JBNB  Vol.3 No.2 , April 2012
Electrochemical Analysis of the Redox State of Silver Contained in Antibacterial Material
ABSTRACT
Introduction of silver into some inorganic material causes the resulting mixture to have antibacterial activity. Here, we investigated the role of silver in the bactericidal activity of silver-loaded zeolite, by measuring the effects of silver-loaded zeolite on Escherichia coli cell viability under conditions in which the oxidation state of the silver was controlled electrochemically. Bactericidal activity was observed when the sweeping voltage between 0 and 0.7 V was applied to the silver electrode. When nitrogen gas bubbling or reactive oxygen scavengers were added to the experimental system, bactericidal activity decreased. These results indicated that the redox cycle, Ag0 <—> Ag+, caused the dissolved oxygen to form reactive oxygen species.

Cite this paper
Y. Inoue and H. Hamashima, "Electrochemical Analysis of the Redox State of Silver Contained in Antibacterial Material," Journal of Biomaterials and Nanobiotechnology, Vol. 3 No. 2, 2012, pp. 136-139. doi: 10.4236/jbnb.2012.32019.
References
[1]   R. M. Slawson, H. Lee and J. T. Trevors, “Bacterial Interactions with Silver,” Biometals, Vol. 3, No. 3-4, 1990, pp. 151-154. doi:10.1007/BF01140573

[2]   J. R. Furr, A. D. Russell, T. D. Turner and A. Andrews, “Antibacterial Activity of Actisorb Plus, Actisorb and Silver Nitrate,” Journal of Hospital Infection, Vol. 27, No. 3, 1994, pp. 201-208. doi:10.1016/0195-6701(94)90128-7

[3]   R. J. C.McLean, A. A. Hussain, P. J. Vincent, D. J. Hughes and T. J. N.Smith, “Antibacterial Activity of Multilayer Silver-Copper Surface Films on Catheter Material,” Canadian Journal of Microbiology, Vol. 39, No. , 1993, pp. 895-899. doi:10.1139/m93-134

[4]   G. L. McHugh, R. C. Moellering, C. C. Hopkins and M. N. Swartz, “Salmonella typhimurium Resistant to Silver Nitrate, Chloramphenicol, and Ampicillin,” Lancet, Vol. 1, No. 7901, 1975, pp. 235-240. doi:10.1016/S0140-6736(75)91138-1

[5]   A. Mandal, V. Meda, W. J. Zhang, K. M. Farhan and A. Gnanamani, “Synthesis, Characterization and Comparison of Antimicrobial Activity of PEG/TritonX-100 Capped Silver Nanoparticles on Collagen Scaffold,” Colloids and Surfaces, B: Biointerface, Vol. 90, 2012, pp. 191-196. doi:10.1016/j.colsurfb.2011.10.021

[6]   A. Banu, V. Rathod and E. Ranganath, “Silver Nanoparticle Production by Rhizopus stolonifer and Its Antibacterial Activity against Extended Spectrum β-Lactamase Producing (ESBL) Strains of Enterobacteriaceae,” Materials Research Bulletin, Vol. 46, No. 9, 2011, pp. 1417-1423. doi:10.1016/j.materresbull.2011.05.008

[7]   I. Yu and B. Kelman, “Health and Environmental Impact of Silver Nanomaterials,” Nanomaterials for the Life Sciences, Vol. 1, 2009, pp. 225-234. doi:10.1002/9783527610419.ntls0128

[8]   Y. Inoue, M. Hoshino, H. Takahashi, T. Noguchi, T. Murata, Y. Kanzaki, H. Hamashima and M. Sasatsu, “Bactericidal Activity of Ag-Zeolite Mediated by Reactive Oxygen Species under Aerated Conditions,” Journal of Inorganic Biochemistry, Vol. 92, No. 1, 2002, pp. 37-42. doi:10.1016/S0162-0134(02)00489-0

[9]   Y. Inoue, M. Kogure, K. Matsumoto, H. Hamashima, M. Tsukada, K. Endo and T. Tanaka, “Light Irradiation Is a Factor in the Bactericidal Activity of Silver-Loaded Zeolite,” Chemical & Pharmaceutical Bulletin, Vol. 56, No. 5, 2008, pp. 692-694. doi:10.1248/cpb.56.692

 
 
Top