JCDSA  Vol.2 No.4 , December 2012
Reed Nevus (Pigmented Spindle Cell Nevus) in an 11-Month-Old Japanese Infant
Reed nevus (pigmented spindle cell nevus) is a nevus with the histopathological features of abundant melanin, monomorphic spindle-epithelioid melanocytes, spindle cell nests confined within the epidermis and papillary dermis, and occasional upward interepidermal progression of melanocytes. Here, we reported an unusual case of Reed nevus in an 11-month-old Japanese male infant. Infantile Reed nevus should be included as a differential diagnosis for nevus pigmentosus in infancy.

Cite this paper
M. Fujita, N. Oiso and A. Kawada, "Reed Nevus (Pigmented Spindle Cell Nevus) in an 11-Month-Old Japanese Infant," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 2 No. 4, 2012, pp. 239-240. doi: 10.4236/jcdsa.2012.24045.

[1]   K. K. Boneti, J. Pineiro-Maceira, F. B. Pereira and C. B. Barcaui, “Reed Nevus (Pigmented Spindle-Cell Nevus): A Report of Three Cases with Distinct Dermoscopic Patterns,” Anais Brasileiros de Dermatologia, Vol. 85, No. 4, 2010, pp. 531-536. doi:10.1590/S0365-05962010000400016

[2]   G. Ferrara, G. Argenziano, H. P. Soyer, S. Chimenti, A. Di Blasi, G. Pellacani, K. Peris, D. Piccolo, P. Rubegni, S. Seidenari, S. Staibano, I. Zalaudek and G. De Rosa, “The Spectrum of Spitz Nevi: A Clinicopathologic Study of 83 Cases,” Archive of Dermatology, Vol. 141, No. 11, 2005, pp. 1381-1387. doi:10.1001/archderm.141.11.1381

[3]   S. A. Webber, G. Siller and H. P. Soyer, “Pigmented Spindle Cell Naevus of Reed: A Controversial Diagnostic Entity in Australia,” Australian Journal of Dermatology, Vol. 52, No. 11, 2011, pp. 104-108. doi:10.1111/j.1440-0960.2011.00743.x

[4]   R. L. Barnhill, M. A. Barnhill, M. Berwick and M. C. Mihm Jr., “The Histologic Spectrum of Pigmented Spindle Cell Nevus: A Review of 120 Cases with Emphasis on Atypical Variants,” Human Pathology, Vol. 22, No. 1, 1991, pp. 52-58. doi:10.1016/0046-8177(91)90061-S

[5]   P. Sau, J. H. Graham and E. B. Helwig, “Pigmented Spindle Cell Nevus: A Clinicopathologic Analysis of Ninety-Five Cases,” Journal of American Academy of Dermatology, Vol. 28, No. 4, 1993, pp. 565-571. doi:10.1016/0190-9622(93)70075-5

[6]   V. Martin, S. Banfi, A. Bordoni, S. Leoni-Parvex and L. Mazzucchelli, “Presence of Cytogenetic Abnormalities in Spitz Naevi: A Diagnostic Challenge for Fluorescence in Situ Hybridization Analysis,” Histopathology, Vol. 60, No. 2, 2012, pp. 336-346. doi:10.1111/j.1365-2559.2011.04087.x

[7]   B. C. Bastian, U. Wesselmann, D. Pinkel and P. E. Leboit, “Molecular Cytogenetic Analysis of Spitz Nevi Shows Clear Differences to Melanoma,” Journal of Investigative Dermatology, Vol. 113, No. 6, 1999, pp. 1065-1069. doi:10.1046/j.1523-1747.1999.00787.x

[8]   N. Oiso, Y. Tatsumi, T. Arao, S. Rai, M. Kimura, S. Nakamura, T. Itoh, K. Nishio, I. Matsumura and A. Kawada, “Loss of Genomic DNA Copy Numbers in the p18, p16, p27 and RB Loci in Blastic Plasmacytoid Dendritic Cell Neoplasm,” European Journal of Dermatology, Vol. 22, No. 3, 2012, pp. 393-394.