Health  Vol.4 No.7 , July 2012
Normal values of heart rate variability at rest in a young, healthy and active Mexican population
Abstract: This study analyzed Heart Rate Variability in a large sample of active young subjects within a narrow age range (18 to 25), using time and frequency domain methods and a Poincaré plot. Heart rate was recorded (beat to beat) for 30 minutes at rest in 200 healthy subjects divided into 4 groups: 50 sportsmen (20.54 ± 1.52 years); 50 active men (21.22 ± 1.31 years); 50 sportswomen (20.10 ± 1.87 years) and 50 active women (20.92 ± 1.87 years). Significant differences were found for most parameters between athletes and active subjects (male and female) but not between genders. Percentile distributions were provided for all parameters (according to gender and physical activity level) to be used as references in future researches.
Cite this paper: Corrales, M. , Torres, B. , Esquivel, A. , Salazar, M. and Naranjo Orellana, J. (2012) Normal values of heart rate variability at rest in a young, healthy and active Mexican population. Health, 4, 377-385. doi: 10.4236/health.2012.47060.

[1]   Kaplan, D.T., Furab, M.L., Pincus, S.M., Ryan, S.M., Lipsitz, L.A. and Goldberger, A.L. (1991) Aging and the complexity of cardiovascular dynamics. Biophysical Journal, 59, 945-949. doi:10.1016/S0006-3495(91)82309-8

[2]   Pikkujamsa, S.M., Makikallio, T.H., Sourander, L.B., Raiha, I.J., Puukka, P., Skytta, J., Peng, C.K., Golberger, A.L. and Huikuri, H.V. (1999) Cardiac interbeat interval dynamics from childhood to senescence: Comparison of conventional and new measures based on fractals and chaos theory. Circulation, 100, 393-399. doi:10.1161/01.CIR.100.4.393

[3]   Stein, P.H.S., Kleiger, R.E. and Rottman, J.N. (1997) Differing effects of age on heart rate variability in men and women. American Journal of Cardiology, 80, 302-305. doi:10.1016/S0002-9149(97)00350-0

[4]   Sinnreich, S., Kart, J.D., Friedlander, Y., Sapoznikov, D. and Luria, M.H. (1998) Five minutes recordings of heart rate variability for population studies: Repeatability and age-sex characteristics. Heart, 80, 156-162.

[5]   Zhang, J. (2007) Effect of age and sex on heart rate variability in healthy subjects. Journal of Manipulative and Physiological Therapeutics, 30, 374-379. doi:10.1016/j.jmpt.2007.04.001

[6]   Carter, J.B., Banister, E.W. and Blaber, A.P. (2007) The effect of age and gender on heart rate variability after endurance training. Medicine & Science in Sports & Exer- cise, 35, 1333-1340. doi:10.1249/01.MSS.0000079046.01763.8F

[7]   Huikuiri, H.V., Pikkuj?msa, S.M., Airaksinen, K.E.J., Ikaheimo, M.J., Rantala, A.O., Kauma, H., Lilja, M. and Kesaniemi, Y.A. (1996) Sex-related differences in autonomic modulation of heart rate in middle-aged subjects. Circulation, 94, 122-125. doi:10.1161/01.CIR.94.2.122

[8]   Ramaekers, D., Ector, H., Aubert, A.E., Rubens, A. and Werf, Van de F. (1998) Heart rate variability and heart rate in healthy volunteers. Is the female autonomic nervous system cardioprotective? European Heart Journal, 19, 1334-1341. doi:10.1053/euhj.1998.1084

[9]   Cruz, De la B., López, C. and Naranjo, J. (2008) Analysis of heart rate variability at rest and during aerobic exercise. A study in healthy people and cardiac patients. British Journal of Sports Medicine, 42, 715-720.

[10]   Bernardi, L., Ricordi, L., Lazzari, P., Soldá, P., Calciati, A., Ferrari, M.R., Vandea, I., Finardi, G. and Frantino, P. (1992) Impaired circadian modulation of sympathovagal activity in diabetes. Circulation, 86, 1443-1452. doi:10.1161/01.CIR.86.5.1443

[11]   Guzzetti, S., Cogliati, C., Broggi, C., Carozzi, C., Caldirolo, D., Lombardi, F. and Malliani, A. (1994) Heart period and arterial pressure variabilities in quadriplegic pa- tients. American Journal of Physiology, 266, H1112H1120.

[12]   Koh, J., Brown, T.E., Beightol, L.A., Ha, C.Y. and Eckberg, D.L. (1994) Human autonomic rhythms: Vagal cardiac mechanisms in tetraplegic patients. Journal of Physiology, 471, 483-495.

[13]   Garrido, A., Cruz, de la B., Garrido, M.A., Medina, M. and Naranjo, J. (2009) Variabilidad de la frecuencia cardiaca en un deportista juvenil durante una competición de bádminton de máximo nivel. Revista Andaluza de Medicina del Deporte, 2, 70-74.

[14]   Sarmiento, Y.S., Martín-González, J.M., Rodríguez-Ruiz, D., Quiroga, M.E. and García-Manso, J.M. (2009) Aplicación de la variabilidad de la frecuencia cardiaca en la caracterización de deportistas de élite de lucha canaria con diferente nivel de rendimiento. Revista Andaluza de Medicina del Deporte, 2, 120-125.

[15]   Aubert, A., Seps, B. and Beckers, F. (2003) Heart rate— Variability in athletes. Sports Medicine, 33, 889-919. doi:10.2165/00007256-200333120-00003

[16]   Aubert, A.E., Beckers, F. and Ramaekers, D. (2001) Shortterm heart rate variability in young athletes. Journal of Cardiology, 37, 85-88.

[17]   Pumprla, J., Howorka, K., Groves, D., Chester, M. and Nolan, J. (2002) Functional assessment of heart rate variability: Physiological basis and practical applications. International Journal of Cardiology, 84, 1-14.

[18]   Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology (1996) Heart rate variability: Standards of measurement, physiological interpretation and clinical use. Circulation, 93, 1043-1065. doi:10.1161/01.CIR.93.5.1043

[19]   Woo, M.A., Stevenson, W.G., Moser, D.K., Trelense, R.B. and Harper, R.M. (1992) Patterns of beat-to-beat heart rate variability in advanced heart failure. American Heart Journal, 123, 704-710. doi:10.1016/0002-8703(92)90510-3

[20]   Kleiger, R.E., Miller, J.P., Bigger, J.T. and Moss, A.J. (1987) Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. The American Journal of Cardiology, 59, 256-262. doi:10.1016/0002-9149(87)90795-8

[21]   Kleiger, R.E., Bosner, M.S., Rottman, J.N. and Stein, P.K. (1993) Time-domain measurements of heart rate variability. Journal of Ambulatory Monitoring, 6, 1-18.

[22]   Nolan, J., Batin, P.D., Andrews, R., Lindsay, S.J., Brooksby, P., Mullen, M., Baig, W., Flapan, A.D., Cowley, A., Prescott, R.J., Neilson, J.M. and Fox, K.A. (1998) Prospective study of heart rate variability and mortality in chronic heart failure. Circulation, 98, 1510-1516. doi:10.1161/01.CIR.98.15.1510

[23]   Algra, A., Tijssen, J.G.P., Poelandt, J.R.T.C., Pool, J. and Lubsen, J. (1993) Heart rate variability from 24-hour electrocardiography and the 2-year risk for sudden death.Circulation, 88, 180-185. doi:10.1161/01.CIR.88.1.180

[24]   Gamelin, F.X., Berthoin, S. and Bosquet, L. (2006) Validity of the polar S810i Heart rate monitor to measure R-R intervals at rest. Medicine & Science in Sports & Exercise, 38, 887-893. doi:10.1249/01.mss.0000218135.79476.9c

[25]   Mietus, J.E., Peng, C.K., Henry, I., Goldsmith, R.L. and Goldberger, A.L. (2002) The pNNx-files: Re-examining a widely-used heart rate variability measure. Heart, 88, 378-380. doi:10.1136/heart.88.4.378

[26]   De la Cruz, B. and Naranjo, J. (2010) Use of pNNx statistics in the evaluation of heart rate variability at rest and during exercise. Archivos de Medicina del Deporte, 138, 181-190.

[27]   Kamen, P.W., Krum and H., Tonkin, A.M. (1996) Poincaré plots of heart rate variability allows quantitative display of parasympathetic nervous activity in humans. Clinical Science, 91, 201-208.

[28]   Tulppo, M.P., M?kikallio, T.H., Takala, T.E.S., Sepp?nen, T. and Huikuri, H.V. (1996) Quantitative beat-to-beat analysis of heart rate dynamics during exercise. American Journal of Physiology, 271, H244-H252.

[29]   Toichi, M., Sugiera, T., Murai, T. and Sengoku, A. (1997) A new method of assessing cardiac autonomic function and its comparison with spectral analysis and coefficient of variation of R-R interval. Journal of the Autonomic Nervous System, 62, 79-84. doi:10.1016/S0165-1838(96)00112-9

[30]   Nunan, D., Sandercock, G.R.H. and Brodie, D.A. (2010) A quantitave systematic review of normal values for short-term heart rate variability in healthy adults. Pacing and Clinical Electrophysiology, 33, 1407-1417. doi:10.1111/j.1540-8159.2010.02841.x

[31]   Zulfiqar, U., Jurivich, D.A., Gao, W. and Singer, D.H. (2010) Relation of high heart rate variability to healthy longevity. American Journal of Cardiology, 105, 1181- 1185. doi:10.1016/j.amjcard.2009.12.022

[32]   Kuo, T.B., Lin, T., Yang, C.C., Li, C.L., Chen, C.F. and Chou, P. (1999) Effect of aging on gender differences in neural control of heart rate. American Journal of Physiology: Heart and Circulatory Physiology, 277, H2233- H2239.

[33]   Migliaro, E.R., Contreras, P., Bech, S., Etxagibel, A., Castro, M., Ricca, R. and Vicente, K. (2001) Relative influence of age, resting heart rate and sedentary life style in short-term analysis of heart rate variability. Brazilian Journal of Medical and Biological Research, 34, 493-500. doi:10.1590/S0100-879X2001000400009

[34]   Ribeiro, T.F., Azevedo, G.D., Crescêncio, J.C., Mar?es, V.R.F.S., Papa, V., Catai, A.M., Verzola, R.M.M., Oliveira, L., Silva, de Sá M.F., Gallo, L. and Silva, E. (2001) Heart rate variability under resting conditions in postmenopausal and young women. Brazilian Journal of Medical and Biological Research, 34, 871-877. doi:10.1590/S0100-879X2001000700006

[35]   Soejima, K., Akaishi, M., Oyamada, K., Meguro, T., Mitamura, H. and Ogawa, S. (1999) Influence of age on ambulatory electrocardiogram-derived heart rate variability. Canadian Journal of Cardiology, 15, 181-184.

[36]   Lerma, C., Vallejo, M., Urias, K., Hermosillo, A. and Cárdenas, M. (2006) Diferencias en la modulación autónoma del corazón entre mujeres y hombres. Archivos de cardiología de México, 76, 277-282.

[37]   Berkoff, D.J., Cairns, C.B., Sanchez, L.D. and Moorman, C.T. (2007) Heart rate variability in elite American track- and-field athletes. Journal of Strength & Conditioning Research, 21, 227-231. doi:10.1519/00124278-200702000-00041

[38]   Sandercock, G.R.H., Bromley, P.D. and Brodie, D.A. (2005) Effects of exercise on heart rate variability: Inferences from meta-analysis. Medicine & Science in Sports & Exercise, 37, 433-439. doi:10.1249/01.MSS.0000155388.39002.9D

[39]   Gregoire, J., Tuck, S., Yamamoto, Y. and Hughson, R.L. (1996) Heart rate variability at rest and exercise: Influence of age, gender, and physical training. Canadian Journal of Applied Physiology, 21, 455-470. doi:10.1139/h96-040

[40]   Maciel, B.C., Gallo, L., Marin, N.J., Lima, E.C. and Mar- tins, L.E.B. (2003) Effects of aerobic training on heart rate. Revista Brasileira de Medicina do Esporte, 9, 104-112.

[41]   Goldsmith, R.L., Bloomfield, D.M. and Rosenwinkel, E.T. (2000) Exercise and autonomic function. Coronary Artery Disease, 11,129-135. doi:10.1097/00019501-200003000-00007

[42]   Bigger, J.T., Fleiss, J.L., Steinman, R.C., Rolnitzky, L.M., Kleiger, R.E. and Rottman, J.N. (1992) Frequency domain measures of heart period variability and mortality after myocardial infarction. Circulation, 85,164-171. doi:10.1161/01.CIR.85.1.164

[43]   Hadasa, M., Azume, A., Zen, K., Asada, S., Kawasaki, T., Kamitavi, T., Kawasaki, S., Sugihara, H. and Matsubara, H. (2004) Very low frequency power of heart rate variability is a powerful predictor of clinical prognosis in patients with chronic heart failure. Circulation Journal, 68, 343-347. doi:10.1253/circj.68.343

[44]   Guzzetti, S., Mezzetti, S., Magatelli, R., Porta, A., De Angelis, G., Rovelli, G. and Malliani, A. (2000) Linear and non-linear 24 h heart rate variability in chronic heart failure. Autonomic Neuroscience, 86, 114-119. doi:10.1016/S1566-0702(00)00239-3

[45]   La Rovere, M.T., Pinna, G.D., Maestri, R., Mortara, A., Capomolla, J., Febo, O., Ferrari, R., Franchini, M., Gnemmi, M., Opasich, C., Riccardi, P.G., Traversi, E. and Cobelli, F. (2003) Short-term heart rate variability strongly predicts sudden cardiac death in chronic heart failure patients. Circulation, 107, 565-570. doi:10.1161/01.CIR.0000047275.25795.17

[46]   Perini, R., Fisher, N., Veicsteinas, A. and Pendergast, D.R. (2002) Aerobic training and cardiovascular responses at rest and during exercise in older men and women. Medicine & Science in Sports & Exercise, 34, 700-708. doi:10.1097/00005768-200204000-00022

[47]   Mourot, L., Bouhaddi, M., Perrey, S., Cappelle, S., Henriet, M.T., Wolf, J.P., Rouillon, J.D. and Regnard. J. (2004) Decrease in heart rate variability with overtraining: Assessment by the Poincaré plot analysis. Clinical Physiology and Functional Imaging, 24, 10-18. doi:10.1046/j.1475-0961.2003.00523.x

[48]   Capdevila, L., Rodas, G., Oca?a, M., Parrado, E., Pintanel, M. and Valero, M. (2008) Variabilidad de la frecuencia cardiaca como indicador de salud en el deporte: Validación con un cuestionario de calidad de vida (SF-12).Apunts Medicine, 158, 62-69.

[49]   Kim, G.M. and Woo, J.M. (2011) Determinants for heart rate variability in a normal Korean population. Journal of Korean Medicine Science, 26, 1293-1298. doi:10.3346/jkms.2011.26.10.1293