Saurabh Agarwal, Mohan Jagade, Aseem Mishra, Shreyas Joshi

Show more
Depatment of Ear, Nose and Throat & Head & Neck Surgery, Grant Medical College, Mumbai, India.
Show less

Abstract: Myoepithelioma is a rare neoplasm of the salivary glands, generally occurring in the parotid gland and less often in the minor accessory salivary gland of the oral cavity. The histological appearance includes solid, myxoid and reticular growth patterns. Vimentin and S-100 protein are very sensitive but non-specific immunohistochemical markers of neoplastic myoepithelium. Conservative surgery is the treatment of choice. A case of myoepithelioma of the minor salivary gland of tongue is described, focusing on clinical behaviour, histopathological and immunohistochemical features.

Keywords: Salivary Gland Tumour; Tongue; Myoepithelioma

Cite this paper: S. Agarwal, M. Jagade, A. Mishra and S. Joshi, "Myoepithelioma of Tongue," International Journal of Otolaryngology and Head & Neck Surgery, Vol. 2 No. 1, 2013, pp. 8-10. doi: 10.4236/ijohns.2013.21003.

References

[1]   F. Martinez-Madrigal and C. Micheau, “Histology of the Major Salivary Glands,” The American Journal of Surgical Pathology, Vol. 13, No. 10, 1989, pp. 879-899. doi:10.1097/00000478-198910000-00008

[2]   J. J. Sciubba and R. B. Brannon, “Myoepithelioma of Salivary Glands: Report of 23 Cases,” Cancer, Vol. 49, No. 3, 1982, pp. 52-72. doi:10.1002/1097-0142(19820201)49:3<562::AID-CNCR2820490328>3.0.CO;2-6

[3]   J. G. Batsakis, “Myoepithelioma,” The Annals of Otology, Rhinology, and Laryngology, Vol. 94, No. 5, 1985, pp. 523-524.

[4]   G. Seifert, “World Health Organization International Histological Classification of Tumours,” Histological Typing of Salivary Gland Tumours, 2nd Edition, Heidelberg, Berlin, 1991.

[5]   E. Katsuyama, A. Kaneoka and K. Higuchi, “Myoepithelioma of the Soft Palate,” Acta Cytologica, Vol. 41, 1997, pp. 1856-1886.

[6]   A. Piattelli, M. Fioroni and C. Rubini, “Myoepithelioma of Gengiva. Report of a Case,” Journal of Periodontology, Vol. 70, No. 6, 1999, pp. 683-687. doi:10.1902/jop.1999.70.6.683

[7]   R. H. W. Simpson, H. Jones and P. Beasley, “Benign Myoepithelioma of the Salivary Glands: A True Entity?” Histopathology, Vol. 27, No. 1, 1995, pp. 1-9. doi:10.1111/j.1365-2559.1995.tb00284.x

[8]   G. L. Ellis and P. L. Auclair, “Tumours of the Salivary Glands,” Armed Forces Institute of Pathology, Washington DC, 1996.

[9]   J. G. Batsakis, B. Kraemer and J. J. Sciubba, “The Pathology of Head and Neck Tumours: The Myoepithelial Cell and Its Participation in Salivary Gland Neoplasia, Part 17,” Head and Neck Surgery, Vol. 5, No. 3, 1983, pp. 222-233. doi:10.1002/hed.2890050307

[10]   I. Dardick and A. W. Van Nostrand, “Myoepithelial Cells in Salivary Gland Tumour,” Head and Neck Surgery, Vol. 7, No. 5, 1985, pp. 395-408. doi:10.1002/hed.2890070509

[11]   R. L. Corio, J. J. Sciubba and R. B. Brannon, “Epithelial-Myoepithelial Carcinoma of Intercalated Duct Origin,” Oral Surgery, Vol. 53, No. 3, 1982, pp. 280-287. doi:10.1016/0030-4220(82)90304-8

[12]   S. H. Thompson, S. Bender and A. Richards, “Plasmacytoid Myoepithelioma of a Minor Salivary Glands,” Journal of Oral and Maxillofacial Surgery, Vol. 43, No. 4, 1985, pp. 285-288. doi:10.1016/0278-2391(85)90289-7

[13]   J. Taylor and J. V. Tighe, “A Minor Salivar Gland Tumour Presenting with Dysphagia,” The Journal of Laryngology & Otology, Vol. 113, No. 8, 1999, pp. 569-572. doi:10.1017/S0022215100144512

[14]   I. Dardick, M. J. Thomas and A. W. Van Nostrand, “Myoepithelioma—New Concepts of Histology and Classification: A Light and Electron Microscopic Study,” Ultrastructural Pathology, Vol. 13, No. 2-3, 1989, pp. 187-224. doi:10.3109/01913128909057442

[15]   I. Dardick, “Myoepitheliomas: Definitions and Diagnostic Criteria,” Ultrastructural Pathology, Vol. 19, No. 5, 1995, pp. 359-369. doi:10.3109/01913129509021906

[16]   A. K. El-Naggar, M. Lovell, D. L. Callender, N. G. Ordonez and A. M. Killary, “Cytogenetic Analysis of a Primary Salivary Gland Myoepithelioma,” Cancer Genetics and Cytogenetics, Vol. 113, No. 1, 1999, pp. 49-53. doi:10.1016/S0165-4608(98)00280-5

[17]   L. Alos, A. Cardesa, J. A. Bombi, C. Mallofre, A. Cuchi and J. Traserra, “Myoepithelial Tumours of Salivary glands: A Clinicopathologic, Immunohistochemical, Ultrastructural and Flow-Cytometric Study,” Seminars in Diagnostic Pathology, Vol. 13, No. 2, 1996, pp. 138-147.

[18]   M. J. Merino and V. A. LiVolsi, “Pleomorphic Adenomas of the Parotid Gland Resembling Mesenchymal Tumours,” Oral Surgery, Vol. 44, No. 3, 1977, pp. 405-410. doi:10.1016/0030-4220(77)90410-8

[19]   I. Dardick and A. P. W. Van Nostrand, “Polymorphus Low-Grade Adenocarcinoma: A Case Report with Ultrastructural Findings,” Oral Surgery, Oral Medicine, Oral Pathology, Vol. 66, No. 4, 1988, pp. 459-465. doi:10.1016/0030-4220(88)90269-1

[20]   T. Nagao, I. Sugano and Y. Ishida, “Salivary Gland Malignant Myoepithelioma. A Clinicopathologic and Immunohistochemical Study of Ten Cases,” Cancer, Vol. 83, No. 7, 1988, pp. 1292-1299. doi:10.1002/(SICI)1097-0142(19981001)83:7<1292::AID-CNCR4>3.0.CO;2-L