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 JCDSA  Vol.2 No.1 , March 2012
The Effect of Mesobotox Together with Intense Pulsed Light on Facial Wrinkles and Erythema
Abstract: Facial ageing is a gradual process which could be due to intrinsic and extrinsic causes, it ultimately results in the appearance of gravity-induced tissue ptosis, wrinkles, epidermal and dermal atrophy, dryness, senile lentigo, flushing, telangiectasia, and enlarged pores. Mesobotox treatment is a technique of microinjections of diluted Botulinum toxin type A (BTX) to preserve the facial mobility in order to preserve the natural beauty. BTX treatment enhances the aesthetic improvements attained with IPL. Ten patients of age ranging between 40 - 60 years old ( mean 45±10.3 years) with skin type ranging between (III - V) were treated using BTX and Intense Pulsed Light (IPL) using cutoff filter 550 nm with a fluence of 25 J/cm2 together as a combination therapy. All patients received standard IPL treatment and were assigned to receive eight 0.1 mL intradermal injections of BTX in each cheek (8 U total dose). Vertical lines within the forehead also received five 0.1 mL intradermal injections of BTX. Small wrinkles and fine lines, erythema, apparent pore size, skin texture, and overall appearance were evaluated after one week. A significantly higher proportion of patients showed improvement in small wrinkles and erythema with IPL plus BTX compared with the baseline demonstrated by computerized image analysis. In conclusion, A combined therapy of mesobotx and IPL is an effective and safe treatment for fine wrinkles, telangiectasia, flushing.
Cite this paper: A. Bedewi, "The Effect of Mesobotox Together with Intense Pulsed Light on Facial Wrinkles and Erythema," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 2 No. 1, 2012, pp. 16-19. doi: 10.4236/jcdsa.2012.21005.
References

[1]   L. Baumann, “Cosmetic Dermatology; Principles and Practice,” McGraw-Hill Companies, New York, 2002.

[2]   M. S. Zimbler, J. B. Holds, M. S. Kokoska, et al., “Effect of Botulinum Toxin Pretreatment on Laser Resurfacing Results: A Prospective, Randomized, Blinded Trial,” Archives of Facial Plastic Surgery, Vol. 3, No. 3, 2001, pp. 165-169. doi:10.1001/archfaci.3.3.165

[3]   J. Carruthers and A. Carruthers, “A Prospective, Randomized, Parallel Group Study Analyzing the Effect of BTX-A and Nonanimal Sourced Hyaluronic Acid (NASHA, Restylane) in Combination Compared with NASHA (Restylane) Alone in Severe Glabellar Rhytides with a Hyaluronic Acid Derivative Compared with the Derivative and BTXA,” Dermatologic Surgery, Vol. 29, No. 8, 2003, pp. 802-809. doi:10.1046/j.1524-4725.2003.29212.x

[4]   A. El-Bedewi, “Broad Spectrum Intense Pulsed Light Source (IPL)—A New Therapeutic Modality in the Coming Millennium,” Dermatology, Vol. 7, No. 2, 2000, p. 22.

[5]   A. El-Bedewi, “Hair Removal with Intense Pulsed Light,” Lasers in Medical Science, Vol. 19, No. 1, 2004, pp. 48-51.

[6]   M. P. Goldman, R. A. Weiss and M. A. Weiss, “Intense Pulsed Light as a Nonablative Approach to Photoaging,” Dermatologic Surgery, Vol. 31, Suppl. 3, 2005, pp. 1179- 1187. doi:10.1111/j.1524-4725.2005.31924

[7]   D. J. Goldberg and K. B. Cutler, “Nonablative Treatment of Rhytids with Intense Pulsed Light,” Lasers in Surgery and Medicine, Vol. 26, No. 2, 2000, pp. 196-200. doi:10.1002/(SICI)1096-9101(2000)26:2<196::AID-LSM10>3.0.CO;2-9

[8]   A. El-Bedewi “Intense Pulsed Light in Dermatology,” 4th World Congress of the International Academy of Cosmetic Dermatology 2005 (IVth IACD), Paris, France.

[9]   J. G. Khoury, R. Saluja and M. P. Goldman, “The Effect of Botulinum Toxin Type A on Full-Face Intense Pulsed Light Treatment: A Randomized, Double-Blind, Split- Face Study,” Dermatologic Surgery, Vol. 34, No. 8, 2008, pp. 1062-1069. doi:10.1111/j.1524-4725.2008.34207.x

[10]   T. Proebstle, “Skin Displacement Analysis (SDA): A Tool for the Quantitative Evaluation of Skin Movements Elicited by Underlying Muscles in the Face and Neck Area,” Clinical, Cosmetic and Investigational Dermatology, Vol. 4, 2011, pp. 27-33. doi:10.2147/CCID.S18185

[11]   M. Heckmann, S. Breit, A. Ceballos-Baumann, et al., “Side-Controlled Intradermal Injection of Botulinum Toxin A in Recalcitrant Axillary Hyperhidrosis,” Journal of American Academy Dermatology, Vol. 41, No. 6, 1999, pp. 987-990. doi:10.1016/S0190-9622(99)70258-6

[12]   S. K. Kranendonk, L. K. Ferris and S. Obagi, “Re: Botulinum Toxin for the Treatment of Facial Flushing,” Dermatologic Surgery, Vol. 31, 2005, p. 491.

[13]   J. Carruthers and A. Carruthers, “The Effect of Full-Face Broadband Light Treatments Alone and in Combination with Bilateral Crow’s Feet Botulinum Toxin Type A Chemodenervation,” Dermatologic Surgery, Vol. 30, No. 3, 2004, pp. 355-366. doi:10.1111/j.1524-4725.2004.30101.x

 
 
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