OJU  Vol.2 No.3 A , October 2012
The Use of Bovine Collagen and Skin Graft for Reconstruction of the Glans Penis Following Cancer Resection
Abstract: Penile reconstruction following cancer resection has long been a challenge due to demand for both aesthetic and functional preservation. Although various methods have attempted to achieve both goals, none have succeeded entirely. In this report, we introduce a novel reconstructive technique on a 64-year-old patient with squamous cell carcinoma of the glans penis. The technique consisted of two staged procedures. First, a dermal substitute, consisting of bovine collagen, was sutured onto the defect after partial glansectomy and three weeks later, the integrated dermis was covered with autologous non-meshed partial thickness skin graft. Use of this dermal substitute in a staged fashion allowed for ability to await final pathologic margins prior to definitive reconstruction and increased dermal thickness. After 9-month follow-up, sexual function returned within 3 months and the patient remained healed. We found this technique to be useful in concurrently preserving penile function and cosmesis. Future studies should include more patients and longer follow-up.
Cite this paper: Z. Sun, V. R. Sinha, E. E. Young, B. Bensadigh, C. Ceron, B. R. Kava, J. N. Landon and C. J. Salgado, "The Use of Bovine Collagen and Skin Graft for Reconstruction of the Glans Penis Following Cancer Resection," Open Journal of Urology, Vol. 2 No. 3, 2012, pp. 216-218. doi: 10.4236/oju.2012.223038.

[1]   C. Lorenz, A. Petracic, H. P. Hohl, et al., “Early Wound Closure and Early Reconstruction. Experience with a Dermal Substitute in a Child with 60 Percent Surface Area Burn,” Burns, Vol. 23, No. 6, 1997, pp. 505-508.

[2]   S. Popescu, N. Ghetu, O. Grosu, et al., “Integra: A Therapeutic Alternative in Reconstructive Surgery. Our First Experience,” Chirurgia, Vol. 102, No. 2, 2007, pp. 197-204.

[3]   C. E. Payne, A. M. Williams and N. B. Hart, “Lotus Petal Flaps for Scrotal Reconstruction Combined with Integra Resurfacing of the Penis and Anterior Abdominal Wall Following Necrotizing Fasciitis,” Journal of Plastic, Reconstructive & Aesthetic Surgery, Vol. 62, No. 3, 2009, pp. 393-397.

[4]   A. D. Jaskille, J. W. Shupp, J. C. Jeng and M. H. Jordan, “Use of Integra in the Treatment of Third Degree Burns to the Penile Shaft: A Case Series with 6-Month Follow-Up,” Journal of Burn Care & Research, Vol. 30, 2009, pp. 524-528.

[5]   C. D. Knotts, A. L. Morgan and J. C. Deschamps-Braly, et al., “‘Mulching’ Integra for Glans Penis,” Plastic and Reconstructive Surgery, Vol. 126, No. 3, 2010, pp. 151e-152e.