OJOG  Vol.2 No.2 , June 2012
Atypical presentation and localization of granulosa cell tumor—A case report and review of the literature
Introduction: Extraovarian granulosa cell tumor (GCT) is a very uncommon tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. Case report: We report the case of a 25 year-old woman who was presented at the emergency unit with a severe abdominal pain focused on the left iliac fossa. The patient had delivered normally 2 months before. An ovarian mass of 79 × 67 × 89 mm was shown in vaginal ultrasound as well as at the abdominal scan. Exploratory laparoscopy was performed and a torsion of the fallopian tube and an hemato-salpinges was visualized. Re-vascularisation was not achieved and a left salpingectomy took place. The immuno-histopathology report revealed an extra-ovarian GCT deriving from the fimbriae of the tube. Follow-up surgery was discussed. The case is presented for its rarity.

Cite this paper
Grigoriou Sakkas, E. , Bucella, D. , Roland De Wind, A. , Stanciu, C. and Buxant, F. (2012) Atypical presentation and localization of granulosa cell tumor—A case report and review of the literature. Open Journal of Obstetrics and Gynecology, 2, 161-163. doi: 10.4236/ojog.2012.22031.
[1]   Naniwadekar, M.R. and Patil, N.J. (2010) Extraovarian granulosa cell tumor of mesentery: A case report. Pathology Research Internation, 4, Article ID 292-606.

[2]   Paul, P.C., Chakraborty, J., Chakrabarti, S., et al. (2009) Extraovarian granulosa cell tumor. Indian Journal of Pathology and Microbiology, 52, 231-233. doi:10.4103/0377-4929.48928

[3]   Reddy, D.B., Rao, D.B. and Sarojini, J.S. (1963) Extraovarian granulosa cell tumor. Journal of the Indian Medical Association, 41, 254-257.

[4]   Keitoku, M., Konishi, I., Nanbu, K., et al. (1997) Extraovarian sex cord-stromal tumor: Case report and review of the literature. International Journal of Gynecological Pathology, 16, 180-185. doi:10.1097/00004347-199704000-00017

[5]   Kim, S.H., Park, H.J., Linton, J.A., et al. (2001) Extraovarian granulosa cell tumor. Yonsei Medical Journal, 42, 360-363.

[6]   Robinson, J.B., Im, D.D., Logan, L., et al. (1999) Extraovarian granulosa cell tumor. Gynecologic Oncology, 74, 123-127. doi:10.1006/gyno.1999.5375

[7]   Vanderstichele, S., Elhage, A., Verbert-Scherrer, A., et al. (1996) Granulosa cell tumors: A case located in the broad ligament of the uterus with normal ovaries. Journal de Gynécologie, Obstétrique et Biologie de la Reproduction, 25, 47-52.

[8]   Sakai, Y. (2007) Granulosa cell tumor arising in the wall of mullerian cyst of the broad ligament: Report of a case and immunohistochemical study. Archives of Gynecology and Obstetrics, 275, 145-148. doi:10.1007/s00404-006-0185-4

[9]   Orselli, R.C. and Bassler, T.J. (1973) Theca granulose cell tumor arising in adrenal. Cancer, 31, 474-477. doi:10.1002/1097-0142(197302)31:2<474::AID-CNCR2820310227>3.0.CO;2-R

[10]   Vihko, K.K., Blauer, M., Puistola, U., et al. (2003) Activin B in patients with granulosa cell tumours: Serum levels in comparison to inhibin. Acta Obstetricia et Gynecologica Scandinavica, 82, 570-574. doi:10.1034/j.1600-0412.2003.00146.x