ABSTRACT Pilomatrix Carcinoma (PC) is an exceedingly rare neoplasm. Although it has been described at various anatomical sites, fewer than 25 cases have been reported in the face and scalp. Although early recognition and treatment is paramount in optimization of outcomes for this aggressive carcinoma, the diagnosis is complicated by shared features with its more common benign counterpart. In patients with recurrence or rapid growth of a pilomatrixoma, pilomatrix carcinoma should be considered in the differential diagnosis.
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nullV. Duarte, A. Sepahdari, P. Abasolo and M. John, "Pilomatrix Carcinoma of the Head and Neck: Case Report and Review of the Literature," International Journal of Otolaryngology and Head & Neck Surgery, Vol. 1 No. 3, 2012, pp. 53-56. doi: 10.4236/ijohns.2012.13012.
 N. G. Mikhaeel and M. F. Spittle, “Malignant Pilomatrixoma with Multiple Local Recurrences and Distant Metastases: A Case Report and Review of Literature,” Clinical Oncology, Vol. 13, 2001, pp. 386-389.
 D. Hardisson, M. D. Linares, J. Cuevas-Santos and F. Contreras, “Pilomatrix Carcinoma: A Clinicopathologic Study of Six Cases and Review of the Literature,”. The American Journal of Dermatopathology, Vol. 23, No. 5, 2001, pp. 394-401.
 M. Nishioka, A. Tanemura, T. Yamanaka, et al., “Pilomatrix Carcinoma Arising from Pilomatricoma after 10-year Senescent Period: Immunohistochemical Analysis,” Journal of Dermatology, Vol. 37, No. 8, 2010, pp. 735-739. doi:10.1111/j.1346-8138.2010.00887.x
 J. Sassmannshausen and M. Chaffins, “Pilomatrix Carcinoma: A Report of a Case Arising from a Previously Excised Pilomatrixoma and Review of the Literature,” Journal of the American Academy of Dermatology, Vol. 44, No. 2, 2001, pp. 358-361.
 P. Vico, I. Rahier, G. Ghanem, P. Nagypal and R. Deraemaecker, “Pilomatrix Carcinoma,” European Journal of Surgical Oncology, Vol. 23, No. 4, 1997, pp. 370-371.
 L. Autelitano, F. Biglioli and G. Colletti, “Pilomatrix Carcinoma with Visceral Metastases: Case Report and Review of the Literature,” Journal of Plastic, Reconstructive, and Aesthetic Surgery, Vol. 62, No. 12, 2009, pp. 574-577. doi:10.1016/j.bjps.2008.08.024
 S. Lopansri and M. Mihm, “Pilomatrixoma Carcinoma or Calcifying Epitheliocarcinoma of Malherbe,” Cancer, Vol. 45, 1980, pp. 2368-2373.
 R. M. Bremnes, J. M. Kvamme, H. Stalsberg and E. A. Jacobsen, “Pilomatrix Carcinoma with Multiple Metastases: Report of a Case and Review of the Literature,” European Journal of Cancer, Vol. 35, No. 3, 1999, pp. 433-437. doi:10.1016/S0959-8049(98)00299-8
 P. Sau, G. P. Lupton and J. Graham, “Pilomatrixoma Carcinoma,” Cancer, Vol. 71, 1993, pp. 2491-2498.
 A. D. Cohen, S. J. Lin, C. A. Hughes, Y. H. An and J. Maddalozzo, “Head and neck Pilomatrixoma in children,” Archives of Otolaryngology—Head & Neck Surgery, Vol. 127, No. 12, 2001, pp. 1481-1483.
 H. P. Niedermeyer, K. Peris and H. Hofler, “Pilomatrix Carcinoma with Multiple Visceral Metastases: Report of a Case,” Cancer, Vol. 77, 1996, pp. 1311-1314.
 D. Monchy, S. McCarthy and D. Dubourdieu, “Malignant Pilomatrixoma of the Scalp,” Pathology, Vol. 27, No. 2, 1995, pp. 201-203. doi:10.1080/00313029500169892