Health  Vol.2 No.7 , July 2010
Alternations in salivary glucose during ramadan fasting
Abstract: During the holly month of Ramadan, Muslims fast every day from dawn to sunset. Although the effect of Ramadan fasting on general health has been widely studied, the impact of fasting on oral health and possible changes in salivary biochemicals, such as glucose, has not received much attentiom. The aim of our study was to evaluate the influence of fasting on the level of glucose in the saliva of healthy individuals. Salivary glucose was measured using an enzymatic method based on oxidation of glucose by glucoseoxidase followed by determination of resulting H2O2 in the presence of peroxidase. A reduction in mean concentration of glucose was observed in the saliva of all fasting subjects as compared to the control group. It was concluded that reduction in salivary glucose is mostly due to reduced food intake and may be beneficial to dental health.
Cite this paper: nullSariri, R. , Varasteh, A. and Erfani, A. (2010) Alternations in salivary glucose during ramadan fasting. Health, 2, 769-772. doi: 10.4236/health.2010.27116.

[1]   Jr. Cahill, G.F. (1970) Starvation in men. The New England Journal of Medicine, 282, 668-675.

[2]   Herber D. (1995) Endocrine response to starvation, malnutrition, and illness. In: DeGroot Ly, Ed., Endocrinology, 3rd Edition, Saunders, Philadelphia, 2663-2678.

[3]   Azizi, F. (1996) Medical aspects of Islamic fasting. Iranian Journal of Medical Sciences, 10(1), 241-246.

[4]   Dodds, M.W.J., Johnson, D.A. and Yeh, C.K. (2005) Health benefits of saliva. Journal of Dentistry, 33(3), 223-233.

[5]   Lebanthal, E. (1987) Role of salivary amylase in gasteric and intestinal digestion of starch. Digestive Diseases and Sciences, 32(10), 1155-1157.

[6]   Tabak, L.A., Levine, M.J., Mandel, I.D. and Elison, L.A. (1982) Role of salivary mucins in the protection of the oral cavity. Journal of Oral Pathology & Medicine, 11(1), 1-7.

[7]   Kohen, R., Tirosh, O. and Kopolovich, K. (1992) The reductive capacity index of saliva obtained from donors of various ages. Experimental Gerontology, 27(2), 161- 68.

[8]   Nagler, R., Lischnisky, S., Diamond, E., et al. (2000) Effect of cigarette smoke on salivary proteins and enzyme activeties. Archives of Biochemistry and Biophysics, 379(2), 229-236.

[9]   Zappacosta B., Persichilli S., Mordente, A., et al. (2002) Inhibition of salivary enzymes by cigarette smoke and protecttive role of glutathione. Human and Experimental Toxcology, 21(1), 7-11.

[10]   Azizi, F. and Rasouli, H.A. (1987) Serum glucose, biliru- bin, calcium, phosphorus, protein and albumin concen- trations during Ramadan. Iranian Journal of Medical Sciences, 1, 38-41.

[11]   Haouri, M., Haourai-Oukerro, F., Mebazaa, A. and Nagati, K. (1997) Circadian evolution of serum level of glucose, insulin, cortisol and total proteins in healthy, fasting volunteers. Second International Congress on Health and Ramadan, Istanbul, 31.

[12]   Scott, T.G. (1994) The effect of Muslim fast of Ramadan on routine laboratory investigation. Journal of King Abdulaziz University, 1(4), 23-35.

[13]   Bagraicik, N., Yumuk, V., Damei, T. and Ozyazar, M. (1992) The effect of fasting on blood glucose, fructosamine, insulin and C-peptide levels in Ramadan. First International Congress on Health and Ramadan. Casablanca, Morocco, 32.

[14]   Sajid, K.M., Akhtar, M. and Malik, G.Q. (1991) Ramadan fasting and thyroid hormone profile. Juvenile Products Manufacturers Association, 41(9), 213-216.

[15]   Sulimani, R.A. (1988) Effect of Ramadan fasting on thyroid function in healthy male individuals. Nutrition Research, 8(5), 549-552.

[16]   Shoukry, M.I. (1986) Effect of fasting in Ramadan on plasma lipoproteins and apoproteins. Saudi Medical Journal, 7(6), 561-567.

[17]   Mayes, P.A. (2000) Digestion and absorption. Harpers, Biochemistry, In: R.K. Murray, D.K. Granner, P.A. Mayes and V.W. Rodwell, Eds., 25th Edtion, Appleton and Lange, New York, 666-674.

[18]   Negoro, M., et al. (2000) Oral glucose retention, saliva viscosity and flow rate in 5-year-old children. Archives of Oral Biology, 45(1), 1005-1011.