OJOG  Vol.2 No.3 , September 2012
Heterotopic tubal pregnancy with live twin birth complicating ovulation induction assisted cycle
Abstract: Heterotopic pregnancy is an uncommon clinical entity in Nigeria even though some of the risk factors are highly prevalent in the population. We report a case of heterotopic pregnancy following ovulation induction with clomiphene citrate. A favourable outcome resulting in live twin birth was recorded despite the presence of poor clinical features that affects pregnancy and foetal outcome.
Cite this paper: Adesiyun, A. and Ayodele-Cole, B. (2012) Heterotopic tubal pregnancy with live twin birth complicating ovulation induction assisted cycle. Open Journal of Obstetrics and Gynecology, 2, 325-327. doi: 10.4236/ojog.2012.23068.

[1]   Lemus, J.F. (2000) Ectopic pregnancy: An update. Current Opinion in Obstetrics and Gynecology, 12, 369-375. doi:10.1097/00001703-200010000-00005

[2]   Eigbefoh, J.O., Mabayoje, P.S. and Aliyu, J.A.Y. (2008) Heterotopic pregnancy: A report of two cases. Nigerian Journal of Clinical Practice, 11, 85-87.

[3]   Bright, D.A. and Gaupp, F.B. (1990) Hetertopic pregnancy: A reevaluation. The Journal of the American Board of Family Medicine, 3, 125-128.

[4]   Han, S.H., Jee, B.C., Suh, C.S., Kim, S.H., Choi, Y.M., Kim, J.G. and Moon, S.Y. (2007) Clinical outcomes of tubal heterotopic pregnancy, assisted vs spontaneous conceptions. Gynecologic and Obstetric Investigation, 64, 49-54.

[5]   Dor, J., Seidman, D.S., Levran, D., Ben-Rafael, Z., Ben Shlomo, I. and Mashiach, S. (1991) The incidence of combined intrauterine and extrauterine pregnancy after in vitro fertilization and embryo transfer. Fertility and Sterility, 55, 833-834.

[6]   Marcus, S.F., Macnamee, M. and Brinsden, P. (1995) Heterotopic pregnancies after in-vitro fertilization and embryo transfer. Human Reproduction, 10, 1232-1236. doi,10.1093/humrep/10.1.199

[7]   Tal, J., Haddad, S., Gordon, N. and Timor-Tritsch, I. (1996) Heterotopic pregnancy after ovulation induction and assisted reproductive technology, a literature review from 1971 to 1993. Fertility and Sterility, 66, 1-12.

[8]   Reeece, E.A., Petrie, R.H., Sirmans, M.F., Finster, M. and Todd, W.D. (1983) Combined intrauterine and extrauterine gestations, a review. American Journal of Obstetrics & Gynecology, 146, 323-330.

[9]   Adesiyun, A.G., Cole, G. and Ogwuche, P. (2009) Hydrotubation in the management of female infertility, outcome in low resource setting. East African Medical Journal, 86, 31-36. doi,10.4314/eamj.v86i1.46925

[10]   Seoud, M.A. (1992) Outcome of twin, triplet and quadruplet in in-vitro fertilization pregnancies, the Norfolk experience. Fertility and Sterility, 57, 825-834.

[11]   Mcdonald, S., Murphy, K., Beyene, J. and Ohlsson, A. (2005) Perinatal outcomes of in vitro fertilization twins, a systematic review and meta-analyses. American Journal of Obstetrics & Gynecology, 193, 141-152. doi,10.1016/j.ajog.2004.11.064

[12]   Goleman, G.A., Fisch, B., Ovadia, J. and Tadir, Y. (1992) Heterotopic pregnancies after assisted reproductive technologies. Obstetrical & Gynecological Survey, 47, 217-221. doi,10.1097/00006254-199204000-00001

[13]   Talo, C.P. (1995) Maternal and neonatal morbidity associated with in vitro fertilization. The Journal of Pediatrics, 5, 794-800. doi,10.1016/S0022-3476(95)70175-3

[14]   Smith, D.J.H. and Siddique, F.H. (1970) A case of heterotopic pregnancy. American Journal of Obstetrics & Gynecology, 108, 1289-1290.

[15]   Rojansky, N. and Schenker, J.G. (1996) Heterotopic pregnancy and assisted reproduction—An update. Journal of Assisted Reproduction and Genetics, 13, 594-601. doi:10.1007/BF02066615