ABSTRACT Purpose: To investigate the efficacy and complications of continuous wear of etafilcon A for therapeutic use. Materials and Methods: The subjects were 228 eyes of 219 outpatients prescribed contact lens (CL) for one week of continuous therapeutic wear during 10 years. The reason for prescription of CLs, the primary disease, the duration of CL wear and the complications were assessed retrospectively. Results: The predominant reason for prescription of CLs was relief of pain or a foreign-body sensation (62.3%) and protection of the corneal epithelium (20.6%). The primary disease was post-penetrating keratoplasty (36.8%), followed by corneal epithelial erosion (14.5%), post-lamellar keratoplasty (14.0%) and bullous keratopathy (12.2%). The average duration of wearing single lens was 6.5 ± 3.2 days. The average duration of wearing CLs in total was 9.2 ± 10.7 months. The most frequent problem associated with continuous wear of CLs was their dropping out of CLs (12.3%). The complications associated with CLs included conjunctivitis with papillary hyperplasia, corneal erosion and superficial punctate keratitis, but corneal ulcer and corneal infiltrates were not found. Conclusion: Serious complications were not shown changing the lenses every week to keep to the prescribed time limit for continuous therapeutic wear, even if corneal epithelial barrier function is impaired.
Cite this paper
D. Kudo, H. Toshida, T. Ohta and A. Murakami, "Continuous Wear of Hydrogel Contact Lenses for Therapeutic Use," Open Journal of Ophthalmology, Vol. 2 No. 4, 2012, pp. 110-113. doi: 10.4236/ojoph.2012.24023.
 P. Donshik, F. J. Weinstock, S. Wechsler, P. Asbell, J. Atwood, H. Davis, B. Farkas, R. L. Farris, E. Gruber and J. Hartstein, “Disposable Hydrogel Contact Lenses for Extended Wear”, Contact Lens Association of Ophthalmologists Journal, Vol. 14, No. 4, 1988, pp. 191-194.
 J. E. Josephson, B. E. Caffery, I. Campbell and A. R. Slomovic, “Disposable Contact Lenses vs. Contact Lens Maintenance for Extended Wear,” Contact Lens Association of Ophthalmologists Journal, Vol. 16, No. 3, 1990, pp. 184-188.
 K. J. Lindahl, M. D. DePaolis, J. V. Aquavella, G. O. Temnycky and R. A. Erdey, “Applications of Hydrophilic Disposable Contact Lenses as Therapeutic Bandages,” Contact Lens Association of Ophthalmologists Journal, Vol. 17, No. 4, 1991, pp. 241-243.
 E. Gruber, “The Acuvue Disposable Contact Lens as a Therapeutic Bandage Lens,” Annals of Ophthalmology, Vol. 23, No. 12, 1991, pp. 446-447.
 C. S. Bouchard and S. N. Trimble, “Indications and Complications of Therapeutic Disposable Acuvue Contact Lenses”, Contact Lens Association of Ophthalmologists Journal, Vol. 22, No. 2, 1996, pp. 106-108.
 M. Srur and D. Dattas, “The Use of Disposable Contact Lenses as Therapeutic Lenses,” Contact Lens Association of Ophthalmologists Journal, Vol. 23, No. 1, 1997, pp. 40-42.
 L. Lim, D. T. Tan and W. K. Chan, “Therapeutic Use of Bausch & Lomb Pure Vision Contact Lenses”, Contact Lens Association of Ophthalmologists Journal, Vol. 27, No. 4, 2001, pp. 179-185.
 J. Montero, J. Sparholt and R. Mély, “Retrospective Case Series of Therapeutic Applications of a Lotrafilcon a Silicone Hydrogel Soft Contact Lens,” Eye & Contact Lens, Vol. 29, No. 1, 2003, pp. S54-S56.
 J. P. Szaflik, A. M. Ambroziak and J. Szaflik “Therapeutic Use of a Lotrafilcon a Silicone Hydrogel Soft Contact Lens as a Bandage after LASEK Surgery,” Eye & Contact Lens, Vol. 30, No. 1, 2004, pp. 59-62.
 A. M. Ambroziak, J. P. Szaflik and J. Szaflik, “Therapeutic Use of a Silicone Hydrogel Contact Lens in Selected Clinical Cases,” Eye & Contact Lens, Vol. 30, No. 1, 2004, pp. 63-67.
 R. Arora, S. Jain, S. Monga, R. Narayanan, U. K. Raina and D. K. Mehta, “Efficacy of Continuous Wear Pure Vision Contact Lenses for Therapeutic Use,” Contact Lens & Anterior Eye, Vol. 27, No. 1, 2004, pp. 39-43.
 C. C. Karlgard, L. W. Jones and C. Moresoli, “Survey of Bandage Lens Use in North America, October-December 2002,” Eye & Contact Lens, Vol. 30, No. 1, 2004, pp. 25- 30. doi:10.1097/01.ICL.0000105564.71700.EE
 Y. Ozkurt, O. Rodop, Y. Oral, A. Comez, B. Kandemir and O. K. Dogan, “Therapeutic Applications of Lotrafilcon a Silicone Hydrogel Soft Contact Lenses,” Eye & Contact Lens, Vol. 31, No. 6, 2005, pp. 268-269.
 J. R. Armstrong, K. L. Cohen and L. R. McCarthy, “Haemophilus Influenzae Corneal Ulcer in a Therapeutic Contact Lens Wearer,” British Journal of Ophthalmology, Vol. 68, No. 3, 1984, pp. 188-191.
 S. Koh, N. Maeda, T. Soma, Y. Hori, M. Tsujikawa, H. Watanabe and K. Nishida, “Development of Methicillin-Resistant Staphylococcus Aureus Keratitis in a Dry Eye Patient with a Therapeutic Contact Lens,” Eye & Contact Lens, Vol. 38, No. 3, 2012, pp. 200-202.
 N. Inoue, H. Toshida, N. Mamada, N. Kogure and A. Murakami, “Contact Lens-Induced Infectious Keratitis in Japan,” Eye & Contact Lens, Vol. 33, No. 2, 2007, pp. 65-69. doi:10.1097/01.icl.0000233869.21964.1b
 L. B. Szczotka-Flynn, S. Bajaksouzian, M. R. Jacobs, and A. Rimm, “Risk Factors for Contact Lens Bacterial Contamination during Continuous Wear,” Optometry & Vision Science, Vol. 86, No. 11, 2009, pp. 1216-1226.
 F. R. Edmunds, L. C. Timothy and W. T. Reindel, “Cumulative Clinical Results and Projected Incident Rates of Microbial Keratitis with Pure-Vision Silicone-Hydrogel Lenses,” International Contact Lens Clinic, Vol. 27, No. 5, 2000, pp. 182-186.
 T. Sakimoto, Y. Miyamoto, M. Fukuda, Y. Shimomura, K. Takahashi, T. Ishikawa, A. Murakami, K. Nakayasu, S. Takeda, Y. Kamei, M. Matsubara, T. Sakimoto, N. Takaura, N. Fushimi, M. Sawa and Y. Kashima, “Clinical-Report on Long-Term Extended Wear of Silicone Hydrogel Soft Contact Lens (RD-677),” Japanese Journal of Contact Lens Society, Vol. 47, No. 1, 2005, pp. 6-21.
 F. Stapleton, L. Keay, K. Edwards, T. Naduvilath, J. K. Dart, G. Brian and B. A. Holden, “The Incidence of Contact Lens-Related Microbial Keratitis in Australia”, Ophthalmology, Vol. 115, No. 10, 2008, pp. 1655-1662.