ENG  Vol.4 No.10 , October 2012
Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles
Abstract: Inclusion of L-DOPA, the standard Parkinson’s disease medication, into polymeric particles (PLGA) results in optimization the drug metabolism and increasing its bioavailability, significantly increases of physical endurance, better coordination and lower anxiety in Wistar rats, when chronically administered nasally.
Cite this paper: I. Kondrasheva, T. Antipova, G. Barsegyan, P. Gambaryan, A. Guseva and A. Kamensky, "Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles," Engineering, Vol. 4 No. 10, 2012, pp. 27-29. doi: 10.4236/eng.2012.410B007.

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