OJST  Vol.2 No.4 , December 2012
The effect of green tea mouthwash (Camellia sinensis) on wound healing following periodontal crown lengthening surgery; a double blind randomized controlled trial
Green tea has been used as a traditional medicine since 2700 BC and several studies have shown that green tea polyphenols inhibit the growth of oral and periodontal pathogenic bacteria and can improve oral and gingival health. In this clinical study we investigated the effect of green tea mouthwash on microbial dental plaque and gingival inflammation following periodontal surgery. A total of 34 crown lengthening surgeries were included in this study. After removing periodontal dressing, green tea mouthwash for the test group and placebo for the patients in the control group were prescribed, and periodontal parameters were assessed at base line and after 2 weeks. Analysis of the data revealed the significant effect of green tea mouthwash on reducing Plaque index (PI), Gingival Index (GI) and Bleeding on probing (BOP). Therefore it would be recommended as a safe, anti-inflammatory and anti-microbial mouthwash for treating gingival inflammation and maintaining oral and gingival health.

Cite this paper
Forouzanfar, A. , Arab, H. , Shafaee, H. , Mokhtari, M. and Golestani, S. (2012) The effect of green tea mouthwash (Camellia sinensis) on wound healing following periodontal crown lengthening surgery; a double blind randomized controlled trial. Open Journal of Stomatology, 2, 369-372. doi: 10.4236/ojst.2012.24064.
[1]   Liao, S., Kao, Y.H. and Hiipakka, R.A. (2001) Green tea: Biochemical and biological basis for health benefits. Vitamins and Hormones, 62, 1-94. doi:10.1016/S0083-6729(01)62001-6

[2]   Arab, H., Maroofian, A., Golestani, S., Shafaee, H., Sohrabi, K. and Forouzanfar, A. (2011) Review of The therapeutic effects of Camellia sinensis (green tea) on oral and periodontal health. Journal of Medicinal Plants Research, 5, 5465-5469.

[3]   Newman, M.G., Takei, H.H., Klokkevold, P. and Carranza, F.A. (2006) Carranza’s Clinical Periodontology, 71, 1039-1049.

[4]   Hull, P.S. (1980). Chemical inhibition of plaque. Journal of Clinical Periodontology, 7, 431-442. doi:10.1111/j.1600-051X.1980.tb02150.x

[5]   Addy, M. (1986) Chlorhexidine compared with other locally delivered anti-microbials. A short review. Journal of Clinical Periodontology, 13, 957-964. doi:10.1111/j.1600-051X.1986.tb01434.x

[6]   Kornman, K.S. (1986) Anti-microbial agents. In: Lee, H. and Kleinman, D.V., Eds, Dental Plaque Control Measures and Oral Hygiene Practices, IRL Press, Oxford, pp. 121-142.

[7]   Mandel, I.D. (1988) Chemotherapeutic agents for controlling plaque and gingivitis. Journal of Clinical Periodontology, 15, 488-496. doi:10.1111/j.1600-051X.1988.tb01020.x

[8]   Gjermo, P. (1989) Chlorhexidine and related compounds. Journal of Dental Research, 68, 1602-1608.

[9]   Addy, M., Moran, J. and Wade, W. (1994) Chemical plaque control in the prevention of gingivitis and periodontitis. In: Lang, N.E. and Karring, T., Eds., Proceedings of the 71st European Workshop on Periodontology, Quintessence Publishing, London, pp. 244-257.

[10]   Heasman, P.A. and Seymour, RA. (1994) Pharmacological control of periodontal disease. 1. Anti-plaque agents. Journal of Dentistry, 22, 323-326. doi:10.1016/0300-5712(94)90083-3

[11]   Jackson, R.J. (1997) Metal salts, essential oils and phenols-old or new? In: Addy, M. and Moran, J.M., Eds., Toothpaste, Mouth Rinse and Other Topical Remedies in Periodontics, Periodontology, 15, 63-73.

[12]   Tariq, M., Naveed, A. and Barkat Ali, K. (2010) The morphology, characteristics, and medicinal properties of Camellia sinensis’ tea. Journal of Medicinal Plants Research, 4, 2028-2033.

[13]   Cabrera, C., Giménez, R. and López, M.C. (2003) Determination of tea components with antioxidant activity. Journal of Agricultural and food chemistry, 51, 4427- 4435. doi:10.1021/jf0300801

[14]   Cabrera, C., Artacho, R. and Giménez, R. (2006) Beneficial effects of green tea―A review. Journal of American College of Nutrition, 25, 79-99.

[15]   Makimura, M., Hirasawa, M. and Kobayashi, K. (1993) Inhibitory effect of tea catechins on collagenase activity. Journal of Periodontology, 64, 630-636. doi:10.1902/jop.1993.64.7.630

[16]   Magnusson, I., Lindhe, J., Yoneyama, T. and Liljenberg, B. (1984) Recolonization of a subgingival microbiota following scaling in deep pockets. Journal of Clinical Periodontology, 11, 193-207. doi:10.1111/j.1600-051X.1984.tb01323.x

[17]   Sakanaka, S. and Okada, Y. (2004) Inhibitory effects of green tea polyphenols on the production of a virulence factor of the periodontal disease-causing anaerobic bacterium Porphyromonas gingivalis. Journal of Agricultural and Food Chemistry, 52, 1688-1692. doi:10.1021/jf0302815

[18]   Hirasawa, M., Takada, K., Makimura, M. and Otake, S. (2002). Improvement of periodontal status by green tea catechin using a local delivery system: A clinical pilot study. Journal of Periodontal Research, 37, 433-438. doi:10.1034/j.1600-0765.2002.01640.x

[19]   Kushiyama, M., Yoshihiro, S., Masatoshi, M. and Yoshihisa, Y. (2009) Relationship between intake of green tea and periodontal disease. Journal of Periodontology, 80, 372-377. doi:10.1902/jop.2009.080510

[20]   Bors, W., Heller, W., Michel, C. and Saran, M. (1990) Flavonoids as antioxidants: Determination of radical-scavenging efficiencies. Methods in Enzymology, 186, 343-355. doi:10.1016/0076-6879(90)86128-I

[21]   Rizvi, S.I., Zaid, M.A., Anis, R. and Mishra, N. (2005) Protective role of tea catechins against oxidation-induced damage of type 2 diabetic erythrocytes. Clinical and Experimental Pharmacology and Physiology, 32, 70-75. doi:10.1111/j.1440-1681.2005.04160.x