Objective: This research compares the nature of 11 kinds of Chinese herbs in the caine kidney mixture, and provides a theoretical way to concentrated prescriptions. Methods: Based on the principal component analysis of element contents in Chinese herbs, the effects of 25 chemical elements in the 11 kinds of Chinese herbs in the caine kidney mixture have been analyzed. Results: The traditional Chinese medicines of rehmannia, astragalus, mulberry, salvia miltiorrhiza, rhubarb in the caine kidney mixture play a major role in the treatment of chronic renal failure. Conclusion: The principal component analysis is very practical in the compatibility of medicines and concentrated prescriptions.
 Jinghuan Guan, Enkuan Li, Xingxin Dai, Sha Xue, Baolin Jian, Xuejun Tang, et al. Quan- tification of traditional Chinese medicine theory and trace elements [M].Wuhan: Hubei Science and Technology Press,1998.
 Yi Liu，Sha Xue，Li Ma,Wei Ma,Wenli Wu. The study on influence of the caine kidney mixture to calcium and phosphorus in blood and urine of chronic renal failure rats induced by adenine [J].Chinese Medicine with Kidney, 2000,1(4):203-205