Prevalence of congenital hydrocephalus in the Hashemite kingdom of Jordan: A hospital-based study
Affiliation(s)
Department of Biology, University of Jordan, Amman, Jordan;. Department of Pediatrics, Al Bashir Hospital, Amman, Jordan.
Department of Biology, University of Jordan, Amman, Jordan;. Department of Pediatrics, Al Bashir Hospital, Amman, Jordan.
ABSTRACT
Background: Congenital hydrocephalus, an important cause of neurologic morbidity and mortality in children, is a medical condition characterized by an abnormal accumulation of cerebrospinal fluid in the brain. It can be caused by abnormal brain development, obstruction of the cerebral aqueduct flow, Chiari malformations, and Dandy-Walker malformation. The prevalence of congenital hydrocephalus is 2.2 to 18 per 10,000 live births. Objectives: To determine the prevalence of congenital hydrocephalus among livebirths in the Hashemite Kingdom of Jordan (HKJ). Methods: Clinical data were collected from medical records of all livebirths with congenital hydrocephalus born at Al Bashir Hospital, Amman/The Hashemite Kingdom of Jordan in 2004-2005 and 2008-2011. Descriptive analysis was carried out using the Statistical Package for the Social Science (SPSS 20). Results: The prevalence of hydrocephalus was 0.092% with a relative predominance among males. Conclusion: The study concluded that the prevalence of congenital hydrocephalus is comparable to that of developed countries. The efforts made by the Ministry of Health seem to have paid off. More research on stillbirths is recommended.
Background: Congenital hydrocephalus, an important cause of neurologic morbidity and mortality in children, is a medical condition characterized by an abnormal accumulation of cerebrospinal fluid in the brain. It can be caused by abnormal brain development, obstruction of the cerebral aqueduct flow, Chiari malformations, and Dandy-Walker malformation. The prevalence of congenital hydrocephalus is 2.2 to 18 per 10,000 live births. Objectives: To determine the prevalence of congenital hydrocephalus among livebirths in the Hashemite Kingdom of Jordan (HKJ). Methods: Clinical data were collected from medical records of all livebirths with congenital hydrocephalus born at Al Bashir Hospital, Amman/The Hashemite Kingdom of Jordan in 2004-2005 and 2008-2011. Descriptive analysis was carried out using the Statistical Package for the Social Science (SPSS 20). Results: The prevalence of hydrocephalus was 0.092% with a relative predominance among males. Conclusion: The study concluded that the prevalence of congenital hydrocephalus is comparable to that of developed countries. The efforts made by the Ministry of Health seem to have paid off. More research on stillbirths is recommended.
Cite this paper
Alebous, H. and Hasan, A. (2012) Prevalence of congenital hydrocephalus in the Hashemite kingdom of Jordan: A hospital-based study. Natural Science, 4, 789-791. doi: 10.4236/ns.2012.410104.
Alebous, H. and Hasan, A. (2012) Prevalence of congenital hydrocephalus in the Hashemite kingdom of Jordan: A hospital-based study. Natural Science, 4, 789-791. doi: 10.4236/ns.2012.410104.
References
[1] El-Salem, K. et al. (2006) Multiple sclerosis in Jordan: A clinical and epidemiological study. Journal of neurology, 253, 1210-1216. doi:10.1007/s00415-006-0203-2 [2] Al-Qutob, R. and Nasir, L. (2008) Provider perceptions of reproductive health service quality in Jordanian public community health centers. Health Care for Women International, 29, 539-550. doi:10.1080/07399330801949657 [3] Garne, E. et al. (2010) Congenital hydrocephalus-prevalence, prenatal diagnosis and outcome of pregnancy in four European regions. European journal of paediatric neurology, 14, 150-155. doi:10.1016/j.ejpn.2009.03.005 [4] Schrander-Stumpel, C. and Fryns, J.P. (1998) Congenital hydrocephalus: Nosology and guidelines for clinical approach and genetic counseling. European journal of pediatrics, 157, 355-362. doi:10.1007/s004310050830 [5] Sadler, T.W. (2010) Langman’s medical embryology. 11th Edition, Lippincott Williams & Wilkins, Baltimore. [6] Sun, G., Xu, Z.M., Liang, J.F., Li, L. and Tang, D.X. (2011) Twelve-year prevalence of common neonatal congenital malformations in Zhejiang Province, China. World journal of pediatrics, 7, 331-336. doi:10.1007/s12519-011-0328-y [7] Jeng, S., Gupta, N., Wrensch, M., Zhao, S. and Wu, Y.W. (2011) Prevalence of congenital hydrocephalus in California, 1991-2000. Pediatric neurology, 45, 67-71. doi:10.1016/j.pediatrneurol.2011.03.009 [8] Amarin, Z. and Obeidat, A. (2010) Effect of folic acid fortification on the incidence of neural tube defects. Paediatric and Perinatal Epidemiology, 24, 349-351. doi:10.1111/j.1365-3016.2010.01123.x [9] Miller, J.M. and McAllister, J.P. II. (2007) Reduction of astrogliosis and microgliosis by cerebrospinal fluid shunting in experimental hydrocephalus. Cerebrospinal fluid research, 4, 5. doi:10.1186/1743-8454-4-5 [10] Clewell, W.H. (1988) Congenital hydrocephalus: Treatment in utero. Fetaltherapy, 3, 89-97. [11] Kohn, D.F., Chinookoswong, N. and Chou, S.M. (1981) A new model of congenital hydrocephalus in the rat. Acta neuropathologica, 54, 211-218. doi:10.1007/BF00687744 [12] Christensen, J.H., Hansen, L.K. and Garne, E. (2003) Congenital hydrocephalus-prevalence and prognosis. Mortality and morbidity in a population-based study. Ugeskrift for laeger, 165, 466-469. [13] Dietrich, P., Shanmugasundaram, R., Shuyu, E. and Dragatsis, I. (2009) Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages. Human molecular genetics, 18, 142-150. doi:10.1093/hmg/ddn324 [14] Stoll, C., Alembik, Y., Dott, B. and Roth, M. (1992) An epidemiologic study of environmental and genetic factors in congenital hydrocephalus. European journal of epidemiology, 8, 797-803. doi:10.1007/BF00145322 [15] Shaw, G.M., Carmichael, S.L., Kaidarova, Z. and Harris, J.A. (2003) Differential risks to males and females for congenital malformations among 2.5 million California births, 1989-1997. Birth defects research. Part A, Clinical and molecular teratology, 67, 953-958. doi:10.1002/bdra.10129 [16] Cavalheiro, S. et al. (2011) Fetal hydrocephalus. official journal of the International Society for Pediatric Neurosugery, 27, 1575-1583.
[1] El-Salem, K. et al. (2006) Multiple sclerosis in Jordan: A clinical and epidemiological study. Journal of neurology, 253, 1210-1216. doi:10.1007/s00415-006-0203-2 [2] Al-Qutob, R. and Nasir, L. (2008) Provider perceptions of reproductive health service quality in Jordanian public community health centers. Health Care for Women International, 29, 539-550. doi:10.1080/07399330801949657 [3] Garne, E. et al. (2010) Congenital hydrocephalus-prevalence, prenatal diagnosis and outcome of pregnancy in four European regions. European journal of paediatric neurology, 14, 150-155. doi:10.1016/j.ejpn.2009.03.005 [4] Schrander-Stumpel, C. and Fryns, J.P. (1998) Congenital hydrocephalus: Nosology and guidelines for clinical approach and genetic counseling. European journal of pediatrics, 157, 355-362. doi:10.1007/s004310050830 [5] Sadler, T.W. (2010) Langman’s medical embryology. 11th Edition, Lippincott Williams & Wilkins, Baltimore. [6] Sun, G., Xu, Z.M., Liang, J.F., Li, L. and Tang, D.X. (2011) Twelve-year prevalence of common neonatal congenital malformations in Zhejiang Province, China. World journal of pediatrics, 7, 331-336. doi:10.1007/s12519-011-0328-y [7] Jeng, S., Gupta, N., Wrensch, M., Zhao, S. and Wu, Y.W. (2011) Prevalence of congenital hydrocephalus in California, 1991-2000. Pediatric neurology, 45, 67-71. doi:10.1016/j.pediatrneurol.2011.03.009 [8] Amarin, Z. and Obeidat, A. (2010) Effect of folic acid fortification on the incidence of neural tube defects. Paediatric and Perinatal Epidemiology, 24, 349-351. doi:10.1111/j.1365-3016.2010.01123.x [9] Miller, J.M. and McAllister, J.P. II. (2007) Reduction of astrogliosis and microgliosis by cerebrospinal fluid shunting in experimental hydrocephalus. Cerebrospinal fluid research, 4, 5. doi:10.1186/1743-8454-4-5 [10] Clewell, W.H. (1988) Congenital hydrocephalus: Treatment in utero. Fetaltherapy, 3, 89-97. [11] Kohn, D.F., Chinookoswong, N. and Chou, S.M. (1981) A new model of congenital hydrocephalus in the rat. Acta neuropathologica, 54, 211-218. doi:10.1007/BF00687744 [12] Christensen, J.H., Hansen, L.K. and Garne, E. (2003) Congenital hydrocephalus-prevalence and prognosis. Mortality and morbidity in a population-based study. Ugeskrift for laeger, 165, 466-469. [13] Dietrich, P., Shanmugasundaram, R., Shuyu, E. and Dragatsis, I. (2009) Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages. Human molecular genetics, 18, 142-150. doi:10.1093/hmg/ddn324 [14] Stoll, C., Alembik, Y., Dott, B. and Roth, M. (1992) An epidemiologic study of environmental and genetic factors in congenital hydrocephalus. European journal of epidemiology, 8, 797-803. doi:10.1007/BF00145322 [15] Shaw, G.M., Carmichael, S.L., Kaidarova, Z. and Harris, J.A. (2003) Differential risks to males and females for congenital malformations among 2.5 million California births, 1989-1997. Birth defects research. Part A, Clinical and molecular teratology, 67, 953-958. doi:10.1002/bdra.10129 [16] Cavalheiro, S. et al. (2011) Fetal hydrocephalus. official journal of the International Society for Pediatric Neurosugery, 27, 1575-1583.