AJAC  Vol.3 No.8 , August 2012
Evaluation of Pesticide Residues in Human Blood Samples of Agro Professionals and Non-Agro Professionals
Abstract: The aim of the present study was to evaluate the pesticide residues in human blood samples of volunteers related to Hyderabad and Mirpurkhas districts, Pakistan. The volunteers of both districts were divided into four groups on the basis of their exposure period to pesticides i.e. Group A-5 to 9 years, Group B-10 to 14 years, Group C-15 to19 years and Group D-above 20 years. Out of total 188 volunteers, 145 volunteers (77.1%) were agro–professionals and 43 volun- teers (32.9%) were non–agro professionals. Chlorpyrifos, endosulfan, 1, 1, 1-trichloro-2, 2-bis (p-chorophenyl) ethane (p,p'-DDT) and parathion residues were detected in many samples. The predominant pesticides found in blood samples of both district volunteers were chlorpyrifos (with highest mean concentration of 0.37 mg kg-1 in the D group of Mirpurkhas) and endosulfan (with highest mean concentration of 0.30 mg kg-1 in the D group of Hyderabad). The quantity of pesticide residues detected in some blood samples of agro-professionals were found to be at the alarming level.
Cite this paper: Y. Latif, S. Sherazi, M. Bhanger and S. Nizamani, "Evaluation of Pesticide Residues in Human Blood Samples of Agro Professionals and Non-Agro Professionals," American Journal of Analytical Chemistry, Vol. 3 No. 8, 2012, pp. 587-595. doi: 10.4236/ajac.2012.38077.

[1]   H. B. Mathur, H. C. Agarwal, S. Johnson, et al., “Analysis of Pesticide Residues in Blood Samples from Villages of Punjab,” CSE/PML/PR-21, 2005.

[2]   J. Rothlein, D. Rohlman, M. Lasarev, et al., “Organophosphate Pesticide Exposure and Neurobehavioral Performance in Agricultural and Non-Agricultural Hispanic Workers,” Environmental Health Perspectives, Vol. 114, No. 5, 2006, pp. 691-696. Hdoi:10.1289/ehp.8182

[3]   Y. Latif, S. T. H. Sherazi and M. I. Bhanger, “Assessment of Pesticide Residues in Some Fruits Using Gas Chromatography Coupled with Micro Electron Capture Detector,” Pakistan Journal of Analytical and Environmental Chemistry, Vol. 1-2, 2011, pp. 76-87.

[4]   B. D. Banerjee, V. Seth, A. Bhattacharya, et al., “Biochemical Effects of Some Pesticides on Lipid Peroxidation and Free-Radical Scavengers,” Toxicology Letters, Vol. 107, No. 1-3, 1999, pp. 33-47. Hdoi:10.1016/S0378-4274(99)00029-6

[5]   M. Iscan, T. Coban, I. Cok, et al., “The Organochlorine Pesticide Residues and Antioxidant Enzyme Activities in Human Breast Tumors: Is There Any Association?” Breast Cancer Research and Treatment, Vol. 72, No. 2, 2002, pp. 173-182. Hdoi:10.1023/A:1014828705281

[6]   M. S. Wolff, A. Zeleniuch-Jacquotte, N. Dubin, et al., “Risk of Breast Cancer and Organochlorine Exposure,” Cancer Epidemiology Biomarkers and Preventation, Vol. 9, No. 3, 2000, pp. 271-277.

[7]   J. M. Safi, “Association between Chronic Exposure to Pesticides and Recorded Cases of Human Malignancy in Gaza Governorates (1990-1999),” Science of the Total Envi-ronment, Vol. 284, No. 1-3, 2002, pp. 75-84. Hdoi:10.1016/S0048-9697(01)00868-3

[8]   M. A. Azmi, S. N. H. Naqvi, M. A. Azmi, et al., “Effect of Pesticide Residues on Health and Different Enzyme Levels in the Blood of Farm Workers from Gadap (Rural Area) Karachi, Pakistan,” Chemo-sphere, Vol. 64, No. 10, 2006, pp. 1739-1744. Hdoi:10.1016/j.chemosphere.2006.01.016

[9]   Y. Latif, S. T. H, Sherazi and M. I. Bhanger, “Assessment of Pesticide Residues in Commonly Used Vegetables in Hyderabad, Pakistan,” Eco-toxicology and Environmental Safety, Vol. 74, No. 8, 2011, pp. 2299-2303. Hdoi:10.1016/j.ecoenv.2011.07.030

[10]   Y. Latif, S. T. H. Sherazi and M. I. Bhanger, “Monitoring of Pesticide Residues in Commonly Used Fruits in Hyderabad Region, Pakistan,” American Journal of Analytical Chemistry, Vol. 2, No. 8, 2011, pp. 46-52. Hdoi:10.4236/ajac.2011.228123

[11]   Codex Alimentarius Commission (CODEX), “Report of the Twenty-Seven Session,” Geneva, 28 June-3 July 2004.

[12]   M. A. Azmi, S. N. H. Naqvi and M. A. Azmi, “Pesticide Residue in the Blood of Rural Population from Gadap, Karachi and Related Health Hazards,” Journal of Experimental Zoology India, Vol. 8, 2005, pp. 343-351.

[13]   S. Cruz, C. Lino and M. I. Silveira, “Evaluation of Organochlorine Pesticide Residues in Human Serum from an Urban and Two Rural Populations in Portugal,” Science of the Total Environment, Vol. 317, No. 1-3, 2003, pp. 23-35. Hdoi:10.1016/S0048-9697(03)00334-6