W. D. Inman, M. O’Neill-Johnson and P. Crews, “Pyrroloacridine Alkaloids from Plakortis Quasiampkiaster: Structures and Bioactivity,” Journal of the American Chemical Society, Vol. 112, 1990, pp. 1-13.
  J. R. Goodell, A. A. Madhok and H. Hiasa, D. M. Fergusson, “Synthesis and Evaluation of Acridineand Acridone-Based Anti-herpes Agents with Topoisomerase Activity,” Bioorganic & Medicinal Chemistry, Vol. 14, No. 16, 2006, pp. 5467-5480.
  C. T. Lowden and K. F. Bastow, “Cell Culture Replication of Herpes Simplex Virus and, or Human Cytomegalovirus Is Inhibited by 3, 7-Dialkoxylated, 1-Hydroxyacridone Derivatives,” Antiviral Research, Vol. 59, No. 3, 2003, pp. 143-154.
  M. Itoigawa, C. Ito, T.-S. Wu, et al., “Cancer Chemopreventive Activity of Acridone Alkaloids on Epstein-Barr Virus Activation and Two-Stage Mouse Skin Carcinogenesis,” Cancer Letters, Vol. 193, No. 2, 2003, pp. 133138.
  V. V. Zarubaev, A. V. Slita, V. Z. Krivitskaya, A. K. Sirotkin, A. L. Kovalenko and N. K. Chatterjee, “Direct Antiviral Effect of Cycloferon (10-Carboxymethyl-9-Acridanone) against Adenovirus Type 6 in Vitro,” Antiviral Research, Vol. 58, No. 2, 2003, pp. 131-137.
  S. S. Claudia, L. F. Mirta, B. M. Maria, L. D. Maite, F. P. Rolando, C. G. Cybele, B. D. Norma and B. D. Elsa, “Synthesis and Evaluation of N-substituted Acridones as Antiviral Agents against Haemorrhagic Fever Viruses, Antiviral Chemistry & Chemotherapy,” Short Communications, Vol. 19, 2008, pp. 41-47.
  K. Dzierzbicka and A. M. kolodziejczyk, “Synthesis and Antitumor Activity of Conjugates of Muramyldipeptide, Normuramyldipeptide and Desmuramylpeptides with Acridine/Acridone Derivatives,” Journal of Medicinal Che-mistry, Vol. 44, No. 22, 2001, pp. 3606-3615.
  S. A. Gamage, J. A. Spicer, G. J. Atwell, G. J. Finlay, B. C. Baguley and W. A. Denny, “Structure-Activity Relationships for Substituted Bis(Acridine-4-Carboxamides): A New Class of Anticancer Agents,” Journal of Medicinal Chemistry, Vol. 42, No. 13, 1999, pp. 2383-2393.
  T. Bentin and P. E. Nielsen, “Superior Duplex DNA Strand Invasion by Acridine Conjugated Peptide Nucleic Acids,” Journal of the American Chemical Society, Vol. 125, No. 21, 2003, pp. 6378-6379.
  X. K. Jane, J. S. Martin, A. C. Roland, D. L. Kristin, A. J. Robert, J. Aaron, A. D. Rozalia, J. H. David, W. Rolf and R. Michael, “Design, Synthesis and Evaluation of 10-NSubstituted Acridones as Novel Chemosensitizers in Plasmodium Falciparum,” Antimicrobial Agents and Chemotherapy, Vol. 51, No. 11, 2007, pp. 4133-4140.
  L. L. Zhu, T. J. Hou, L. R. Chen and X. J. Xu, “3DQSAR Analyses of Novel Tyrosine Kinase Inhibitors Based on Pharmacophore Alignment,” Journal of Chemical Information and Modeling, Vol. 41, No. 4, 2001, pp. 1032-1040.
  R. D. Cramer, D. E. Patterson and J. D. Bunce, “Comparative Molecular Field Analysis (C0MFA). 1. Effect of Binding on Steroids to Carrier Proteins,” Journal of the American Chemical Society, Vol. 110, No. 18, 1988, pp. 5959-5967.
  Other Approaches Do Exist with Promising Direct 3D Database Searching with Potency Predictions, Such as Pseudo-Receptor Modeling, the Catalyst Suite, and Post3D-Searching CoMFA. However, They Are Limited in Speed, and Perhaps, Range of Applicability.
  Y. C. Martin, “3D QSAR: Current State, Scope and Limitations,” In: H. Kubinyi, G. Folkers and Y. C. Martin, Eds., Three-Dimensional Quantitative Structure Activity Relationships, Vol. 3, Springer, Netherlands, 2002, pp. 3-23.
  R. Bursi and P. D. G. Grootenhuis, “Comparative Molecular Field Analysis and Energy Interaction Studies of Thrombin-Inhibitor Complexes,” Journal of ComputerAided Molecular Design, Vol. 13, No. 3, 1999, pp. 221232.
  S. S. Sao and M. Karplus, “Evaluation of Design Ligands by Multiple Screening Method: Application of Glycogen Phosphorylase Inhibitors Constructed with a Variety of Approaches,” Journal of Computer-Aided Molecular Design, Vol. 15, No. 7, 2001, pp. 613-647.
  R. D. Cramer, R. D. Clark, D. E. Patterson and A. M. Fergusson, “Bioisosterism as a Molecular Diversity Descriptor: Steric Fields of Single ‘Topomeric’ Conformers,” Journal of Medicinal Chemistry, Vol. 39, No. 16, 1996, pp. 3060-3069.
  T. A. Halgren, “Merck Molecular Force Field V. Extension of MMFF94 Using Experimental Data, Additional computation Data, and Empirical Rules,” Journal of Computational Chemistry, Vol. 17, 1996, pp. 616-641.