Asthma and Injury Risk: A Large Scale Population-Based Study
Affiliation(s)
Politecnico National Drug Research Institute, Curtin University, Perth, Western Australia, Australia.
Politecnico National Drug Research Institute, Curtin University, Perth, Western Australia, Australia.
ABSTRACT
Purpose: Clinical data suggest that asthma impairs sleep quality and further impairs cognitive performance during the daytime, while there is a causal relationship between impaired sleep quality and injuries. Therefore asthma patients may have increased risk of injury, and this is supported by our recent population-based studies conducted in Australia. This study is to investigate the effect of asthma on the risk of injury at the population level using data from the U.S. National Health Interview Survey collected in 2008, 2009, and 2010. Method: Data from the 2008, 2009 and 2010 National Health Interview Surveys were combined and analyzed together. Results: U.S. adults with current or previous asthma had significantly greater risk of injury compared to those without asthma. The risk of injury was also significantly higher among children with current asthma. Conclusion: This population-based study provided further evidence on the positive association between asthma and risk of injury among both adults and children. The increased risk of injury among asthma patients is at least partly due to impaired sleep quality and quantity caused by asthma symptoms and asthma medications.
Purpose: Clinical data suggest that asthma impairs sleep quality and further impairs cognitive performance during the daytime, while there is a causal relationship between impaired sleep quality and injuries. Therefore asthma patients may have increased risk of injury, and this is supported by our recent population-based studies conducted in Australia. This study is to investigate the effect of asthma on the risk of injury at the population level using data from the U.S. National Health Interview Survey collected in 2008, 2009, and 2010. Method: Data from the 2008, 2009 and 2010 National Health Interview Surveys were combined and analyzed together. Results: U.S. adults with current or previous asthma had significantly greater risk of injury compared to those without asthma. The risk of injury was also significantly higher among children with current asthma. Conclusion: This population-based study provided further evidence on the positive association between asthma and risk of injury among both adults and children. The increased risk of injury among asthma patients is at least partly due to impaired sleep quality and quantity caused by asthma symptoms and asthma medications.
Cite this paper
W. Liang and T. Chikritzhs, "Asthma and Injury Risk: A Large Scale Population-Based Study," International Journal of Clinical Medicine, Vol. 3 No. 5, 2012, pp. 394-399. doi: 10.4236/ijcm.2012.35074.
W. Liang and T. Chikritzhs, "Asthma and Injury Risk: A Large Scale Population-Based Study," International Journal of Clinical Medicine, Vol. 3 No. 5, 2012, pp. 394-399. doi: 10.4236/ijcm.2012.35074.
References
[1] Eder, W., Ege, M.J., and von Mutius, E. (2006) Current concepts: The asthma epidemic. New England Journal of Medicine, 355(21), 2226-2235. [2] Russell, G. (2006) The childhood asthma epidemic. Thorax, 61(4), 276-278. [3] Peters, S.P., Ferguson, G., Deniz, Y., and Reisner, C. (2006) Uncontrolled asthma: A review of the prevalence, disease burden and options for treatment. Respiratory Medicine, 100(7), 1139-1151. [4] Masoli, M., Fabian, D., Holt, S., and Beasley, R. (2004) The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy, 59(5), 469-78. [5] WHO, Global surveillance, prevention and control of chronic respiratory diseases: a comprehensive approach. 2007, World Health Organization: Switzerland. [6] Diette, G.B., Markson, L., Skinner, E.A., Nguyen, T.T.H., Algatt-Bergstrom, P., and Wu, A.W. (2000) Nocturnal Asthma in Children Affects School Attendance, School Performance, and Parents' Work Attendance. Arch Pediatr Adolesc Med, 154(9), 923-928. [7] Fitzpatrick, M.F., Engleman, H., Whyte, K.F., Deary, I.J., Shapiro, C.M., and Douglas, N.J. (1991) Morbidity in nocturnal asthma: sleep quality and daytime cognitive performance. Thorax, 46(8), 569-573. [8] Teodorescu, M., Consens, F.B., Bria, W.F., Coffey, M.J., McMorris, M.S., Wea-therwax, K.J., et al. (2006) Correlates of daytime sleepiness in patients with asthma. Sleep Medicine, 7(8), 607-613. [9] Janson, C., De Backer, W., Gislason, T., Plaschke, P., Bjornsson, E., Hetta, J., et al. (1996) Increased prevalence of sleep disturbances and daytime sleepiness in subjects with bronchial asthma: a population study of young adults in three European countries. European Respiratory Journal, 9(10), 2132-2138. [10] Campos, F.L., da Silva-Júnior, F.P., de Bruin, V.M.S., and de Bruin, P.F.C. (2004) Melatonin Improves Sleep in Asthma. American Journal of Respiratory and Critical Care Medicine, 170(9), 947-951. [11] Daley, M., Morin, C.M., LeBlanc, M., Grégoire, J.P., Savard, J., and Baillargeon, L. (2009) Insomnia and its relationship to health-care utilization, work absenteeism, productivity and accidents. Sleep Medicine, 10(4), 427-438. [12] Owens, J.A., Fernando, S., and Mc Guinn, M. (2005) Sleep Disturbance and Injury Risk in Young Children. Behavioral Sleep Medicine, 3(1), 18-31. [13] Adinoff, A.D. and Hollister, J.R. (1983) Steroid-Induced Fractures and Bone Loss in Patients with Asthma. New England Journal of Medicine, 309(5), 265-268. [14] Dahl, R. (2006) Systemic side effects of inhaled corticosteroids in patients with asthma. Respiratory Medicine, 100(8), 1307-1317. [15] Liang, W., Chikritzhs, T., and Lee, A.H. (2011) Is Asthma Associated with Increased Risk of Injury? Journal of Asthma. [16] Liang, W., Chikritzhs, T., and Lee, A.H. (2011) Asthma and risk of injury for Australian males aged 6-30 years: a population-based birth cohort study. J Asthma, 48(7), 736-40. [17] CDC, 2010 NHIS Survey Description. 2011, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services: Maryland, United States. [18] CDC, 2008 NHIS Survey Description. 2009, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services: Maryland, United States. [19] CDC, 2009 NHIS Survey Description. 2010, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services: Maryland, United States. [20] Xiang, H.Y., Stallones, L., Chen, G.M., Hostetler, S.G., and Kelleher, K. (2005) Nonfatal injuries among US children with disabling conditions. American Journal of Public Health, 95(11), 1970-1975. [21] Lee, L.-C., Harrington, R.A., Chang, J.J., and Connors, S.L. (2007) Increased risk of injury in children with developmental disabilities. Research in Developmental Disabilities, 29(3), 247-255. [22] Schwebel, D.C. and Brezausek, C.M. (2009) Injury Risk in Children with Asthma. Journal of Asthma, 46(6), 560-563. [23] Janson, C., Gislason, T., Boman, G., Hetta, J., and Roos, B.E. (1990) Sleep disturbances in patients with asthma. Respir Med, 84(1), 37-42. [24] Klink, M.E., Dodge, R., and Quan, S.F. (1994) The relation of sleep complaints to respiratory symptoms in a general population. Chest, 105(1), 151-4. [25] Mastronarde, J.G., Wise, R.A., Shade, D.M., Olopade, C.O., Scharf, S.M., and Centers, f.t.A.L.A.A.C.R. (2008) Sleep Quality in Asthma: Results of a Large Prospective Clinical Trial. Journal of Asthma, 45(3), 183-189. [26] Melamed, S. and Oksenberg, A. (2002) Excessive daytime sleepiness and risk of occupational injuries in non-shift daytime workers. Sleep, 25(3), 315-22. [27] Terán-Santos, J., Jimenez-Gomez, A., and Cor-dero-Guevara, J. (1999) The Association between Sleep Apnea and the Risk of Traffic Accidents. New England Journal of Medicine, 340(11), 847-851. [28] Gold, D.R., Rogacz, S., Bock, N., Tosteson, T.D., Baum, T.M., Speizer, F.E., et al. (1992) Rotating shift work, sleep, and accidents related to sleepiness in hospital nurses. American Journal of Public Health, 82(7), 1011-1014. [29] Valent, F., Brusaferro, S., and Barbone, F. (2001) A Case-Crossover Study of Sleep and Childhood Injury. Pediatrics, 107(2), e23.
[1] Eder, W., Ege, M.J., and von Mutius, E. (2006) Current concepts: The asthma epidemic. New England Journal of Medicine, 355(21), 2226-2235. [2] Russell, G. (2006) The childhood asthma epidemic. Thorax, 61(4), 276-278. [3] Peters, S.P., Ferguson, G., Deniz, Y., and Reisner, C. (2006) Uncontrolled asthma: A review of the prevalence, disease burden and options for treatment. Respiratory Medicine, 100(7), 1139-1151. [4] Masoli, M., Fabian, D., Holt, S., and Beasley, R. (2004) The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy, 59(5), 469-78. [5] WHO, Global surveillance, prevention and control of chronic respiratory diseases: a comprehensive approach. 2007, World Health Organization: Switzerland. [6] Diette, G.B., Markson, L., Skinner, E.A., Nguyen, T.T.H., Algatt-Bergstrom, P., and Wu, A.W. (2000) Nocturnal Asthma in Children Affects School Attendance, School Performance, and Parents' Work Attendance. Arch Pediatr Adolesc Med, 154(9), 923-928. [7] Fitzpatrick, M.F., Engleman, H., Whyte, K.F., Deary, I.J., Shapiro, C.M., and Douglas, N.J. (1991) Morbidity in nocturnal asthma: sleep quality and daytime cognitive performance. Thorax, 46(8), 569-573. [8] Teodorescu, M., Consens, F.B., Bria, W.F., Coffey, M.J., McMorris, M.S., Wea-therwax, K.J., et al. (2006) Correlates of daytime sleepiness in patients with asthma. Sleep Medicine, 7(8), 607-613. [9] Janson, C., De Backer, W., Gislason, T., Plaschke, P., Bjornsson, E., Hetta, J., et al. (1996) Increased prevalence of sleep disturbances and daytime sleepiness in subjects with bronchial asthma: a population study of young adults in three European countries. European Respiratory Journal, 9(10), 2132-2138. [10] Campos, F.L., da Silva-Júnior, F.P., de Bruin, V.M.S., and de Bruin, P.F.C. (2004) Melatonin Improves Sleep in Asthma. American Journal of Respiratory and Critical Care Medicine, 170(9), 947-951. [11] Daley, M., Morin, C.M., LeBlanc, M., Grégoire, J.P., Savard, J., and Baillargeon, L. (2009) Insomnia and its relationship to health-care utilization, work absenteeism, productivity and accidents. Sleep Medicine, 10(4), 427-438. [12] Owens, J.A., Fernando, S., and Mc Guinn, M. (2005) Sleep Disturbance and Injury Risk in Young Children. Behavioral Sleep Medicine, 3(1), 18-31. [13] Adinoff, A.D. and Hollister, J.R. (1983) Steroid-Induced Fractures and Bone Loss in Patients with Asthma. New England Journal of Medicine, 309(5), 265-268. [14] Dahl, R. (2006) Systemic side effects of inhaled corticosteroids in patients with asthma. Respiratory Medicine, 100(8), 1307-1317. [15] Liang, W., Chikritzhs, T., and Lee, A.H. (2011) Is Asthma Associated with Increased Risk of Injury? Journal of Asthma. [16] Liang, W., Chikritzhs, T., and Lee, A.H. (2011) Asthma and risk of injury for Australian males aged 6-30 years: a population-based birth cohort study. J Asthma, 48(7), 736-40. [17] CDC, 2010 NHIS Survey Description. 2011, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services: Maryland, United States. [18] CDC, 2008 NHIS Survey Description. 2009, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services: Maryland, United States. [19] CDC, 2009 NHIS Survey Description. 2010, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services: Maryland, United States. [20] Xiang, H.Y., Stallones, L., Chen, G.M., Hostetler, S.G., and Kelleher, K. (2005) Nonfatal injuries among US children with disabling conditions. American Journal of Public Health, 95(11), 1970-1975. [21] Lee, L.-C., Harrington, R.A., Chang, J.J., and Connors, S.L. (2007) Increased risk of injury in children with developmental disabilities. Research in Developmental Disabilities, 29(3), 247-255. [22] Schwebel, D.C. and Brezausek, C.M. (2009) Injury Risk in Children with Asthma. Journal of Asthma, 46(6), 560-563. [23] Janson, C., Gislason, T., Boman, G., Hetta, J., and Roos, B.E. (1990) Sleep disturbances in patients with asthma. Respir Med, 84(1), 37-42. [24] Klink, M.E., Dodge, R., and Quan, S.F. (1994) The relation of sleep complaints to respiratory symptoms in a general population. Chest, 105(1), 151-4. [25] Mastronarde, J.G., Wise, R.A., Shade, D.M., Olopade, C.O., Scharf, S.M., and Centers, f.t.A.L.A.A.C.R. (2008) Sleep Quality in Asthma: Results of a Large Prospective Clinical Trial. Journal of Asthma, 45(3), 183-189. [26] Melamed, S. and Oksenberg, A. (2002) Excessive daytime sleepiness and risk of occupational injuries in non-shift daytime workers. Sleep, 25(3), 315-22. [27] Terán-Santos, J., Jimenez-Gomez, A., and Cor-dero-Guevara, J. (1999) The Association between Sleep Apnea and the Risk of Traffic Accidents. New England Journal of Medicine, 340(11), 847-851. [28] Gold, D.R., Rogacz, S., Bock, N., Tosteson, T.D., Baum, T.M., Speizer, F.E., et al. (1992) Rotating shift work, sleep, and accidents related to sleepiness in hospital nurses. American Journal of Public Health, 82(7), 1011-1014. [29] Valent, F., Brusaferro, S., and Barbone, F. (2001) A Case-Crossover Study of Sleep and Childhood Injury. Pediatrics, 107(2), e23.