ABSTRACT The effect of L-cysteine of argentum nitrate gel on the wound process of experimental animals is investigated. The results show that the nanogel, being bacteriostatic, accelerates the course of inflammation phase resulting in fast cleansing of the wound surface and stimulation of the granulation tissue formation. The main cell elements of this tissue—fibroplasts are characterized by the state of functional excitation. The time of wound healing with the use of L-cysteine of argentum nitrate gel was reduced by three days, and the index of wound repair acceleration was about 20%.
Cite this paper
Petrova, M., Pavlova, N., Kharitonova, E. and Ilyashenko, N. (2012) Reparative histogenesis of skin: Reaction on the application of l-cysteine of argentum nitrate gel. Open Journal of Regenerative Medicine, 1, 25-28. doi: 10.4236/ojrm.2012.13004.
 Abayev, Y.K. (2006) Surgeon reference book. Wounds and wound infection. Medicine, Moskow.
 Mehendale, F. and Martin, P. (2001) The cellular and molecular events of wound healing. Martin Dunitz, London.
 Nozdrin, V.I. (2006) Hystopharmacologic studies of skin. Retinoidy, Moskow.
 Efimenko, N.A., et al. (2002) Current Trends in produc- ing of biologically active materials for healing of fester- ing wounds. Voenno-Medicinsky Zhurnal, 1, 48-52.
 Petrova, M.B., Pustovalova R.A., Kharitonova E.A., Pavlova N.V. (2012) Reparative process in skin. Palmar- ium Academic Publishing GmbH& Co., Saarbrücken.
 Petrova, M.B., Shestakova, V.G., Kharitonova, E.A., Pav- lova, N.V. and Kurbatova, L.A. (2012) Evaluation of acu- puncture effect in skin wound healing with helping of the electronic microscope. Proceedings of the International Conference Theoretical and Practice Innovation in Science, Gdańsk, 28-30 April 2012, 14-18.
 Tavacalyan, N.B. and Oganesyan, A.N. (2007) Anti-burn materials on the basis of vinyl acetate polymers. Proceed- ings of the International Conference New Polimers and Radioprotectors for Biology and Medicine, Yerevan, 8-10 October 2007, 186-188.
 Ilyin, S., et al. (2011) Gels of cysteine/Ag-based dilute colloid systems and their rheological properties. Soft Matter, 7, 9090-9103. doi:10.1039/c1sm06007d
 Chervinets, V.M., Bondarenko, V.M., Chervinets, Y.V., Ovchinnikov, M.M., Samoukina, A.M., Mikhaylova, E.S., Petrova, M.B., Kharitonova, E.A. and Bryantseva, V.M. (2011) Antibacterial activity of nanostructured silver gel. Journal of Microbiology Epidemiology and Immunobiol- ogy, 4, 88-92.
 Danilov, R.K. (2008) Wounding process: Histogenetic base. Voenno-Medicinsky vestnik, Snt-Petersburg.
 Baum, C.L. and Arpey, C. (2005) Normal cutaneous wound healing: Clinical correlation with cellular and mo- lecular events. Dermatologic Surgery, 31, 674-686.
 Desmouliere, A. (2005) Tissue repair, contraction and the myofibroblast. Wound Repair and Regeneration, 13, 7- 12.
 Locono, J.A. (1998) The biology of healing. In Locono J.A., Leaper, D.J. and Harding K.G., Eds., Wounds: Biol- ogy and Management, Oxford University Press, Oxford New York, 10-22.
 Mast, B.A. (1992) Wound healing: Biochemical and cli- nical aspects: Monography. W. B. Saunders Company, London.