IJOHNS  Vol.1 No.3 , November 2012
Angiosarcoma of Maxillary Sinus: A Case Report
Abstract: Purpose: To describe a rare malignancy involving the sinonasal cavities. To discuss the clinical, diagnostic, and treatment modalities. Study Design: A case report including histopathological, radiological analysis and review of literature. Method: A case report is described from a tertiary care centre. Histopathological and radiological details are reviewed. Results: This case report presents a 29 year old male with 3 days history of bleeding from the left nostril, blood stained saliva with post nasal discharge and head ache. Biopsy demonstrated poorly differentiated Angiosarcoma. On immune stains the tumor cells showed diffuse strong cytoplasmic membrane positivity with CD 31 and few cells are positive for CD34. FLI-1 is also positive. Conclusion: Angiosarcoma is a rare malignancy involving the sinonasal cavities. Multidisciplinary approach is essential to obtain clear diagnoses and appropriate treatment plans.
Cite this paper: nullD. Deenadayal, B. Kumar and B. Kumar, "Angiosarcoma of Maxillary Sinus: A Case Report," International Journal of Otolaryngology and Head & Neck Surgery, Vol. 1 No. 3, 2012, pp. 85-87. doi: 10.4236/ijohns.2012.13017.

[1]   N. Zachariades and P. Economopoulou, “Maxillary Angiosarcoma,” International Journal of Oral and Maxillofacial Surgery, Vol. 15, No. 3, 1986, pp. 357-360. Hdoi:10.1016/S0300-9785(86)80101-6

[2]   M. Bankaci, E. N. Myers, L. Barnes, et al., “Angiosarcoma of the Maxillary Sinus,” Head & Neck Surgery, Vol. 1, No. 3, 1979, pp. 274-280. Hdoi:10.1002/hed.2890010311

[3]   D. M. F. Christopher, “Diagnostic Histopathology of Tumors,” Elsevier Health Sciences Imprint, Churchill Livingstone, Vol. 1, 2007, p. 131.

[4]   M. Kurien, S. Nair and S. Thomas, “Angiosarcoma of the Nasal Cavity and Maxillary Antrum,” Journal of Laryngology & Otology, Vol. 103, No. 9, 1989, pp. 874-876. Hdoi:10.1017/S0022215100110369

[5]   Y. Kimura, S. Tanaka and M. Furukawa, “Angiosarcoma of the Nasal Cavity,” Journal of Laryngology & Otology, Vol. 106, No. 4, 1992, pp. 368-369. Hdoi:10.1017/S0022215100119528

[6]   B. L. Nelson and L. D. R. Thompson, “Sinonasal Tract Angiosarcoma: A Clinicopathologic and Immunophenotypic Study of 10 Cases with a Review of the Literature,” Head and Neck Pathology, Vol. 1, No. 1, 2007, pp. 1-12. Hdoi:10.1007/s12105-007-0017-2