OJAnes  Vol.2 No.3 , July 2012
Differences of Heart Rate Variability during Sevoflurane Anesthesia in Children by Age
ABSTRACT
Background: The child’s central nervous system develops with aging, and heart rate variability (HRV), which is con-trolled by the brain, differs from that of adults. We investigated changes in HRV during sevoflurane anesthesia in children. Methods: One 138 children aged from 2 - 12 years without major underlying problems were enrolled. During maintenance with 2 - 2.5 vol% sevoflurane anesthesia, electrocardiographic data were obtained and power spectral analysis, approximate entropy (ApEn) or Hurst exponent were analyzed and compared in three groups (age 2 - 5 years, 6 - 9 and 10 - 12 years of age). Results: The RR interval increased with aging, but low-frequency powers did not. High- frequency power was greater in the oldest children (P < 0.05), while ApEn and Hurst exponents were lower (P < 0.05). Conclusion: Change in HRV is one of the characteristics of development in children.

Cite this paper
Y. Park, C. Koo, J. Kim, H. Kim and H. Byon, "Differences of Heart Rate Variability during Sevoflurane Anesthesia in Children by Age," Open Journal of Anesthesiology, Vol. 2 No. 3, 2012, pp. 74-78. doi: 10.4236/ojanes.2012.23018.
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