OJMM  Vol.2 No.3 , September 2012
A Case Report: PCR-Assisted Diagnosis of Varicella in an Adult
ABSTRACT
A 41-year-old woman developed skin lesions on her upper back and arm. Initially, a definitive diagnosis could not be made. Subsequently, PCR detected VZV DNA in skin lesions and saliva. Immediate antiviral treatment led to a quick recovery without complicating prolonged fatigue and weakness typically seen in adults with varicella.

Cite this paper
S. Mehta, D. Gilden, B. Crucian, C. Sams, R. Cohrs and D. Pierson, "A Case Report: PCR-Assisted Diagnosis of Varicella in an Adult," Open Journal of Medical Microbiology, Vol. 2 No. 3, 2012, pp. 131-132. doi: 10.4236/ojmm.2012.23019.
References
[1]   S. K. Mehta, S. K. Tyring, D. H. Gilden, R. J. Cohrs, M. J. Leal, V. A. Castro, A. H. Feiveson, C. M. Ott and D. L. Pierson, “Varicella-Zoster Virus in the Saliva of Patients with Herpes Zoster,” The Journal of Infectious Diseases, Vol. 197, No. 5, 2008, pp. 654-657. Hdoi:10.1086/527420

[2]   V. N. Loparev, K. McCaustland, B. P. Holloway, P. R. Krause, M. Takayama and D. S. Schmid, “Rapid Genotyping of Varicella-Zoster Virus Vaccine and Wild-Type Strains with Fluorophore-Labeled Hybridization Probes,” Journal of Clinical Microbiology, Vol. 38, No. 12, 2000, pp. 4315-4319.

[3]   D. P. Depledge, A. L. Palser, S. J. Watson, I. Y. Lai, E. R. Gray, P. Grant, R. K. Kanda, E. Leproust, P. Kellam and J. Breuer, “Specific Capture and Whole-Genome Sequenceing of Viruses from Clinical Samples,” PLoS One, Vol. 6, No. 11, 2008, e27805. Hdoi:10.1371/journal.pone.0027805

[4]   Y. Furuta, F. Ohtani, H. Sawa, S. Fukuda and Y. Inuyama, “Quantitation of Varicella-Zoster Virus DNA in Patients with Ramsay Hunt Syndrome and Zoster Sine Herpete,” Journal of Clinical Microbiology, Vol. 39, No. 8, 2001, pp. 2856-2859. Hdoi:10.1128/JCM.39.8.2856-2859.2001

[5]   R. J. Cohrs, S. K. Mehta, D. S. Schmid, D. H. Gilden and D. L. Pierson, “Asymptomatic Reactivation and Shed of Infectious Varicella Zoster Virus in Astronauts,” Journal of Medical Virology, Vol. 80, No. 6, 2008, pp. 1116-1122. Hdoi:10.1002/jmv.21173

[6]   H. Q. Nguyen, A. O. Jumaan and J. F. Seward, “Decline in Mortality Due to Varicella after Implementation of Varicella Vaccination in the United States,” The New England Journal of Medicine, Vol. 352, No. 5, 2005, pp. 450-458. Hdoi:10.1056/NEJMoa042271

 
 
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