OJMP  Vol.1 No.2 , April 2012
Correlates of Age at Initial Diagnosis of Chronic Lymphocytic Leukemia: Exercise, ASA & Emotional Distress
ABSTRACT
Objective: No studies of either the cross-sectional or prospective association of behavioral life characteristics and the onset of Chronic Lymphocytic Leukemia (CLL) exist. Methods: Multiple interview or questionnaire measures of emotional distress and social support, as well as personality characteristics, exercise, sleep quality, aspirin or lipid-lowering medication use, smoking status and history, educational history and farming/pesticide exposure were tested as correlates of age at initial diagnosis of CLL (AAID-CLL) in 183 patients recruited from the electronic records of Henry Ford Hospital or internet support sites. Results: Aspirin use, having always been “Fit” and living alone were positively associated with AAID. Negative associations were observed for farming/pesticide exposure, years of education, being married, self description as a “Lone Wolf” or “Worrier”, taking “nerve” or “sleeping” pills, awakenings per night, Packyears of Smoking and the Interpersonal Sensitivity, Depression, Anxiety, Hostility and Paranoia scales of the Symptom Checklist 90 - Revised, as well as the AIAI (anger), Depression and Anxiety scales of the Spouse/Friend Ketterer Stress Symptom Frequency Checklist. Conclusions: Aspirin use and exercise may exert a modifiable delaying influence in the onset of CLL. Conversely, emotional distress and smoking may hasten its onset. Prospective, and interventional, tests of these findings are needed.

Cite this paper
M. Ketterer, E. Ketterer, B. Barthel, A. Hanbali, P. Kuriakose, Y. Guo and W. Knysz, "Correlates of Age at Initial Diagnosis of Chronic Lymphocytic Leukemia: Exercise, ASA & Emotional Distress," Open Journal of Medical Psychology, Vol. 1 No. 2, 2012, pp. 9-14. doi: 10.4236/ojmp.2012.12002.
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