, “MR Imaging Features of Solid Pseudopapillary Tumor of the Pancreas in Adult and Pediatric Patients,” American Journal of Roentgenology, Vol. 181, No. 2, 2003, pp. 395-401.

[18]   R. H. Bardales, B. Centeno, J. S. Mallery, R. Lai, M. Pochapin, G. Guiter and M. W. Stanley, “Endoscopic Ultrasound-Guided Fine-Needle Aspiration Cytology Diagnosis of Solid-Pseudopapillary Tumor of the Pancreas: A Rare Neoplasm of Elusive Origin but Characteristic Cytomorphologic Features,” American Journal of Clinical Pathology, Vol. 121, No. 5, 2004, pp. 654-662. doi:10.1309/DKK2B9V4N0W26A8Q

[19]   A. Raffel, K. Cupisti, M. Krausch, S. Braunstein, B. Trobs, P. E. Goretzki and U. Willnow, “Therapeutic Strategy of Papillary Cystic and Solid Neoplasm (PCSN): A Rare Non-Endocrine Tumor of the Pancreas in Children,” Surgical Oncology, Vol. 13, No. 1, 2004, pp. 1-6. doi:10.1016/j.suronc.2003.09.003

[20]   C. Sperti, M. Berselli, C. Pasquali, D. Pastorelli and S. Pedrazzoli, “Aggressive Behaviour of Solid-Pseudopapillary Tumor of the Pancreas in Adults: A Case Report and Review of the Literature,” World Journal of Gastroenterology, Vol. 14, No. 6, 2008, pp. 960-965. doi:10.3748/wjg.14.960

[21]   I. Hassan, I. Celik, C. Nies, A. Zielke, B. Gerdes, R. Moll, A. Ramaswamy, H. J. Wagner and D. K. Bartsch, “Successful Treatment of Solid-Pseudopapillary Tumor of the Pancreas with Multiple Liver Metastases,” Pancreatology, Vol. 5, No. 2-3, 2005, pp. 289-294. doi:10.1159/000085285

[22]   R. Salvia, C. Bassi, L. Festa, M. Falconi, S. Crippa, G. Butturini, A. Brighenti, P. Capelli and P. Pederzoli, “Clinical and Biological Behavior of Pancreatic Solid Pseudopapillary Tumors: Report on 31 Consecutive Patients,” Journal of Surgical Oncology, Vol. 95, No. 4, 2007, pp. 304-310. doi:10.1002/jso.20685

[23]   A. K. Madan, C. B. Weldon, W. P. Long, D. Johnson and A. Raafat, “Solid and Papillary Epithelial Neoplasm of the Pancreas,” Journal of Surgical Oncology, Vol. 85, No. 4, 2004, pp. 193-198. doi:10.1002/jso.20019

[24]   S. Q. Chen, S. Q. Zou, Q. B. Dai and H. Li, “Clinical Analysis of Solid-Pseudopapillary Tumor of the Pancreas: Report of 15 Cases,” Hepatobiliary & Pancreatic Diseases International, Vol. 7, No. 2, 2008, pp. 196-200.

[25]   C. A. Pellegrini, C. F. Heck, S. Raper and L. W. Way, “An Analysis of the Reduced Morbidity and Mortality Rates after Pancreaticoduodenectomy,” Archives of Surgery, Vol. 124, No. 7, 1989, pp. 778-781. doi:10.1001/archsurg.1989.01410070028006

[26]   D. T. Alexandrescu, K. O’Boyle, A. Feliz, A. Fueg and P. H. Wiernik, “Metastatic Solid-Pseudopapillary Tumour of the Pancreas: Clinico-Biological Correlates and Management,” Clinical Oncology, Vol. 17, No. 5, 2005, pp. 358-363. doi:10.1016/j.clon.2004.11.015

[27]   S. M. de Castro, D. Singhal, D. C. Aronson, O. R. Busch, T. M. van Gulik, H. Obertop and D. J. Gouma, “Management of Solid-Pseudopapillary Neoplasms of the Pancreas: A Comparison with Standard Pancreatic Neoplasms,” World Journal of Surgery, Vol. 31, No. 5, 2007, pp. 1130-1135. doi:10.1007/s00268-006-0214-2

[28]   S. Nagri, A. Abdu, S. Anand, M. Krishnaiah and V. Arya, “Liver Metastasis Four Years after Whipple’s Resection for Solid-Pseudopapillary Tumor of the Pancreas,” Journal of the Pancreas, Vol. 8, No. 2, 2007, pp. 223-227.

[29]   C. Mao, M. Guvendi, D. R. Domenico, K. Kim, N. R. Thomford and J. M. Howard, “Papillary Cystic and Solid Tumors of the Pancreas: A Pancreatic Embryonic Tumor? Studies of Three Cases and Cumulative Review of the World’s Literature,” Surgery, Vol. 118, No. 5, 1995, pp. 821-828. doi:10.1016/S0039-6060(05)80271-5

[30]   A. Saiura, N. Umekita, Y. Matsui, T. Maeshiro, S. Miyamoto, M. Kitamura and A. Wakikawa, “Successful Surgical Resection of Solid Cystic Tumor of the Pancreas with Multiple Liver Metastases and a Tumor Thrombus in the Portal Vein,” Hepatogastroenterology, Vol. 47, No. 33, 2000, pp. 887-889.

[31]   L. H. Tang, H. Aydin, M. F. Brennan and D. S. Klimstra, “Clinically Aggressive Solid Pseudopapillary Tumors of the Pancreas: A Report of Two Cases with Components of Undifferentiated Carcinoma and a Comparative Clinicopathologic Analysis of 34 Conventional Cases,” American Journal of Surgical Pathology, Vol. 29, No. 4, 2005, pp. 512-519. doi:10.1097/01.pas.0000155159.28530.88

[32]   A. Maffuz, T. B. Fde, J. A. Silva and S. Torres-Vargas, “Preoperative Gemcitabine for Unresectable, Solid Pseudopapillary Tumour of the Pancreas,” Lancet Oncology, Vol. 6, No. 3, 2005, pp. 185-186. doi:10.1016/S1470-2045(05)01770-5

[33]   C. M. Kang, K. S. Kim, J. S. Choi, H. Kim, W. J. Lee and B. R. Kim, “Solid Pseudopapillary Tumor of the Pancreas Suggesting Malignant Potential,” Pancreas, Vol. 32, No. 3, 2006, pp. 276-280. doi:10.1097/01.mpa.0000202956.41106.8a

 
 
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