OJPM  Vol.2 No.2 , May 2012
The effect of zinc supplementation on diarrheal diseases in children in the Niger Delta Sub-Region of Nigeria
ABSTRACT
This study evaluated the trend of diarrheal diseases managed with zinc supplementation by comparing it with diarrheal diseases managed without zinc supplementation at the University of Port Harcourt Teaching hospital (UPTH), Nigeria. The study was a descriptive retrospective study done at the Diarrhea Training Unit (DTU) of UPTH to determine the effect of zinc supplementation in the management of diarrhea in children under 5 years. Out of the 134 case records studied, of children aged 0 to 59 months who presented with diarrhea at the DTU, 57 children did not receive zinc supplementation between October and December, 2007 and 77 children received zinc supplementation between October and December 2009. The results showed that (74) 96.1% of patients who received zinc supplementation, and (48) 84.2% of those who did not, had no repeat diarrheal episodes when seen at the follow up clinic. On the other hand, 1.3% of those who received zinc supplementation and 1.8% of those who did not, had increased episodes of diarrhea when seen at the follow up clinic. Of those who received, and those who did not receive zinc supplementation, 2.6% and 14% respectively, had reduced episodes of diarrhea. These findings clearly demonstrate the effectiveness of zinc supplementation in halting the course of diarrheal diseases in children aged 0 to 59 months. We therefore advocate for the use of zinc supplementation in the management of diarrhea in Nigeria

Cite this paper
Asuquo, E. , Georgewill, U. , Nta, I. , Enyidah, N. , Umofia, E. and Deekae, S. (2012) The effect of zinc supplementation on diarrheal diseases in children in the Niger Delta Sub-Region of Nigeria. Open Journal of Preventive Medicine, 2, 137-140. doi: 10.4236/ojpm.2012.22020.
References
[1]   Khan, P.A. (2008) Infectious diseases. Basis of pediatrics. 7th Edition, Zahid Bashir Printers, Lahore, 201-282.

[2]   Bhutta, Z.A., Black, R.E., Brown, K.H., Gardner, M.J., Gore, S., Hidayat, A., Khatun, F., Martorell, R., Ninh, N.X., Penny, M.E., Rosado, J.L., Roy, S.K., Ruel, M., Sazawal, S. and Shankar A. (1999) Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: Pooled analysis of randomized controlled trials; Zinc Investigators Collaborative Group; Aga Khan University Medical Center, Karachi.

[3]   WHO (1990) World Health Organization Programme for control of diarrheal diseases; a manual for the treatment of diarrhea. WHO, Geneva.

[4]   Bhutta, Z.A., Bird, S.M., Black, R.E., Brown, K.H., Gardner, J.M., Hidayat, A., Khatun, F., Martorell, R., Ninh, N.X., Penny, M.E., Rosado, J.L., Roy, S.K., Ruel, M., Sazawal, S. and Shankar, A. (2000) Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: Pooled analysis of randomized controlled trials. American Journal of Clinical Nutrition, 72, 1516-1522.

[5]   Fischer Walker, C.L. and Black, R.E. (2007) Micronutrients and diarrheal disease. Clinical Infectious Diseases, 45, S73-S77.

[6]   Foutaine, O. (2001) Effect of zinc supplementation on clinical course of acute diarrhea; report of a meeting, New Delhi. Journal of Health Population and Nutrition, 19, 338-346.

[7]   R. K. Adhikari, N. Bhandari, R. J. Ulvik, K. M?lbak, M. K. Bhan and H. Sommerfelt. (2002) Effectiveness and efficacy of zinc for the treatment of acute diarrhea in young children. Pediatrics, 109, 898-903. doi:10.1542/peds.109.5.898

[8]   Al-Sonboli, N., Gurgel, R., Shenkin, A., Hart, C.A. and Cuevas, L. (2003) Zinc supplementation in Brazilian children with acute diarrhea. Annals of Tropical Paediatrics, 23, 3-8. doi:10.1179/000349803125002797

[9]   Centre for Health and Population Research (2001) Effect of zinc supplementation on clinical course of acute diarrhea. Journal of Health, Population and Nutrition, 19, 338-346.

[10]   World Health Organization/United Nations Children’s Fund (2004) Joint statement: Clinical management of acute diarrhea (who/fch/cah/04.07). United Nation Children Emergency Fund, Geneva and New York.

[11]   National Population Commission (NPC) and ICF Macro. (2008) Nigeria Demographic and Health Survey 2008: Key Findings.

[12]   Zinc Investigators’ Collaborative Group (1999) Prevention of diarrhea and Zinc Investigators’ Collaborative Group, Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: Pooled analysis of randomized controlled trials. Journal of Pediatrics, 135, 689-697. doi:10.1016/S0022-3476(99)70086-7

[13]   Fewtrell, L., et al. (2005) Water, sanitation, and hygiene interventions to reduce diarrhea in less developed countries: A systematic review and meta-analysis. The Lancet Infectious Diseases, 5, 42. doi:10.1016/S1473-3099(04)01253-8

[14]   Al-Sonboli, N., Gurgel, R., Shenkin, A., Hart, C.A. and Cuevas, L.E. (2003) Zinc supplementation in brazilian children with acute diarrhea. Annals of Tropical Paediatrics, 23, 3-8. doi:10.1179/000349803125002797

[15]   Lazzerini, M. and Ronfani, L. (2008) Oral zinc for treating diarrhea in children. Cochrane Database of Systematic Reviews, 3. doi:10.1002/14651858.CD005436.pub2

 
 
Top