ABSTRACT Eye movements play an important role in attention and visual processing. However, the manner in which eye move-ments are involved in object processing is not clear. The aim of this study is to examine the effects of eye movements on object-processing areas in the occipito-temporal region. Eye movements are always accompanied by visual perception; therefore, the effects of eye movements on object-processing areas in which visual object information is sent via eye movements instead of via retinal inputs of visual images must be measured. For this purpose, response to an eye- drawing stimulation in subjects who drew pictures of faces or buildings by their moving eyes under closed-eye condi-tions was measured by functional magnetic resonance imaging. Functional areas in the occipito-temporal region showed negative responses to the eye-drawing stimulation, and the pattern of negative activation maps in the region was almost the same as that of positive activation maps observed after visual image stimulation. Responses in cate-gory-selective area showed category dependency to the eye-drawing stimulation. This suggests that eye movements provide inhibitory inputs to the object-processing areas in the occipito-temporal region, and these inputs may modulate visual inputs to these areas coming through the retina in the visual perception process.
Cite this paper
Y. Sung, H. Tsubokawa, Y. Kim and S. Ogawa, "Eye Movements Provide Inhibitory Inputs to the Occipito-Temporal Region," Open Journal of Medical Imaging, Vol. 2 No. 3, 2012, pp. 85-89. doi: 10.4236/ojmi.2012.23015.
 D. Noton and L. W. Stark, “Scanpaths in Eye Movements during Pattern Perception,” Science, Vol. 171, No. 3968, 1971, pp. 308-311. doi:10.1126/science.171.3968.308
 I. A. Rybak, V. I. Gusakova, A. V. Golovan, L. N. Podladchikova and N. A. Shevtsova, “A Model of AttentionGuided Visual Perception and Recognition,” Vision Research, Vol. 38, No. 15-16, 1998, pp. 2387-2400.
 M. Rucci, R. Iovin, M. Poletti and F. Santini, “Miniature Eye Movements Enhance Fine Spatial Detail,” Nature, Vol. 447, No. 7146, 2007, pp. 851-854.
 L. Saether, W. Van Belle, B. Laeng T. Brennen and M. Overvoll, “Anchoring Gaze When Categorizing Faces’ Sex: Evidence from Eye-Tracking Data,” Vision Research, Vol. 49, No. 23, 2009, pp. 2870-2880.
 Z. M. Hafed and R. J. Krauzlis, “Ongoing Eye Movements Constraint Visual Perception,” Nature Neuroscience, Vol. 9, No. 11, 2006, pp. 1449-1457.
 B. Laeng and D.-S. Teodorescu, “Eye Scanpaths during Visual Imagery Reenact Those of Perception of the Same Visual Scene,” Cognitive Science, Vol. 26, No. 2, 2002, pp. 207-231. doi:10.1207/s15516709cog2602_3
 S. Brandt and L. W. Stark, “Spontaneous Eye Movements during Visual Imagery Reflect the Content of the Visual Scene,” Journal of Cognitive Neuroscience, Vol. 9, No. 1, 1997, pp. 27-38. doi:10.1162/jocn.19184.108.40.206
 R. A. Epstein and N. A. Kanwisher, “A Cortical Representtation of the Local Visual Environment,” Nature, Vol. 391, No. 6676, 1998, pp. 598-601. doi:10.1038/33402
 M. L. Gomo-Tempini and C. J. Price, “Identification of Famous Faces and Buildings,” Brain, Vol. 124, No. 19, 2001, pp. 2087-2097. doi:10.1093/brain/124.10.2087
 K. Grill-Spector, “The Neural Basis of Object Perception,” Current Opinion in Neurobiology, Vol. 13, No. 2, 2003, pp. 159-166. doi:10.1016/S0959-4388(03)00040-0
 N. Kanwisher, J. McDermott and M. M. Chun, “The Fusiform Face Area: A Module in Human Extrastriate Cortex Specialized for Face Perception,” Journal of Neuroscience, Vol. 17, No. 11, 1997, pp. 4302-4311.
 Y. Sung and S. Ogawa, “A Property of Face Representation at the Categorical Level,” Neuroscience Letters, Vol. 448, No. 1, 2008, pp. 1-5.
 C. Summerfield, E. Egner, M. Greene, E. Koechlin, J. Mangels and J. Hirsch, “Predictive Codes for Forthcoming Perception in the Frontal Cortex,” Science, Vol. 314 No. 5803, 2006, pp. 1311-1314.
 M. D. Fox and M. E. Raichle, “Spontaneous Fluctuations in Brain Activity Observed with Functional Magnetic Resonance Imaging,” Nature Reviews Neuroscience, Vol. 8, No. 9, 2007, pp. 700-711.